Cranial Nerves Flashcards

1
Q

What are the cranial nerves?

A

• CRANIAL NERVES= peripheral nerves that emerge directly from the brain (particularly BRAINSTEM= midbrain, pons, & medulla) except CN I & II which emerge from the cerebrum (forebrain)
o Have somatic motor, somatic sensory, and parasympathetic fibers
o Communicate brain with body, targets in head & neck

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2
Q

What are the differences between cranial nerve & spinal nerve?

A

• Cranial nerves emerge directly from the brain/brainstem
o spinal nerves emerge from the spinal cord
• Cranial nerve targets= in head & neck
o spinal nerve targets= in body & limbs
• Cranial nerves can be purely sensory, purely motor, or a mixture both
o spinal nerves are mixed nerves (sensory + motor)
• Some sensory cranial nerves are special sensory (vision, hearing/balance, smell, taste)
o all spinal sensory nerves are general sensory (pain, touch, temperature, & pressure)
• Some motor cranial nerves are branchial motor (supply skeletal muscles derived from embryonic gill arches)
o all spinal motor nerves are general motor (voluntary/somatic; visceral/autonomic)
• Cranial nerves never contain sympathetic fibers as an integral component of their fiber composition
o Sympathetics will follow CN to their target

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3
Q

What are common to cranial nerve & spinal nerve?

A

• Sensory nerves have their cell bodies outside of CNS
o cranial= sensory ganglion outside of brainstem
o spinal= dorsal root ganglion
• Motor nerves have their cell bodies within the CNS
o cranial= within brainstem (cranial nerve motor nuclei)
o spinal= within spinal cord (ventral horn)

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4
Q

List the name and roman numeral of each cranial nerve. Outline what bony foramen or foramina each cranial nerve travels through along its course from the brainstem to its target/targets

A

• CN I= Olfactory Nerve
o Point of Exit: Cribiform plate of ethmoid bone (congregate as olfactory bulb & travel in olfactory tract)
• CN II= Optic Nerve
o Point of Exit: Optic Canal
• CN III= Oculomotor Nerve:
o Point of Exit: Superior Orbital Fissure
• CN IV= Trochlear Nerve
o Point of Exit: Superior Orbital Fissure
• CN V= Trigeminal Nerve
o Point of Exit:
♣ Opthalmic (V1)= Superior Orbital Fissure
♣ Maxillary (V2)= Foramen Rotundum
♣ Mandibular (V3)= Foramen Ovale
• CN VI= Abducens Nerve
o Point of Exit: Superior Orbital Fissure
• CN VII= Facial Nerve
o Point of Exit: Internal Acoustic Meatus
• CN VIII= Vestibulocochlear Nerve
o Point of Exit: Internal Acoustic Meatus
• CN IX= Glossopharyngeal Nerve
o Point of Exit: Jugular Foramen
• CN X= Vagus Nerve
o Point of Exit: Jugular Foramen
• CN XI= Spinal Accessory Nerve
o Point of Exit: Jugular Foramen
• CN XII= Hypoglossal Nerve
o Point of Exit: Hypoglossal Canal

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5
Q

Which cranial nerves are PURELY SENSORY?

A

• 3 Purely Sensory Nerves:
o Olfactory Nerve (CN I)
o Optic Nerve (CNII)
o Vestibulocochlear Nerve (CN VIII)

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6
Q

Which cranial nerves are PURELY MOTOR?

A
•	5 Purely Motor Nerves:
o	Oculomotor Nerve (CN III) 
o	Trochlear Nerve (CN IV)
o	Abducens Nerve (CN VI)
o	Spinal Accessory Nerve (CN XI) 
o	Hypoglossal Nerve (XII)
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7
Q

Which cranial nerves carry SPECIAL SENSORY component?

