CPG basic info

Question 1

Levels of evidence- I

Answer 1

High quality diagnostic studies, prospective studies, RCT, systematic reviews

Question 2

Levels of evidence- II

Answer 2

Lesser quality of #1- There is weaker diagnostic criteria, reference standards, no blinding, < 80% f/p, improper randomization

Question 3

Levels of evidence- III

Answer 3

Case control studies/ retrospective studies

Question 4

Levels of evidence- IV

Answer 4

Case series

Question 5

Levels of evidence- V

Answer 5

Expert Opinion

Question 6

Strength of Evidence- A

Answer 6

Strong evidence- must/ should use- Includes level I study at least, sometimes level II

Question 7

Strength of Evidence- B

Answer 7

Moderate Evidence- should use- single high quality control trial or level II study

Question 8

Strength of Evidence- C

Answer 8

Weak Evidence- Single study or level III or IV

Question 9

Strength of Evidence- D

Answer 9

Conflicting Evidence- High quality study disagrees

Question 10

Strength of Evidence- E

Answer 10

Theoretical/ Foundational Evidence- may use- suspected based on cadavers, models/ principles, basic science/ bench research

Question 11

Strength of Evidence- F

Answer 11

Expert Opinion- may use- Best practice based on clinical experience