Cranial skull + sutures Flashcards
What is the ‘Anterior fontanelle’ known as
soft spot
Fontanelles are the membrane covered spots in the …….. where 3 or more ……. converge
calvaria
bones
How many fontanelles are there and what are there names
anterior
posterior
sphenoidal
mastoid
What is craniosynostosis
premature fusion of sutures
Calvarial bone development is synchronised with ……… development
brain
What are the two genes that can cause crouzon syndrome?
FGFR2
FGFR3
What is the gene that can cause apert syndrome?
FGFR2
What is the two genes that can cause Pfeiffer?
FGFR1
FGFR2
What does FGFR2 bead induce …….
twist expression
What type of growth does the face follow and what does the skeleton around the eye, middle and inner ear follow
face - somatic
rest - neural
What are the two types of bone in the head?
endochondral
intramembranous
What cartilage is important for growth of the mandible?
Meckel’s cartilage
What do endochondral bones develop from?
cartilage template
What cells give rise to all skeletal structures of the face
neural crest
What happens to the osteoblasts so the skull can develop?
osteoblasts expand and lay down matrix so bone can expand