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CREAMS Flashcards

1
Q

Are semi-solid preparations containing
one or more medicinal agents dissolved or dispersed in either an oil-in-water emulsion or in another type of water-washable base.

A

CREAMS

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2
Q

Patients and physicians prefer _____
to ointments because they are easier
to spread and remove than many
ointments.

A

CREAMS

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3
Q

The so-called_____ are oil-in-water emulsions containing large percentage of water and stearic acid or other oleaginous components.

A

Vanishing Creams

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4
Q

Four (4) main ingredients of cold
cream:

A

WATER
OIL
EMULSIFIER
THICKENING AGENT

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5
Q

• Primary application in topical skin products and in products used on mucous. membranes, such as rectally and vaginally.
 The provision of a barrier to protect the skin
 To aid in the retention of moisture.
 As emollient.
 As vehicle for drug substance such as local anesthetics, anti-inflammatories, hormones, antibiotics, antifungals or counter-irritants.

A

CREAMS

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6
Q

Also known as Jellies

A

GELS

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7
Q

Are semi-solid systems consisting of
dispersions of small or large molecules
in an aqueous liquid vehicle rendered
jelly-like by the addition of a gelling
agents

A

GELS

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8
Q

Are semi-solid that can have properties
ranging from soft and weak to hard and
tough.

A

GELS

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9
Q

Are defined as a substantially
dilute cross-linked system, which
exhibits no flow when in the steady-state.

A

GELS

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10
Q

Has been defined phenomenologically
as a soft, solid or solid-like material
consisting of two or more components,
one of which is a liquid, present in
substantial quantity

A

GEL

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11
Q

are usually formed from a fatty acids in the oil phase hydrolyzed by a base dissolved in the aqueous phase in situ during the preparation of creams.

A

SOAPS

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12
Q

may be formulated from a variety of
oils both mineral and vegetable, and from
fatty alcohols, fatty acids, and fatty esters.

A

CREAMS

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13
Q

GELLING AGENTS:

A

Macromolecules: Carbomer 935

Cellulose derivatives:
Carboxymethylcellulose or
Hydroxypropylmethylcellulose

Natural gums: Tragacanth

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14
Q

Other Agents of Gels:

A

 Drug Substance
 Water
 Co-solvents: Alcohol and/or
propylene glycol
 Antimicrobial preservatives:
Methylparaben, propylparaben, or
Chlorhexidine gluconate
 Stabilizers: Edetate disodium

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15
Q

formed with large organic molecules
may be formed by dispersing the molecule in the continuous phase (by heating starch), by cross-linking the dispersed molecules by changing the pH (as for carbomers), or by reducing the continuous phase (as for jellies formed with sucrose)

A

GELS

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16
Q

 Topically applied onto the skin, eyes,
nasally, vaginally and rectally.

 Administered by the topical
oromucosal routes. Antibiotic-
containing gels can be administered
by teat infusion in veterinary
medicine to treat mastitis.

A

GELS

17
Q

 Should be stored in tight containers
to prevent water loss.
 Avoid freezing.

A

GELS

18
Q

Are semi-solid preparations intended for
application to the skin.

A

PASTE

19
Q

They are generally contain a large
proportion of solid material (such as 25%)
than ointments and therefore are stiffer.

A

PASTE

20
Q

When prepared with an oleaginous base
they are greasy than their counterpart
ointments due to the reduced amount of
the base.

A

PASTE

21
Q

 Are prepared in the same manner as
ointments, by direct mixing or the use of
heat to soften the base prior to
incorporating the solids, which have been
comminuted and sieved

 However, when levigating agent is to be used to render the powdered component smooth, a portion of the base is often used rather than a liquid, which would soften the paste.

A

PASTE

22
Q

Applied on the skin, but not suited for
hairy parts of the body– due to its
stiffness and impenetrability.

A

PASTE

23
Q

is prepared by mixing 25% each of zinc oxide and starch with white petrolatum.

A

ZINC OXIDE PASTE

24
Q

Are solid or semi-solid adhesives masses
spread upon a backing material or paper,
fabric, moleskin or plastic. The adhesive
material used is a rubber base or a
synthetic resin.

A

PLASTER

25
Q

_______ used to be official under
the title Adhesive Plaster, the use of this
material being well known.

A

OFFICAL TAPE

26
Q

 Applied to the skin to provide prolonged contact at the site.
 Medicated plasters provide effects at the site of application. They may be cut to
size to conform to the surface to be covered.
 Unmedicated plasters provide protection or mechanical support at the site of
application.

A

PLASTER

27
Q

use on the toes for the removal of corns with keratolytic action of Salicylic acid (10-
40% concentration)

A

SALICYLIC ACID PLASTER

28
Q

Product of plaster?

A

SALICYLIC ACID PLASTER

29
Q

Are plastic masses containing:
o Gelatin (15%)
o Glycerin (40%)
o Water (35%)
o and an added medicinal substance
(10%) as Zinc Oxide.

A

GLYCEROGELATIN

30
Q

 Softening the gelatin in water for
about 10 minutes.
 Heat on a steam bath until the gelatin
is dissolved.
 Add the medicinal substance mixed
with glycerin.
 Allow the mixture to cool with stirring
until congealed.

A

GLYCEROGELATIN

31
Q

Applied to the skin for longer residence.
They are melted before application,
cooled to slightly above body temperature,and applied to the affected area with a fine brush.

 Following application, the
glycerogelatin hardens, is usually covered with abandage and is allowed to remain in placefor a period of weeks

A

GLUCEROGELATIN

32
Q

Product of glycerogelatin

A

ZINC GELATIN

33
Q

Use in the treatment of varicose
ulcers.

A

ZINC GELATIN

34
Q

Zinc Gelatin is also known as _______ due to its ability to form a
pressure bandage.

A

ZINC GELATIN BOOT

35
Q

Zinc gelatin is used for the treatment of?

A

VARICOSE ULCERS

36
Q

Packaging of Glycerogelatin?

Topical dermatologic products- packaged in either?

A

JARS, TUBES OR SYRINGES

37
Q

Topical dermatologic products -
packaged in either jars, tubes, or
syringes.

Ophthalmic, nasal, vaginal and rectal
solid products - tubes or syringes

A

GLYCEROGELATIN

PDF LEC (3 decks)

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