Cranial Nerves 1 - 6 Flashcards
The majority of cranial nerves exit the ____ surface of the brainstem, but there are exceptions. CN I and II project to _____, and CN IV exits the dorsal surface of the ___ ____.
____ exits ventrally but not in the brainstem (it has a spinal origin).
The majority of cranial nerves exit the ventral surface of the brainstem, but there are exceptions. CN I and II project to forebrain, and CN IV exits the dorsal surface of the caudal midbrain.
CN XI exits ventrally but not in the brainstem(it has a spinal origin).
Taste is a part of 3 mixed nerves: ___, ___ and ___ cranial nerves.
Taste is a part of 3 mixed nerves: facial (CN VII), glossopharyngeal (CN IX), and vagus (CN X)
The trigeminal nerve supplies both ___ and ___ innervation to various parts of the head and neck. What are the three V’s?
Two of them, ___ and ___, are purely ___.
The trigeminal nerve supplies both sensory and motor innervation to various parts of the head and neck.
The three V’s are:
V1 - Opthalmic
V2 - Maxillary
V3 - Mandibular
Two of them, opthalmic and maxillary, are purely sensory.
______ division (CN V (V1)), is asensory nerve that passes through the_______ andsupplies the eyeball, conjunctiva, lacrimal gland and sac, nasal mucosa, frontal sinus, external nose, upper eyelid, forehead and scalp.
Opthalmic division (CN V), is asensory nerve that passes through the superior orbital fissure and supplies the eyeball, conjunctiva, lacrimal gland and sac, nasal mucosa, frontal sinus, external nose, upper eyelid, forehead and scalp.
_______ division (CN V (V2) ) is a sensory nerve that passes through the_____ ____. It relays sensory info from the skin of the face over the maxillam including the upper lip, maxillary teeth, nasal mucosa, maxillary sinuses and palate.
Maxillary division (CN V ) is asensory nerve that passes through the foramen rotundum. It relays sensory info from the skin of the face over the maxilla including the upper lip, maxillary teeth, nasal mucosa, maxillary sinuses and palate.
The third division of the trigeminal nerveis both a ___ and ____ nerve. The _______ division (CN V - v3) passes through the ___ ___ and is both a sensory and motor nerve. The motor component supplies the muscles of _____, myohyoid, anterior belly of the digastric, tensor veli palatini and tensor tympani.
Sensation from the skin over the mandible, including the lower lip and side of the head, mandibular teeth, mucosa of the mouth and the anterior two thirds of the tongue is also relayed by CN V .
The third division of the trigeminal nerve is both a motor and sensory nerve. The MANDIBULAR division (CN V ) passes through the FORAMEN OVALE and is both a sensory and motor nerve. The motor component supplies the MUSCLES OF MASTICATION, myohyoid, anterior belly of the digastric, tensor veli palatini and tensor tympani.
Sensation from the skin over the mandible, including the lower lip and side of the head, mandibular teeth, mucosa of themouth and the anterior two thirds of thetongue is also relayed by CN V .
Mandibular nerve mnemonic:
“My Tensors Dig Ants 4 MoM” (Mylohyoid—Tensor Tympani + Tensor Veli Palatini—Digastric(Anterior) – 4 Muscles of Mastication (Temporalis, Masseter, Medial and Lateral Pterygoids)
CN___:
FUNCTION: special sensory (or visceral afferent - smell).
These nerve fibers pass through foramina in the ____ of the ____ bone,pierce the dura and arachnoid of the brain and enter the olfactory bulb. In addition to enabling us to smell, ____ also induces visceral responses via the autonomic nervous system. For example, salivation is initiated in response to the aroma of food.
CN I - Olfactory
FUNCTION: special sensory (or visceralafferent - smell).
The olfactory nerve fibers are collectivelyknown as CN I. The fibers pass through foramina in the CRIBRIFORM PLATE of the ethmoid bone, pierce the dura and arachnoid of the brain and enter the olfactory bulb. In addition to enabling us to smell, CN I also induces visceral responses via the autonomic nervous system. For example, salivation is initiated in response to the aroma of food.
___ innervates 4 or 6 extraocular muscles.
Is this parasympathetic or sympathetic?
