Cough and Cold Flashcards

1
Q

What is the first symptom of a cold?

A

Sore throat

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2
Q

On day 2 or 3 of the cold what symptom(s) usually begin?

A

NASAL (post-nasal drainage, nasal obstruction, mildly-moderate tender sinuses)
Clear, thin +/- watery nasal secretions

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3
Q

On days 4-5 of the cold, what symptom(s) usually begins?

A

COUGH

nasal secretions may become thicker and change to yellow or green

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4
Q

On days 7-14 of the cold what usually happens?

A

Resolution of symptoms

Rhinorrhea returns to celar, thin +/- watery nasal secretions

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5
Q

If you have a dry cough with flu like symptoms you may have __________ & _________ in your body.

A

ACHES and PAINS

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6
Q

If you have a cough +/- mucus with nasal congestion, and rhinitis, you may also have ______________ in your throat.

A

pharyngitis

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7
Q

If you have a chesty cough with clear/pale yellow/reen mucus you may also have ________ & __________ in your sinuses and __________in your chest.

A

rhinorrhea & congestion

congestion

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8
Q
Which of the following can be classified as "fever, rhinitis, pharyngitis, "barking" cough, stridor, and dyspnea?"
A. Allergic Rhinitis
B. Asthma
C. Bacterial throat infection
D. Colds
E. Croup
A

E. Croup

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9
Q
Which of the following can be classified as "watery eyes, itchy nose, eyes or throat, sneezing, nasal congestion, watery rhinorrhea, & red, irritated eyes?"
A. Allergic Rhinitis
B. Asthma
C. Bacterial throat infection
D. Colds
E. Croup
A

A. Allergic Rhinitis

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10
Q
Which of the following can be classified as "sore throat (mild-moderate), nasal congestion, rhinorrhea, sneezing, low-grade fever, chills. HA, malaise and cough?"
A. Allergic Rhinitis
B. Asthma
C. Bacterial throat infection
D. Colds
E. Croup
A

D. Colds

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11
Q
Which of the following can be classified as a "sore throat (mod-sever), fever, exudate, and tender anterior cervical adenopathy?"
A. Allergic Rhinitis
B. Asthma
C. Bacterial throat infection
D. Colds
E. Croup
A

C. Bacterial throat infection

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12
Q
Which of the following can be classified as a "ugh, dyspnea and wheezing?"
A. Allergic Rhinitis
B. Asthma
C. Bacterial throat infection
D. Colds
E. Croup
A

B. Asthma

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13
Q
Which of the following can be classified as "chest tightness, wheezing, dyspnea, productive cough, changes in sputum color, persistent fever?"
A. Influenza
B. Otis Media
C. Pneumonia or bronchitis
D. Sinusitis
A

C. Pneumonia or bronchitis

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14
Q
Which of the following can be classified as "myalgia, arthralgia, nonproductive cough, and moderate-severe fever?"
A. Influenza
B. Otis Media
C. Pneumonia or bronchitis
D. Sinusitis
A

A. Influenza

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15
Q
Which of the following can be classified as "tenderness over the sinuses, facial pain aggravated by Valsalva's maneuver or postural changes, fever > 101.5˚ F, tooth pain, halitosis, URT symptoms for > 7 days"
A. Influenza
B. Otis Media
C. Pneumonia or bronchitis
D. Sinusitis
A

D. Sinusitis

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16
Q
Which of the following can be classified as "ear popping, ear fullness, otalgia, otorhea, hearing loss, dizziness?"
A. Influenza
B. Otis Media
C. Pneumonia or bronchitis
D. Sinusitis
A

B. Otis Media

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17
Q

What are some exclusions for self-care for treating a cold?

A
  1. Fever > 101.5˚ F (38.6˚ C)
  2. Chest pain
  3. SOB
  4. worsening of symptoms or development of additional symptoms during self-treatment
  5. Concurrent underlying chronic cardiopulmonary disease (asthma, COPD, CHF)
  6. AIDS or chronic immunosuppressant therapy
  7. Frail patients of advanced age
  8. Infants < 9 months
  9. Hypersensitivity to recommended OTC meds
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18
Q

How should you treat congestion or rhinorrhea?