A
•	6 Nerves carry Special Sensory Component:
o	Olfactory (CN I) Smell
o	Optic (CN II) Vision
o	Facial (CN VII) Taste (anterior 2/3 of tongue)
o	Vestibulocochlear (CN VIII) Hearing (& balance)
o	Glossopharyngeal (CN IX)  Taste (posterior 1/3 of tongue)
o	Vagus (CN X) Taste (root of tongue; taste buds of epiglottis)
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8
Q

Which cranial nerves carry BRANCHIAL MOTOR component? (aka special visceral efferent)

A
•	5 Nerves carry Branchial Motor Component:
o	Trigeminal (CN V) Muscles of Mastication (1st Pharyngeal Arch)
o	Facial (CN VII) Muscles of Facial Expression (2nd Pharyngeal Arch), large component of facial
o	Glossopharyngeal (CN IX) Stylopharyngeus muscle (3rd Branchial Arch), poor man’s facial nerve
o	Vagus (CN X) Pharyngeal & Laryngeal muscles, one extrinsic tongue muscle (4th Branchial Arch)
o	Accessory (CN XI) Sternocleidomastoid & Trapezius muscles (6th Branchial Arch)
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9
Q

Which cranial nerves carry PARASYMPATHETIC nerve fibers?

A
•	4 Nerves carry Parasympathetic Nerve Fibers:
o	Oculomotor (CN III) corresponding ganglion= Ciliary
o	Facial (CN VII) corresponding ganglion= Pterygopalatine & Submandibular
o	Glossopharyngeal (CN IX) corresponding ganglion= Otic
o	Vagus (CN X) synapses in wall of organs
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10
Q

How do parasympathetic nerves in the head differ from those in the body?

A
  • Parasympathetic nerves in the head reach their ganglia & synapse outside of their target organs whereas parasympathetic nerves synapse intramurally (within the target organ’s wall) in the rest of the body
  • all autonomic ganglia in the head are parasympathetic
  • preganglionic parasympathetic fibers reach their target in the head via branches of CN III, VII, or IX
  • postganglionic parasympathetic fibers reach their end organs by hitch-hiking along branches of CN V
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11
Q

What & where are the sensory ganglia of the cranial nerves equivalent to dorsal root ganglia of the spinal nerve?

A

• Cranial Nerve Sensory Ganglia= equivalent to spinal ganglia; located outside the brainstem
o have a peripheral process that is associated with a receptor & a central process that terminates in a cranial nerve sensory nucleus

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12
Q

What is the brainstem’s equivalent of dorsal, ventral, & lateral horns?

A

• Instead of having dorsal (sensory), ventral (motor), or lateral (autonomic) horns like the spinal cord, the brainstem consists of cranial nerve nuclei which correspond to the different fiber types within each cranial nerve (motor, sensory, & parasympathetic)
o Cranial Nerve Motor Nuclei= origin for somatic motor fibers that innervate skeletal muscles of the neck & face
♣ equivalent to ventral horn of spinal cord
o Cranial Nerve Sensory Nuclei= termination of afferent sensory fibers from central processes of cranial nerve sensory ganglia
♣ equivalent to dorsal horn of spinal cord
o Cranial Nerve Parasympathetic Nuclei= CN II, VII, IX, & X; where preganglionic parasympathetic fibers must synapse in the head
♣ equivalent to lateral horn of spinal cord
♣ COPS ganglia ciliary; otic; pterygopalatin; submandibular)

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13
Q

Describe the 4 cranial parasympathetic ganglia & with what cranial nerve each ganglion is associated?

A

• Ciliary Ganglion corresponding nerve= Oculomotor (CN III)
o located in posterior orbit
o preganglionic fibers run with Oculomotor nerve
o postganglionic fibers run in short ciliary nerves to innervate 2 eye muscles:
♣ Sphincter Pupillae= constricts pupil (Miosis)
♣ Ciliaris= accommodation (when it contracts, releases tension on zonular fibers making the lens more convex to allow for near vision)
• Pterygopalatine & Submandibular Ganglia corresponding nerve= Facial (CN VII)
o Pterygopalatine Ganglion= located in pterygopalatine fossa
♣ receives preganglionic fibers from greater petrosal branch of CN VII/Facial
• axons project to lacrimal glands & nasal mucosa
• also innervates venous plexus of nasal conchae to heat/cool air in nose
o Submandibular Ganglion= situated above deep portion of submandibular glans on the hyoglossus muscle near the posterior border of the mylohyoid muscle
♣ receives preganglionic fibers from chorda tympani & lingual nerve branches/tributaries of CN VII/Facial
♣ sends postganglionic fibers to oral mucosa & submandibular & sublingual salivary glands
• Otic Ganglion corresponding nerve= Glossopharyngeal (CN IX)
o small, oval-shaped, flattened parasympathetic ganglion of a reddish-gray color; immediately below the foramen ovale in the infratemporal fossa
o innervates the parotid gland (largest paired salivary gland)
o preganglionic fibers travel along lesser petrosal nerve
o postganglionic fibers travel along auriculotemporal nerve (CN V3)