FUNCTIONS: innervates 4 of the 6 extraocular muscles.
The oculomotor nerve is the chief motor nerve for the ocular and extraocular muscles. It leaves the cranial cavity and enters the __ __ __.
Within this fissure the nerve divides into the superior and inferior divisions. The inferior division also carries presynaptic autonomic fibers to the __ __. The superior division carries fibers to the __ __ and __ __.
CN III - Oculomotor
This supplies parasympathetic motor neurons to ciliary muscle and sphincter pupillae.
FUNCTIONS: innervates 4 of the 6 extraocular muscles.
The oculomotor nerve is the chief motor nerve for the ocular and extraocular muscles. It leaves the cranial cavity and enters the SUPERIOR ORBITAL FISSURE.
Within this fissure the nerve divides into the superior and inferior divisions. The inferior division also carries presynaptic autonomic fibers to the CILIARY GANGLION. The superior division carries fibers to the levator palpibrae and superior rectus.
____ function is to supply motor innervation to the superior oblique extraocular muscles. This nerve passes through the___ ___ ____, where it supplies the superior oblique muscle of the eye.
Injury to this nerve inhibits the eyeball from turning out and down (inferolaterally). This is seen clinically aa ____ (aka double vision).
This nerve is the only cranial nerve to emerge dorsally from the brainstem.
CN IV’s (trochlear) function is to supply motor innervation to the superior oblique extraocular muscles. This nerve passes through the superior orbital fissure where itsupplies the superior oblique muscle of the eye (Remember, Live Frankly To See Absolutely No Insult).
Injury to this nerve inhibits the eyeballfrom turning out and down (inferolaterally).This is seen clinically as DIPLOPIA (doublevision).
CN IV is the only cranial nerve to emerge dorsally from the brainstem.
____ nerve function is to supply motor innervation to the lateral rectus extraocular muscles. This nerve arises between the ___ and the ___ (___ junction) on the brain and wil ltravel through the __ ___ ___ to innervate the lateral rectus muscle. The action of this muscle is to ___ the eye.
CN VI’s (abducens) function is to supply motor innervation to the lateral rectus extraocular muscles. The abducens nerve arises between the pons and the medulla (PMJ) on the brain, and will travel through the superior orbital fissure to innervate the lateral rectus muscle. The action of this muscle is to ABDUCT the eye.
In this picture, the bad eye is the RIGHT eye. She cannot ABDUCT her right eye.
___ nerve:
General sensory function: __ and __ divisions
General motor function: ___ divison.
Also, it acts like a trail finder for all parasympathetic pathways
CNV nerve:
General sensory function: V1 (opthalmic) and V2 (Maxillary) divisions
General motor function: V2 (Mandibular) divison.
Also, it acts like a trail finder for all parasympathetic pathways
The oculomotor nucleus originates at the level of the __ __ in the __-__. The muscles it controls are the striated muscle in the levator palpebrae superioris and all extraocular muscles except for the superior oblique muscle and the lateral rectus muscle.
The Edinger-Westphal nucleus supplies ____ fibers to the eye via the ___ ganglion, and thus controls the sphincter pupillae muscle (affecting pupil constriction) and the ciliary muscle (affecting accommodation).
The oculomotor nerve nucleus originates at the level of the superior colliculus in the mid brain. The muscles it controls are the striated muscle in levator palpebrae superioris and all extraocular muscles except for the superior oblique muscle and the lateral rectus muscle.
The Edinger-Westphal nucleus supplies PS fibers to the eye via the ciliary ganglion, and thus controls the sphincter pupillae muscle (affecting pupil constriction) and the ciliary muscle (affecting accommodation).
The olfactory nerve enter the skull through the ___ ___ of the ___ bone to synapse in the Olfactory Bulb.
These olfactory nerves enter the skull through the Cribriform Plate of the Ethmoid Bone to synapse in the Olfactory Bulb.
The ___ ____ is formed by neural processes of neuroepithelia on upper lateral and septal wall of the nasal cavity
Neural processes traverse perforations of the cribriform plate of ethmoid bone and synapse in olfactory bulb.