A

topical saline or decongestant

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19
Q

how should you treat aches and pains?

A

systemic analgesics

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20
Q

How should you treat fever?

A

systemic antipyretics

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21
Q

How should you treat pharyngitis?

A

topical saline or local anesthetic

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22
Q

What if the patient also has additional sleeplessness?

A

change to topical decongestant & 1st gen AH or alcohol containing products

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23
Q

How soon should you reevaluate a patient who has been self-treated for a cold?

A

7-14 days

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24
Q

What are some non pharmacological therapies (LM) for a cold?

A
rest
fluids (tea with lemon and honey + eight 8 oz glasses of water per day) 
Food (chicken soup and hot broths)
raise the head of the bed for infants
increase humidifications
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25
Q

Why is it good to increase humidification when treating a cold?

A

soothes the irritated airways

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26
Q

What are some ways to increase humidification?

A

steamy showers
humidifiers (cool mist!)
vaporizers (warm mist, can add essential oil inhalants)

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27
Q

What are some non-medicated products (NPT) that can help relieve some cold symptoms?

A

topical saline
essential oils
medical supplies

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28
Q

Saline irrigation such as a net-pot can be __________ to help sooth nasal passages

A

warmed

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29
Q

saline nasal _______ are preferred for toddlers

A

drops

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30
Q

Saline gargles help with sore throats and need _______ salt to 8 oz of warm water

A

1 tsp

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31
Q

What type of topical saline can increase risk of sinus infections, probably by impairing the nasal mucosa? How can you decrease this risk?

A

Neti-pots (saline irrigation)

ONLY use 1-2 times day
*Make sure to only use distilled, sterile, filtered or boiled water. Do NOT use tap water! (only wash in sterile water as well)

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32
Q

How to use nasal products?

A
  1. clear nasal passages (blow nose)
  2. aim away from the septum
  3. sniff deeply
  4. wait to blow nose for a few min
  5. wipe tip of device after use
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33
Q

Drops are better than nasal sprays in children between ___ and ___ years old.

A

2-6

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34
Q

What is the right head position when using a nasal spray?

A

keep head upright

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35
Q

What is the right head position when using a nasal pump spray?

A

tilt head forward

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36
Q

What is the right head position when using a nasal inhaler?

A

keep head upright (warm inhaler first, discard after 2-3 months)

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37
Q

What is the right head position when using a nasal drops?

A

told head from side to side and lay on bed. stay on bed for a few minutes
No need to sniff

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38
Q

What are 5 types of essential oils that may help relieve cough and congestion?

A
  1. Camphor
  2. Menthol
  3. Pepperment
  4. Lavender
  5. Eucalyptus
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39
Q

Olbas inhalers can be used in ages ≥ ____ years.

A

2

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40
Q

Triaminic Flowing Vapors are appropriate for children ≥ __________

A

3 months

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41
Q

Theraflu Vapor patch can be used in ages ≥ ____ years

A

2

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42
Q

Little Remedies is appropriate for children ≥ __________

A

3 months (apply to neck and chest up to TID)

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43
Q

True or false. Do not use essential oils under the nose or in the nostrils.

A

True (can cause toxicity)

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44
Q

True or false. It is okay to heat, microwave or add essential oils to hot water.

A

False

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45
Q

Study the Nasal bulb syringes and NoseFrida on slide 33 & 34.

A

:)

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46
Q

Nasal strips can be used ≥ ____ years old. Some contain menthol. ALL contain latex. One time use.

A

5 yo

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47
Q

intra-nasal aids are latex free and can be used in people ≥ ____ years old.

Which of the following can be used for 15 days?
A. AIR Breathe
B. Brez
C. SleepRight

A

12

C. SleepRight

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48
Q

Decongestants work in the _________ and _______ cavities to relieve congestion

A

sinus, nasal

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49
Q

What are 3 direct-acting decongestants?