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14
Q

What cranial nerve do most cranial preganglionic parasympathetic fibers hitchhike along to reach their targets?

A

PREganglionic PARAsympathetic fibers reach their target ganglia in the head via branches of CN III, VII, or IX

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15
Q

Are the sympathetic nerves in the head preganglionic or postganglionic?

A

ALL SYMPATHETIC NERVES IN THE HEAD ARE POSTGANGLIONIC because they already synapsed at the superior cervical ganglion

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16
Q

What is the superior cervical ganglion? How are postganglionic fibers from this ganglion distributed to the head & neck?

A

• PREganglionic sympathetic fibers ascend in sympathetic chain & terminate in SUPERIOR CERVICAL GANGLION (superior termination of chain) at base of skull adjacent to INTERNAL CAROTID ARTERY as it enters the carotid canal
o originate in upper thoracic levels of IML column (T1-T4)
• POSTganglionic sympathetic fibers from the superior cervical ganglion can reach their target organs by:
o 1) jumping on internal carotid arteryfollow if inferiorly to bifurcation from common carotidthen travel along the external carotid artery & its branches to reach target organ
o 2) follow internal carotid artery into craniumfollow branches of TRIGEMINAL SYSTEM
o 3) travel on their own before joining with other nerves

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17
Q

What is Horner’s Syndrome? How is it characterized clinically?

A

• HORNER’S SYNDROME interruption of cervical sympathetic trunk that manifests as the absence of sympathetically stimulated functions on the ipsilateral (same) side of the head
o Symptoms= constriction of pupils (miosis) from dilator pupillae not working (sympathetic) and sphincter pupillae (parasympathathetic, constriction) being opposed ; drooping of superior eyelid (ptosis) from superior tarsal (sympathetic, tone of eyeline) damage, redness & increased temperature of skin (vasodilation, no sympathetic); absence of sweating (anhydrosis, no sympathetic)

18
Q

Trace the path of CN III parasympathetics from the brainstem to their targets (sphincter pupillae & ciliaris muscles)

A

• PARAsympathetic (GVE) fibers innervate smooth muscular sphincter pupillae & ciliaris
o PREganglionic parasympathetic cell bodies are located in the Edinger Westfall (accessory oculomotor) nucleus
o fibers travel in the INFERIOR DIVISION OF III & synapse on POSTganglionc cell bodies in the CILIARY GANGLION
o POSTganglionic fibers travel directly to the eye via SHORT CILIARY NERVES (branches of CN VI)

19
Q

What function does sphincter pupillae serve? What does ciliary muscle do when it contracts? What is the process of accommodation in the eye?

A

• Sphincter Pupillae constricts the pupil= Miosis
• Ciliary Muscle contraction/relaxation changes the shape of the lens to adjust the focus of their vision= ACCOMMODATION
o when relaxed the lens lies flatFar vision
o when contracted the lens becomes convex Near vision (parasympathetic stimulation)

20
Q

How does an oculomotor nerve lesion present? How will the pupil & upper eyelid appear?

A

• When lesioned, results in dilated pupil, ptosis (droopy upper eyelid), pupil is directed “down & out”
o innervates levator palpebrae superioris (lifts lid); superior rectus (lifts eyeball); inferior rectus (downward motion of eyeball); medial rectus (ADduction of eyeball); inferior oblique (upward motion of eyeball-attaches to back of eyeball)

21
Q

Which cranial nerve exits the DORSAL side of the brainstem?