Third order connections of olfactory bulb form olfactory tract that ends in the orbital frontal cortex and temporal lobe cortex
The olfactory nerve is formed by neural processes of neuroepithelia on upper lateral and septal wall of the nasal cavity
Neural processes traverse perforations of the cribriform plate of the ethmoid bone and synapse in olfactory bulb.
Third order connections of olfactory bulb form olfactory tract ends in the orbital frontal cortex and temporal lobe cortex
Sympathetics come in and will go to the eyelid itself because there is a region on the eyelid that has smooth muscles (tarsal muscles). These muscles are not associated with the levator palpebrae superiororis muscle (which are innervated by which cranial nerve?)
The tarsal muscle is separately innervated by _____ fibers that originate in the ___ ___ cord.
The levator palpebrae superioris muscle elevates and retracts the upper eyelid.
Since smooth muscles located in the eyelid are innervated by sympathetics, how does this relate to Horner’s syndrome?
Sympathetics come in and will go to the eyelid itself because there is a region on the eyelid that has smooth muscles (tarsal muscles). These muscles are not associated with the levator palpebrae superiororis muscle, which are innervated by CN III.
Smooth muscle that is located in the eyelid is innervated by sympathetics.How does this relate to Horner’s syndrome?
Horner’s syndrome is a combination of symptoms that arises when a group of nerves known as the sympathetic trunk is damaged.
The most common clinical signs of Horner’s Syndrome are: Drooping of the eyelid on the affected side (ptosis) The pupil of the affected eye will be constricted (miosis), or smaller than usual. The affected eye often appears sunken (enophthalmos)
1) ___ nucleus of V (a relay for pain and temperature is analogous to the anterolateral pathway for the body)
2) ___ nucleus – (a relay for fine touch is analogous to the dorsal column medial lemniscus pathway for the body)
3) ____ nucleus of V – (a unique nucleus specialized for proprioception of chewing, eye and tongue muscles, this is the ONLY case where sensory neurons are found in the CNS and not in a peripheral ganglion).
1) Spinal nucleus of V (a relay for pain and temperature is analogous to the anterolateral pathway for the body)
2) Principle nucleus – (a relay for fine touch is analogous to the dorsal column medial lemniscus pathway for the body)
3) Mesencephalic nucleus of V – (a unique nucleus specialized for proprioception of chewing, eye and tongue muscles, this is the ONLY case where sensory neurons are found in the CNS and not in a peripheral ganglion).
The first cranial nerve provides the ultimate form of neural _____ – neuron replacement. Most neurons cannot be replaced. The nasal mucosa is a hostile environment. The olfactory epithelium (like all epithelia) has the property of replacement so that when the epithelium is damaged (by chemical or physical trauma) it can be regenerated or replaced. Neurons in the olfactory epithelium are always being replaced by ___ ___.
The first cranial nerve provides the ultimate form of neural plasticity – neuron replacement. Most neurons cannot be replaced. The nasal mucosa is a hostile environment. The olfactory epithelium (like all epithelia) has the property of replacement so that when the epithelium is damaged (by chemical or physical trauma) it can be regenerated or replaced. Neurons in the olfactory epithelium are always being replaced by stem cells.
The olfactory epithelium is specialized with chemoreceptive neurons that have axons that travel through the cribriform plate of the ethmoid bone to the olfactory bulb. Loss of olfaction the sense of smell is called ____.
Note the olfactory epithelium is specialized with chemoreceptive neurons that have axons that travel through the cribriform plate of the ethmoid bone to the olfactory bulb. Loss of olfaction the sense of smell is anosmia
The lens projects an image that is both ____ and ___ ___ on the retina. The temporal retina sees the _____ visual field and the nasal retina sees the _____ visual field. The upper retina the lower visual field and the lower retina the upper visual field.
The lens projects an image that is both reversed and upside down on the retina. The temporal retina sees the nasal visual field and the nasal retina sees the temporal visual field. The upper retina the lower visual field and the lower retina the upper visual field.
The projection of axons from the ganglion cells in the ____ retina crosses at the ___ ___, close to the ___ gland.
In contrast, the projection of the axons on the ____ retina (receiving light from the ____ fields) remains ipsilateral and does not cross at the optic chiasm.
This means information from the ____ visual fields (____ visual fields) must cross in front of the pituitary gland at the optic chiasm while the sensory information from the more ____ or in the ____ visual fields does not cross at the chiasm.