A
  1. Phenylephrine (PE)
  2. Oxymetazoline
  3. Tetrahydrozoline
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50
Q
Which of the following is an indirect-acting decongestant? 
A. Phenylephrine (PE)
B. Ephedrine
C. Oxymetazoline
D. Tetrahydrozoline
E. Pseudoephedrine
A

B. Ephedrine

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51
Q
Which of the following is a mixed decongestant? 
A. Phenylephrine (PE)
B. Ephedrine
C. Oxymetazoline
D. Tetrahydrozoline
E. Pseudoephedrine
A

E. Pseudoephedrine

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52
Q

Pseudoephedrine (PSE) has been approved for children ≥ _____ years old.

A

2

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53
Q

What are the 3 different formulations of Pseudoephedrine (PSE)?

A
  1. regular (30 mg q 4-6 h)
  2. 12 hours (120 mg)
  3. 24 h (240 mg)
54
Q

Phenylephrine (PE) has been approved for children ≥ _____ years old.

A

2

55
Q

Is PE as effective as pseudo ephedrine? Why?

A

NO. it has a shorter half-life and undergoes extensive 1st-pass metabolism

56
Q

What dose of PSE can you give to children between 2-5 yo? What is the max dose?

A

15 mg q 4-6 h

MAX: 60 mg

57
Q

What dose of PE can you give to children between 2-5 yo? What is the max dose?

A

2.5 mg q 4 h

MAX: 15 mg

58
Q

What dose of PSE can you give to children between 6-11 yo? What is the max dose?

A

30 mg q 4-6 h

MAX: 120 mg

59
Q

What dose of PE can you give to children between 6-11 yo? What is the max dose?

A

5 mg q 4 h

MAX: 30 mg

60
Q

What dose of PSE can you give to patients older than 12 yo? What is the max dose?

A

60 mg q 4-6 h

MAX: 240 mg

61
Q

What dose of PE can you give to patients older than 12 yo? What is the max dose?

A

10 mg q 4 h

MAX: 60 mg

62
Q

What are the adverse drug effects of systemic decongestants?

A
  1. Cardiovascular stimulation (increases bp, tachycardia, palpitations, arrhythmias)
  2. CNS stimulation (restlessness, insomnia, anxiety, tremors, fear, hallucinations)
  3. Loss of appetite
63
Q

What are some drug interactions with systemic decongestants?

A

MAOIs
TCAs
Antacids

64
Q

Avoid systemic decongestants in which patient populations?

A

patients with uncontrolled bp

elderly

65
Q

Use caution with systemic decongestants in which patient populations?

A

DM (these drugs can cause sugars to go out of whack)
Thyroid disease
Glaucoma
Enlarged prostate
ADHD and ADD (increased risk of CV adverse effects, should recommend another agent for congestion)

66
Q

Can you give a systemic decongestant to a pt who has controlled HTN?

A

Yes, they are generally safe

67
Q

The FDA recommends that OTC cough and cold products NOT be used in pts < ______ years old.

A

2

68
Q

Manufacturers voluntarily restrict the age to > ____ years old to be safer.

A

4

69
Q

The US Combat Meth Act limits sedated to ____ g in 30 days or ____ g per day.

A

9 g

3.6 g per day

70
Q

The Alabama law for sudafed purchases is even stricter than the federal law and says you can get _____ grams in 30 days. Must be ____ years or older.

A

7.5 g

18

71
Q

What is the name of the tamper-resistant formulation of pseudo ephedrine?

A

Nexafed

72
Q

__________ decongestants are used as self-medication for temporary relief of nasal congestion associated with acute or chronic rhinitis, common cold, hay fever, or other upper respiratory allergies.

A

TOPICAL

73
Q

What are some ADEs of topical decongestants?

A
  1. propellant- or vehicle-associated side effects
  2. trauma to the nose from the tip of the device
  3. can cause systemic CB adverse effects
  4. rhinitis medicamentosa
74
Q

What are 2 types of short-acting topical decongestants?