A

• TROCHLEAR NERVE (CN IV) purely somatic motor nerve supplying superior oblique muscle that arises from the DORSAL aspect of the brainstem (unlike the other CN, which exit the ventral side of the brain)
o enters the orbit via the SUPERIOR ORBITAL FISSURE
o cell bodies originate in trochlear nucleus of the pons

22
Q

How will a patient with a trochlear nerve lesion present clinically?

A

• Trochlear Nerve Lesion= patient is unable to look down when the eye is adducted (isolate the superior oblique by adducting the eye; puts the axis of the eyeball/optic nerve in line with the axis of the superior oblique muscle)

23
Q

How will a patient with an abducens nerve lesion present clinically?

A

• Abducens Nerve (CN VI)= purely somatic motor nerve supplying the lateral rectus muscle
o pass through the cavernous sinus & enter the orbit via the SUPERIOR ORBITAL FISSURE
• Abducens Nerve Lesion patient is unable to ABduct the eye

24
Q

What 2 openings in the skull does CN XI travel through?

A

• SPINAL ACCESSORY NERVE (CN XI)= purely somatic motor nerve supplying trapezius & sternocleidomastoid
o spinal rootlets from the upper 5 segments of spinal cord coalesce & enter the skull through the FORAMEN MAGNUM & then travel along the inner wall to exit the skull via the JUGULAR FORAMEN

25
Q

How would a CN XI nerve lesion present clinically?

A

• Spinal Accessory Nerve Lesion patients experiences shoulder “droop” (& impairment of rotary movements of neck & chin to the opposite side)

26
Q

How would a hypoglossal nerve lesion present clinically?

A

• HYPOGLOSSAL NERVE (CN XII) purely somatic MOTOR to the tongue; innervates all intrinsic & extrinsic musculature EXCEPT palatoglossus
o leaves the cranial cavity through the HYPOGLOSSAL CANAL

27
Q

What is anosmia?

A

• ANOSMIA= loss of sense of smell
o usually occurs with aging
o chief complaint= loss/alteration of taste
o most easily torn in trauma (cribiform plate fracture) & CSF will drip from the nose (CSF rhinorrhea)

28
Q

What nerve carries somatic sensory information from the face?

A
•	TRIGEMINAL NERVE (CN V)= principal sensory nerve of the head & face (+ small motor component)
o	3 Divisions:
♣	1) OPTHALMIC DIVISION (V1)
♣	2) MAXILLARY DIVISION (V2)
♣	3) MANDIBULAR DIVISION (V3)
29
Q

What is the sensory ganglion of CN V?

A

• TRIGEMINGAL GANGLION= cell bodies of sensory fibers located on petrous ridge of temporal bone within middle cranial fossa (OUTSIDE of central nervous system)

30
Q

What are the 3 divisions of CN V? What areas of the face & head do they innervate?

A

• OPTHALMIC DIVISION (V1)= sensory territory above LATERAL CORNERS OF EYES
o passes through superior orbital fissure to enter the orbit
• MAXILLARY DIVISION (V2)= sensory territory between LATERAL CORNERS OF EYES & CORNERS OF MOUTH
o passes through foramen rotundum to enter pterygopalatine fossa; divides into 5 branches
♣ infraorbital nerve
♣ greater & lesser palatine nerves
♣ zygomatic nerves
♣ posterior superior alveolar nerves
♣ nasal branches (superior & middle concha; nasal septum)
• MANDIBULAR DIVISION (V3)= sensory territory associated with MANDIBLE (also contains motor fibers)
o passes through foramen ovale into infratemporal fossa; divides into 5 branches
♣ inferior alveolar nerve
♣ lingual nerve
♣ buccal nerve
♣ auriculotemporal nerve
♣ Motor Nerves muscles of mastication; mylohyoid; anterior belly of digastric; tensor veli palatine; tensor tympani

31
Q

Which divisions of CN V are purely sensory? Which division carries motor fibers?

