Corticosteroids (glucocorticoids)

Question 1

Important side effects of corticosteroids (5)

Answer 1

1. immunosuppression ( nb . reduces eosinophils in blood)
2. Metabolic effects; diabetes and osteoporosis
3. Increased catabolism; proximal muscle weakness, skin thinning, easy bruising, gastritis.
4. Affects mood
5. Mineralocorticoid effects; hypertension, oedema, lowers Potassium.

Question 2

What is the risk of combining steroids with NSAIDs?

Answer 2

GI bleeding

Question 3

What are the adverse effects of inhaled steroids? (2)

Answer 3

1. Oral candidiasis - advise patient to rinse mouth with water to help prevent this.
2. Hoarse voice

Note: can increase the risk of pneumonia with COPD