Critical Care Topics

Question 1

What increases CO2 production?

Answer 1

Increased metabolic rate (increased activity, sepsis, thyrotoxicosis). Increase in carbohydrates consumed.

Question 2

Suspect _______ in critical care setting when PaO2 is normal and oxygen saturations are low.

Answer 2

Methemaglobinemia.

Question 3

Treatment for methemaglobinemia

Answer 3

Methylene blue to reduce serum ferric iron

Question 4

Mechanism of fomepizole

Answer 4

Inhibits alcohol dehydrogenase

Question 5

Cyanide poisoning antidote

Answer 5

Sodium nitrite and sodium thiosulfate

Question 6

Pulse pressure variation greater than ___ means the patient may respond to fluids

Answer 6

12

Question 7

For pulse pressure variation to be a valid measure the patient must be on _____ tidal volumes.

Answer 7

High (600-800mls)

Question 8

____ has been shown to be effective at reducing bleeding in non-life threatening hemoptysis.

Answer 8

Inhaled TXA

Question 9

Platelet cutoff for transfusion in hemoptysis

Answer 9

<50K

Question 10

Adding a ____ can be useful in relieving double triggering in ventilated patients

Answer 10

Adding a 1 second inspiratory hold at the beginning of each breath

Question 11

______ is a humanized monoclonal antibody that can be used as a corticosteroid-sparing agent in the long-term management of MG

Answer 11

Ravulizumab