Critical Care Flashcards
Change in Delta Pressure to __ mmHg indicates fasciotomy
Change in Delta Pressure from 40 to 20mmHg indicates fasciotomy
Calculation for Delta Pressure for compartments
DBP - compartment pressure = Delta Pressure
Delta P < 20-30 = fasciotomy
Vasopressors are first line for_____ shock
Vasopressors are first line for NEUROGENIC shock
Septic shock tx (3)
- volume resus
- Antibiotics
- then pressors
Cardiogenic shock tx
ionotropes and chronotropes - main goal is increasing contractility
Manifestations of ACS (Inc Intraabdominal pressure leading to ischemia of bowel) (5)
- Inc Intracranial Pressure (nml 7-15)
- Inc Peak Pressures (up to 40)
- Cardiac failure bc of dec preload and inc after load
- Rena Failure- Inc SVR (>2500 dynes)
- GI ischemia
Why inc hyperpigmentation in Cushings?
In Cushings, Inc ACTH - ACTH similar to MSH - increase in melatonin
Nurtition and Extubation; What Macro to change?
Dec the Colories, esp from carbos
Respiratory Quotient >1.0
Overfeeding
balanced = 0.85
What is the most common adverse effect of vasopressin?
Decreased CO (bc dec HR) -- should be added after max Norepi
Initial treatment for invasive aspergillosis in Neutropenic patient
VORIconazole
C. krusei - Vori
C. glabrata - Micfungin
C. albicans - Fluc
Dopamine effects (Low v Mod v High)
Low Dopamine = Dopa-R to increase mesenteric blood flow
Mod Dopa = Beta adrenergic-R and inc contractility
High Dopa = alpha adrenergic, induce vasoconstriction
Emergent Uremic Coagulopathy Tx
DDAVP temporary before
Dialysis
_____ = MC inheritable coagulopathy; why?
Factor V Leiden - Activated Protein C is unable to inhibit the altered Factor V therefore more thombus is made
AKI and increase in Serum Cr?
Increase in plasma Creatinine by < 50% indicative of AKI
Suspected Treacheoinominate fistula s/p Trach 3 weeks ago, how to dx? (steps after)
Flexible bronch, then digital occlusion and cuff overinflation then to OR
Lab findings associated with DIC?
High fibrin split products
Found down, hypotensive brady and warm. Dx?
Neurogenic shock
What causes right shift of O2 binding curve? (4)
- Increased DPG
- Inc Temp
- Inc PP CO2
- Increased H (acidosis)
As the 02 binding curve, goes RIGHT, Hgb has ____ affinity for O2
Right shift of 02 binding curve, Hgb has LESS affinity for 02 meaning it will readily release 02 to tissues
(*think of lactic acidosis bc hypoperfusison)
On the 02 binding curve, Left shift means Hgb has _____ affinty for 02
Left shift = HIGHER affinity, therefore holds on more
__ and ___ cause a LEFT shift in oxygen binding curve
CO and Meth-Hgb