This is important in cases of pituitary tumors where crossing fibers can be more selectively effected by tumor growth.Note the pathway of nasal (crossed) and temporal axons (uncrossed) at the chiasm. The right visual field (from both eyes) projects to the left thalamus and this information is then relayed to the left visual cortex.
The projection of axons from the ganglion cells in the nasal retina crosses at the optic chiasm close to the pituitary gland.
In contrast, the projection of the axons on the temporal retina (receiving light from the nasal fields) remains ipsilateral and does not cross at the optic chiasm.
This means information from the temporal visual fields (lateral visual fields) must cross in front of the pituitary gland at the optic chiasm while the sensory information from the more nasal or in the medial visual fields does not cross at the chiasm.
This is important in cases of pituitary tumors where crossing fibers can be more selectively effected by tumor growth.Note the pathway of nasal (crossed) and temporal axons (uncrossed) at the chiasm. The right visual field (from both eyes) projects to the left thalamus and this information is then relayed to the left visual cortex.
The right visual field (from both eyes) projects to the ____ thalamus and this information is then relayed to the ___ visual cortex.
The right visual field (from both eyes) projects to the left thalamus and this information is then relayed to the left visual cortex.
The bitemporal (in the temporal visual field of both eyes) hemi-anopia (half of the visual field is blind) is due to the fact that fibers from the nasal retina see the temporal visual field in each eye and these fibers must cross at the optic chiasm. The fibers from the temporal retina see the nasal visual field in each eye and these fibers do/do not cross at the chiasm so they will be more likely spared with a pituitary tumor.
The bitemporal (in the temporal visual field of both eyes) hemianopia (half of the visual field is blind) is due to the fact that fibers from the nasal retina see the temporal visual field in each eye and these fibers must cross at the optic chiasm. The fibers from the temporal retina see the nasal visual field in each eye and these fibers do not cross at the chiasm so they will be more likely spared with a pituitary tumor.
CN III: oculomotor nerve innervates AR and the __ __ ___(which opens the eyelid). Is this parasympathetic or sympathetic innervation?
What is oculomotor palsy? The eye is parked __ and ___ with a ____ (dilated) pupil.
How does this happen?
CN III: oculomotor nerve innervates AR and the levator palpebrae superioris (opens eyelid). This is parasympathetic innervation. Sympathetic innervation supplies the tarsal muscles.
Oculomotor palsy: eye is parked down and out with a mydriatic (dilated) pupil
CN III palsy causes ptosis (droopy eyelid), because the levator palpebrae muscle is no longer innervated. The eye is out because CN IV (LR6) is still pulling it out. It will be down because CN IV (SO) is yanking the back of the eye causing the eye to go down.
Lateral gaze palsy is from a defectve __ nerve.
Abducens nerve (CN VI).
SO4LR6AR3
The position of the motor neurons in the nuclei for cranial nerves III and IV are in the midbrain and the motoneurons for cranial nerve VI are in the lower pons.
The nucleus for cn III is under the superior colliculusThe nucleus for cn IV is under the inferior colliculusThe nucleus for CN VI is in the ___ ____ near the ____.III and IV arise from the _____.VI from the ___ ___ ___.The SO (superior oblique) is innervated by ____The LR (lateral rectus) is innervated by CN ___AR (all the rest of the extraocular muscles) are innervated by ____Note that III and VI exit the brain in the midline above (III) and below (VI) the pons while ____ is the only cranial nerve to exit on the dorsal surface. All three nerves enter the orbit through
Note the position of the motor neurons in the nuclei for cranial nerves III and IV are in the midbrain and the motoneurons for cranial nerve VI are in the lower ponsThe nucleus for cn III is under the superior colliculusThe nucleus for cn IV is under the inferior colliculusThe nucleus for cn VI is in the caudal pons near the pontine medullary border.III and IV arise from the midbrainVI from the pontine medullary borderThe SO (superior oblique) is innervated by CN IVThe LR (lateral rectus) is innervated by CN VIAR (all the rest of the extraocular muscles) are innervated by CN IIINote that III and VI exit the brain in the midline above and below the pons while IV is the only cranial nerve to exit on the dorsal surface. All three nerves enter the orbit through