CPT QUIZ Flashcards
What is the drug class of Ramipril?
ACEi
What is the mechanism of action of Clopidogrel?
ADP receptor (P2Y12) antagonist
Aside from asking a patient, how else could you find out their medication history?
- prescriptions
-GP/hospital letters
-dosette box
-medical records
Give some drugs which cause hyperkalaemia…
ACEi (indirect via aldosterone, reduced expression eNac and downstream K+ excretion)
ARB
Spironolactone (potassium sparing diuretic)
heparin
what is the drug class of Doxazosin?
alpha 1 blocker
give an example of an aminoglycoside…
gentamicin
what is a side effect associated with bendroflumethiazide?
hypokalaemia
which antibiotic is used for tonsillitis treatment?
Penicillin V (phenoxymethylpenicillin)
what is the usual dosage of paracetamol? up to what dose?
500mg to 1g QDS, up to a maximum of 4g/24hr
what is the first-line management of C difficile gastroenteritis?
vancomycin (oral) — haemodynamically stable patients
Metronidazole (IV) In addition —- haemodynamically unstable patients
give an example of a LMWH
dalteparin, enoxaparin, tinzaparin
which class of antibiotic can cause Achilles tendon rupture?
quinolones (ciprofloxacin)
Must give safety netting advice when prescribing, if patient begins to feel pain over the insertion of the Achilles tendon they should stop the antibiotic and seek medical attention.
Can methotrexate be taken in pregnancy?
no- teratogenic
Due to MoA being folate antagonist- interferes with development of the neural tube.
give signs of dehydration on physical examination?
reduced skin turgor, dry mucous membranes, sunken eyes
what is the drug class of chlorphenamine?
antihistamine— H2 receptor antagonist
in CURB65 what does each element stand for? and what is the specific parameter?
C- confusion- new onset
Urea- >7 mmol/L
Respiratory rate- >30 breaths per minute
Blood pressure- <90 systolic, <60 diastolic
Age over 65
what is the drug class of amitriptyline?
tricyclic antidepressant
which enzyme is it important to measure before starting azathioprine?
TPMT (thiopurine S-methyltransferase)
what is a side effect of gentamicin?
nephrotoxic/ototoxic
Due to favouring the OAT1 receptor which is favourably expressed at these sites.
how do you treat an opioid overdose? what is the mechanism of action?
naloxone
competitive opioid receptor antagonist
which drug do patients often buy over the counter when they get diarrhoea on holiday? Mechanism of action?
loperamide
Binds to opioid receptors causes decreased gut motility— constipation