COTE Peer Teaching Flashcards
List 6 possible causes of falls in elderly people.
- Drugs (sedatives, alcohol)
- MSK eg. OA of hip
- Syncope (vasovagal, cardiogenic, arrhythmias)
- Stroke / TIA
- Hypoglycaemia
- Visual impairment
- Dementia
- Poor environment
What are the 3 main features of Parkinson’s?
- Tremor
- Bradykinesia
- Rigidity (lead-pipe; cog wheel)
List 3 differential features of a Parkinsonian tremor.
- Slow (pill-rolling)
- Worse at rest
- Asymmetrical
- Reduced on distraction
- Reduced on movement
What is the underlying pathophysiology of Parkinson’s?
Loss of dopaminergic neurons in the substantia nigra.
What class of drugs is normally combined with L-Dopa to prevent peripheral side effects? (re: Parkinson’s).
L - Dopa Decarboxylase inhibitor (Carbidopa or Benserazide)
Name 3 complications of L-dopa therapy (re: Parkinson’s patients).
- Postural hypotension on starting treatment
- Confusion
- Hallucinations
- L-dopa induced dyskinesias
- On-off effect: fluctuations in motor performance between normal function (on) and restricted mobility (off).
- Shortening duration of action of each dose (i.e. end-dose deterioration, where dyskinesias become more prominent at the end of the duration of action.
A patient presents with confusion. What should you ask about in their history?
- Premorbid personality
- PMHx
- Medications
- Social circumstances
- Any past similar episodes
Describe ‘dementia’.
- Chronic illness
- Progressive course
- Preserved attention
- Consciousness preserved
- Irreversible
- No underlying medical cause
Describe ‘delirium’.
- Acute onset
- Fluctuating course
- Inattention
- Altered level of consciousness
- Usually reversible
- Associated with underlying medical cause
What causes delirium?
‘DELIRiUM’
- Drug use (introduction, dose adjustments)
- Electrolyte and physiological abnormalities
- Lack of drug (withdrawal)
- Infection
- Reduced sensory input (blind, deaf, changing environment)
- Intracranial problems (stroke, post-octal, meningitis, subdural haemorrhage)
- Urinary retention + faecal impaction
- Myocardial (MI, Arrhythmia, HF)
How would you manage a patient with delirium?
- Treat the cause
- Manage environment
- Soft lighting
- Clocks and calendars
- Sleep hygiene (promote night time sleep)
- Avoid multiple rooms / ward moves
- Minimise provocation
Give a summary of ‘Vascular Dementia’.
- Step-wise progression
- Caused by problems with the blood supply to brain
Give a summary of ‘Alzheimer’s Dementia’.
- Most common type of dementia
- Progressive
- Loss of ability to learn, process and retain new information
What would a patient with Alzheimer’s’ brain look like on CT / MRI?
Atrophic :(
What is the pathophysiology of Alzheimer’s?
- Neurofibrillary tangles
- Loss of neurons
- Aggregation of beta-amyloid plaques