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Respiratory Drugs > Cough > Flashcards

Cough Flashcards

1
Q

Mucolytics

A

N-acetylcysteine

Carbocisteine

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2
Q

MOA of N-acetyl cysteine

A

Free sulfhydryl group of NAC breaks disulfide bonds of mucoprotein molecules

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3
Q

Side effects of NAC

A

Nausea and voniting
Stomatitis
Bronchospasm
GI upset

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4
Q

Other use of NAC

A

Antioxidant

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5
Q

NAC iS an antidote for

A

Acetaminophen poisoning

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6
Q

Relief if cough by excessive and tenacious sputum or phlegm

A

Carbocisteine

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7
Q

Carbocisteine reduces ___(1)____ and facilitates ___(2)____

A

1) viscosity of bronchial secretions

2) facilitates expectoration

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8
Q

Expectorants stimulate GASTRIC RECEPTORS through the

A

Vagus afferent nerve

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9
Q

Expectorants at subemetic dose stimulate

A

Bronchial glands to secrete a watery fluid

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10
Q

Abnormality in the ultrastructure of the cilia

A

Cilliary dyskinesia

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11
Q

MOA of expectorants

A

GastroPulmonary MucoKinetic Vagal Reflex

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12
Q

For productive cough

A

Expectorants

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13
Q

For dry, non-productive cough

A

Antitussives

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14
Q

Types of antitussives

A

Peripherally acting
Centrally acting
Antihistamines
Demulcents

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15
Q

MOA of Periperally-Acting Antitussives

A

Works on SENSORY RECEPTORS

Decrease SENSITIVITY of lung parenchymal receptors

Produce COOL SENSATION by stimulating COLD SENSORY RECEPTORS

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16
Q

Increases the threshold for a cough stumulus at the cough center in the medulla

A

Centrally-acting antitussives

17
Q

Centrally-acting antitussives

Natcotics:

A

Codeine
Oxycodone
Hydrocodone

18
Q

Centrally-acting antitussives

Non-Natcotics:

A

Dextromethorphan

19
Q

Overdose of dextromethorphan causes

A

Ataxia

20
Q

Acts centrally by suppressing medullary cough center; anticholinergi activity

A

Diphenhydramine

21
Q

Soothe an irritated throat and bronchial passageway by promoting salivary flow and may produce an antitussive action

A

Demulcents

Respiratory Drugs (4 decks)

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