A
  1. Drops (PE) (max use: q 4 h)
    • Neo-synephrine
    • Little Noses (ages 2-6)
2. Inhalers (may contain lavender, camphor +/- menthol)
approved for > 6 yo
Max use: q 2 h
  •Propylhexedrine (Benzedrex)
  • Levmetamfetamine (Vicks VapoInhaler)
75
Q

What are some long acting topical decongestants?

A
1. Xylometazoline
  • lasts 8-10 h
  • Triaminic is not currently available in the US
2. Oxymetazoline
  • Afrin, Dristan, Mucinex, Neo-Synephrine, Sudafed OM, Sinex
  • MANY FORMULATIONS!! 
  • max use: q 12 h
approved for > 6 yo
76
Q

What is rhinitis medicamentosa? How can you prevent it?

A

REBOUND CONGESTION

• restrict topical nasal decongestant therapy to 3-5 days

77
Q

How do you treat rhinitis medicamentosa?

A

Slowly withdrawal topical decongestants
• Replace with topical normal saline
• If needed, intranasal corticosteroids and systemic decongestants can be added
• The mucous membrane returns to normal within 1-2 weeks.

78
Q

Patients with ACUTE COUGH (as well as post nasal drip and throat clearing) associated with the common cold can be treated with:

A

1st gen AH + decongestant

79
Q

Are 2nd gen AH effective at treating patients with the common cold?

A

NO (do not use)

80
Q
[SATA] Which of the following are 1st gen AH?
A. Brompheniramine
B. Loratadine
C. Clemastine
D. Cetirizine
E. Doxylamine
F. Chlorpheniramine
G. Diphenhydramine
A

A, C, E, F, G

81
Q

When should you NOT give a 1st gen AH?

A

in the elderly, due to fall risk and sedation

82
Q
[SATA] Which of the following are only MILDLY sedating?
A. Brompheniramine
B. Promethazine
C. Clemastine
D. Doxylamine
E Chlorpheniramine
F. Diphenhydramine
A

A, E

83
Q
[SATA] Which of the following are HIGHLY sedating?
A. Brompheniramine
B. Promethazine
C. Clemastine
D. Doxylamine
E Chlorpheniramine
F. Diphenhydramine
A

B, C, D, F

84
Q

Beware of ___________ excitatory effect in children and elderly.

A

paradoxical

85
Q
[SATA] Which of the following 2nd generation AH cause minimal - moderate sedation? 
A. Fexofenadine
B. Loratadine
C. Hydroxyzine
D. Cetirizine
E. Levocetirizine
F. Desloratadine
G. Meclizine
A

C, D, E, G

86
Q

2nd generation AH have some ________________ effect and may reduce nasal congestion.

A

anti-inflammatory

87
Q

True or false. It is best to just use single products.

A

TRUE

88
Q

Combo products are usually _____ (more or less?) expensive per dose

A

MORE

89
Q

T/F? Combo products are always correctly dosed.

A

False

90
Q

Patients with ACUTE COUGH due to the common cold, OTC combination cold medications, WITH THE EXCEPTION OF 1ST GENERATION AHs AND DECONGESTANTS, are ______________ until CCTs prove they are effective as cough suppressants.

A

NOT RECOMMENDED

91
Q
The following are all examples of \_\_\_\_\_\_\_\_\_\_\_\_. 
chlophedianol
codeine
dextromethorphan
diphenhydramine
benzonatate
A

Antitussives

92
Q

Guaifenesin is an example of a _____________.

A

Protussive (expectorant)

93
Q

What is Guaifenesin used for?

A

Ineffective productive coughs

94
Q

True or false. The glass of water used to swallow the guaifenesin is just as effective as the med itself.

A

True

*There is no clinical evidence that guaifenesin is effective for acute coughs or colds

95
Q

___________ is not available in the US. It is a centrally acting cough suppressant with AH and anticholinergic properties.

A

Chlophendianol

96
Q

What are some side effects of Chlophendianol?

A

blurred vision
drowsiness
dry mouth
N/V

97
Q

What are some ADEs of codeine?

A

N/V
sedation
dizziness
constipation

98
Q

Drug interactions with codeine?

