Creatine Kinase Flashcards
1
Q
MW
A
82,000 D
2
Q
Class of enzyme
A
Transferase
3
Q
Associated with
A
ATP regeneration
Transport system
4
Q
Transfase of phosphate group PO4
A
Kinase
5
Q
Ami
A
Acute myocardial infarction
6
Q
Cns shock
A
Sepsis
7
Q
High concentration in
A
Skeletal muscle
Heart muscle
Brain tissue
8
Q
Sensitive indicator for
A
Ami
Md-duchenne type
9
Q
Also seen in CNS disorder such as
A
Stroke, nerve degeneration, seizures, cns shock
10
Q
2 subunits
A
H and M
11
Q
Isoenzymes
A
Ck bb-brain type
Ck mb- hybrid type
Ck mm- muscle type
12
Q
Fastest iso
A
Ck bb
13
Q
Slowest iso
A
Ck mm
14
Q
Most predominant iso in healthy individuals
A
Ck mm
15
Q
Ck mm found in
A
Striated muscle and normal serum
16
Q
Heart muscle activity mostly
A
80% ck mm
20% ck mb
17
Q
Hypothyroidism
A
Ck mm
18
Q
High conc in brain
A
Ck bb
19
Q
Seen in cns, git, uterus
A
Ck bb
20
Q
Pregnancy
A
Ck bb
21
Q
Ck bb used to detect
A
Cns damage
Childbirth
Tumor
