Cours Médecine Interne Ac Flashcards

1
Q

Lupus aigue Ac ?

A

Anti ADN natif

Anti Sm

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2
Q

Lupus subaigu Lésions ? Ac ?

A
Lésions anneau 
Anti SSA (septum interventriculaire très riche chez le fœtus -> BAV)
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3
Q

Quels diagnostics devant MAT ?

A

Héparine ?
HELLP ? grossesse
SHU
PTT (créât ne monte pas autant) (ADAM TS13 -> Ac anti ADAM TS13)

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4
Q

Livedo grosse maille tronc

Vs livedo petite maille des membres

A

Livedo petite maille des membres non pathologique le plus souvent chez la jeune fille maigre
Livedo grosse maille tronc toujours pathologique

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5
Q

Sclérodermie cutanée limitée ac ?

A

Remarque ancien CREST ??

Ac anti centromère

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6
Q

Dans quelles pathologie voit on des mégacapillaires ?

A

Sclérodermie

Dermatomyosite

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7
Q

Les ac de la crise rénale ?

A

Anti RNA pol 3

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8
Q

Méthode de mesure des ac anti DNA natif ?

A
  • IF indirecte = crilithiliae Luciliae (parasite ??) semi quantitatif
  • Radioactivité = Farr (sédimente puis mesure radioactivité)
  • immunoenzymatique = ELISA
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9
Q

Particularité des ac anti ENA ?

A

Ac anti antigène soluble : ribosomes …

Anti Sm et anti Ro/SSA Anti La/SSB

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10
Q

Quels pathologies auto immune consomment le complément ?

A

Lupus et cryoglobulinémie type II

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11
Q

Auto ac associés aux myosites (DE chevauchement = non spécifique)

A

Anti RNP
Anti PM Scl
Anti Ku
Anti SSA

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12
Q

La PR est une forme a mi chemin entre connectivite et vascularite ?

A

Vrai :
PR connectivite
PR vascularite (plus rare ++)

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13
Q

Atteinte commune des vascularite ?

A

Petits vaisseaux = POUMON ET REIN

Nerf et peau également

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14
Q

Classification des cryoglobulinémie

A

Type 1: IgG monoclonale
Type 2 : IgM mono (active le complément ++ -> hypocomplémentémie ) + IgG polyclonale
Type 3 : IgG polyclonale + IgM polyclonale

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