A

all drugs that cause drowsiness

99
Q

Use caution with codeine because of. . .

A

impaired respiratory reserve

it is excreted in breast milk

100
Q

Review slide 61.

A

:)

101
Q

What drug increases the cough threshold and is only recommended in chronic bronchitis? It has product abuse due to euphoric effect

A

Dextromethorphan

102
Q

What are some ADEs of Dextromethorphan?

A

drowsiness
N/V
constipation

103
Q

Drug interactions with Dextromethorphan?

A

drugs that cause drowsiness, MAOIs

104
Q

What is the only 1st gen AH to have antitussive properties?

A

Diphenhydramine (bendaryl)

105
Q

Which antitussive is Rx only and is thought to inhibit neural activity of sensory nerves in the cough-reflex pathway?

A

Benzonatate

106
Q

What are the side effects of Benzonatate?

A

It is generally free of side effects but it has a variable & unpredictable effectiveness

107
Q

What is the dose for Benzonatate?

A

in > 10 year olds, 100-200 mg TID
MAX: 600 mg/day
*There is no difference in efficacy b/w the 100 and 200 mg dose

108
Q

What drug has been approved for the symptomatic relief of acute, ineffective productive coughs and helps loosen the phlegm and thins the bronchial secretions to make coughs more productive?

A

Guaifenesin

109
Q

What are some ADEs of Guaifenesin?

A
N/V/D
dizziness
HA
rash
drowsiness
110
Q

What are ADEs of local anesthetics?

A

numb mouth and tongue

111
Q

How often can you use a local anesthetic for your sore throat?

A

every 2-4 hours

112
Q

Which of the following formulation dissolves slowly and does NOT need to be chewed?
A. Throat sprays
B. Throat lozenges/lollipops
C. Oral disintegrating strips

A

B. Throat lozenges/lollipops

113
Q

Which of the following formulation needs to sit for 15 seconds and then be spit out?
A. Throat sprays
B. Throat lozenges/lollipops
C. Oral disintegrating strips

A

A. Throat sprays

114
Q

Stop local anesthetics if not better in ____ days.

A

7 (could be strept throat)

115
Q

Review slide 69.

A

:)

116
Q

What type of local anesthetic coats the mucus membrane and relieves irrigation?

A

Demulcents

117
Q

What are some examples of Demulcents?

A

pectin

glycerin

118
Q

NSAIDs, APAP and ASA are all examples of ___________.

A

Systemic Analgesics and Antipyretics

119
Q

NSAIDs, APAP and ASA are effective for ______, _____ and ______.

A

aches, coughs and fevers

120
Q

Honey as a CAM for sore throats, etc should only be used in children older than ___________.

A

12 months

121
Q

When should you use honey as a CAM for sore throats?

A

use 30 min BEFORE bedtime, due to botulism

122
Q
Which of the following soothes sore throats and can help with influenza, sinusitis and bronchitis symptoms? 
A. Honey
B. Elderberry
C. Zinc
D. Vitamin C
A

B. Elderberry

123
Q

Avoid elderberry if you have a ___________ allergy.

A

ragweed

124
Q

Beware of __________ with elderberry.

A

Cyanide toxicity

125
Q
Which of the following as modest antiviral effects and is best if started within 24 h of symptom onset. Do not drink or eat for \_\_\_\_\_\_\_ after you take the dose?
A. Vitamin C, 30 min
B. Elderberry, 10 min
C. Zinc, 15 min 
D. Magnesium 15 min
A

C. Zinc, 15 min

126
Q

Nasal formulations of __________ have been linked to anosmia (loss of sense of smell) and are NOT recommended.

A

Zinc

127
Q

Zinc __________ may have GI side effects.

A

lozenges

128
Q

Doses of vitamin C around _____/day are associated with diarrhea and other GI symptoms

A

4 g

129
Q

T/F. Vitamin C is a fat soluble vitamin.

A

False

130
Q

T/F. There is not hard evidence that vitamin C helps treat a cold. If you are an athelete or a soldier and chronically take Vit C it may prevent your chance of catching a cold.

A

True