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Gram + Rods > corynebacterium diphtheriae > Flashcards

corynebacterium diphtheriae Flashcards

1
Q

General Properties

A

Reportable

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2
Q

Sources

A

Humans. Colonize nose and pharynx

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3
Q

Transmission

A

Person to person by respiratory droplets

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4
Q

Diseases

A

Myocarditis

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5
Q

Virulence Factors: Viral encoded toxin

A

diphtheria toxin
inactivation of EF2 preventing protein synthesis by ribosome

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6
Q

Prevention

A

Vaccination- dTap and Tdap

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7
Q

Unique Features

A

Thick fibrous pseudomembrane covers pharyngeal epithelium

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8
Q

Virulence Factors- AB toxin

A
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9
Q

Detection

A

Tellurite or Leoffler agar
Test isolate for toxin production by ELEK test or PCR looking for gene

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Gram + Rods (9 decks)

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