A
  • Purely Sensory Divisions of CN V= OPTHALMIC & MAXILLARY
  • MANDIBULAR= carries sensory & motor fibers
32
Q

What opening in the skull does each of the 3 divisions of the trigeminal nerve pass through?

A
  • OPTHALMIC (V1) Superior Orbital Fissure
  • MAXILLARY (V2) Foramen Rotundum
  • MANDIBULAR (V3) Foramen Ovale
33
Q

Through what opening does the facial nerve exit the cranial cavity? What other cranial nerve exits the cranial cavity through this opening? Through what opening does the facial nerve exit the base of the skull?

A

• FACIAL NERVE (CN VII)= exits cranial cavity via the INTERNAL ACOUSTIC MEATUS (along with CN VIII/ VESTIBULOCOCHLEAR NERVE)
o after traveling through facial canal, somatic motor & sensory fibers take a sharp turn to exit the base of the skull through the STYLOMASTOID FORAMEN

34
Q

What nerve supplies the face with motor innervation (muscles of facial expression)?

A

• Somatic Motor Fibers of the FACIAL NERVE (CN VII) innervate the muscles of facial expression (stapedius; stylohyoid; posterior belly of digastric muscle)
o originate in the facial motor nucleus

35
Q

What is the sensory ganglion for the facial nerve? Where is this ganglion located in the temporal bone?

A

• All sensory fibers arise from cell bodies in GENICULATE GANGLION
o located in bend of facial canal in the temporal bone posterior to middle ear)
o Somatic Sensory= innervate external ear
o Special Sensory= taste innervation to the anterior 2/3 of tongue

36
Q

What 2 branches of the facial nerve carry PARASYMPATHETIC fibers? Which cranial parasympathetic ganglion does each branch synapse in?

A

• Within the temporal bone, the facial nerve gives of GREATER PETROSAL NERVE & CHORDA TYMPANI
o Greater Petrosal Nerve= PREganglionic PARAsympathetic
♣ synapses in PTERYGOPALATINE GANGLION innervates lacrimal gland; nasal mucosa; palatal mucosa
o Chorda Tympani= PREganglionic PARAsympathetic
♣ synapses in SUBMANDIBULAR GANGLION innervates submandibular & sublingual salivary glands

37
Q

Which cranial nerves carry TASTE sensation?

A
  • FACIAL NERVE (CN VII) taste sensation to anterior 2/3 of tongue
  • GLOSSOPHARYNGEAL NERVE (CN IX) taste sensation to posterior 1/3 of tongue
38
Q

What is the cavernous sinus? What structures pass through it? What nerves travel through the lateral wall of it?

A

• CAVERNOUS SINUS venous plexus of extremely thin-walled veins that extend from superior orbital fissure anteriorly to the apex of the petrous part of temporal bone posteriorly
o receives blood from superior & inferior ophthalmic veins, superficial middle cerebral vein, & sphenoparietal sinus
o located bilaterally on each side of the stella turcica on the body of the sphenoid bone
o Contents= internal carotid artery; carotid plexus of sympathetic nerves; oculomotor nerve (CN III); trochlear nerve (CN IV); ophthalmic (CN V1) & maxillary (CN V2) divisions of trigeminal nerve; abducent nerve (CV VI)
♣ the two branches, opthalmic and maxillary of trigeminal nerve are located externally to the wall of the cavernous sinus, which becomes important in the differential diagnosis of lesions of the cavernous sinus - lesions of these nerves tend to distort the sinus rather than occupy it

39
Q

What innervates the posterior and anterior diagastrics?

A

Anterior diagastric- nerve to mylohyoid of IAN of V3

Posterior- CN VII

40
Q

Innervation of stylo and geniohyoid mm?

A

stylohyoid- CN VII

Geniohyoid- C1 via hypoglossal N (N to thyrohyoid)

41
Q

Name infrahyoid muscles and innervation

A

Omohyoid, sternohyoid, sternothyroid- ansa cervicalis

thyrohyoid- nerve to thyrohyoid (C1 via hypoglossal)