CPR Module (SGU) - Anatomy of the Urinary System 1 Flashcards
Which embryological rudiments develop into the urinary system?
intermediate mesoderm and urogenital sinus
Where can you find the intermediate mesoderm?
Between paraxial and lateral mesoderm
What is the urogenital sinus part of?
cloaca
What are the two parts of the urogenital ridge? What arises from each of these components?
1) nephrogenic cord which gives rise to urinary system
2) gonadal ridge which gives rise to genital system
What are the three sequential components of the embryological kidney?
1) Pronephros
2) Mesonephros
3) Metanephros
Which primitive kidney will form the permanent kidney?
Metanephros
When does the pronephros form? When does it regress? Where is it located?
1) fourth week
2) regresses by end of fourth week
3) cervical region
When does the mesonephros form? When does it regress mostly? Where is it located?
1) end of week 4
2) end of second month
3) caudal to the regressing pronephros to the cloaca
In the male embryo, some parts of the mesonephros persist, what are they?
some tubules and mesonephros duct will form ductus deferens, duct of epididymis and efferent ductules
What do the excretory tubules of the mesonephros form?
Primitive Bowman’s capsules and renal tubules
Where do the mesonephric tubules appear and what do they connect with?
appear laterally, grow into an S shaped loop and meet with tufts of primitive glomeruli
When does the metanephros appear?
5th week
What structure do the excretory ducts of the metanephros come from?
metanephric mesoderm
The ureteric bud is an outgrowth from what? What is it initially close to?
mesonephric duct, close to the cloaca
The bud is “capped” by tissue which it eventually penetrates, what is this cap?
metanephric blastema
The ureteric bud forms what structures?
Primitive renal pelvis and major calyces
The renal tubules are formed from what structure and through which process?
formed from clusters of mesenchymal cells from the metanephric blastema. induced by collecting tubules
What causes a lobulated kidney? When is it not pathological?
1) failure of the growth of connective tissue, vascularity, and nephron growth
2) kidney is normally lobulated in fetus
What forms the excretory part of the nephron? What forms the conducting part of the nephron?
1) excretory –> mesenchyme of the metanephric blastema
2) conducting –> ureteric bud
How do glomeruli form?
Through invaginations of the metanephric tubules
Where are the kidneys initially located? Which direction does the hilum face initially?
1) in the pelvis
2) ventrally