Coronary Heart Disease: Overview Flashcards

1
Q

How are ventricular tachyarrhythmias caused from transient ischaemia in CHD?

A

Electrical activity is altered by ischeamic heart.
Longer QT interval is produced, ie the re-polarisation state is longer.
This causes more excitation of the myocardium:
Ventricular tachycardia–> V tachyarrhythmia–> MI.

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2
Q

Why does cardiogenic shock occur?

A

Inadequate system perfusion as a result of cardiac dysfunction.
If untreated= 90% mortality.

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3
Q

Where can acute MI often affect?

A

LAD

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4
Q

What is the important clinical diagnosis in CHD patients?

A

Angina

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5
Q

What are the typical descriptions regarding to chest pain in angina?

A

Pain is visceral
Descriptions:
Hard to describe, can be sharp, dull, local or radiating. “elephant on chest”
Gestures- hand/ tight fist on area of chest.

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6
Q

Use part of SOCRATES to explain presentations of Angina

A

S- central or side of chest.
O- on exertion, like exercise
C- can be sharp, pressing, heavy, dull, squeezing
R- can spread to teeth, jaw, neck and down the arms.
A- related to any other signs/symptoms?
T- can be again during exertion, or random
E- exercise or stress can be an exacerbating factor
S- depending on extent to which it is affects daily activities.

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7
Q

What are some differential diagnoses for chest pain?

A
  1. GI- Reflux, burning, acid, waterbrash
  2. Musculoskeletal- localised pain, tender, prolonged, character, exacerbated by moving area.
  3. Pericarditis- central, posture related
  4. Pleuritic - focal, exacerbated by breathing, sharp
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8
Q

What are some emergency diseases associated with chest pain?

A
  1. MI- severe, associated autonomic upset, could be painful even with morphine
  2. Pulmonary embolus- dull to percuss, breathlessness
  3. Aortic dissection- tearing, excruciating
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9
Q

What are some common tests used to confirm CHD?

A
  • CT
  • Exercise testing
  • Angiogram
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10
Q

What are some pros/cons of exercise testing?

A

Pros- cheap, reproducible, + test at low workload= poor prognosis

Cons- Poor diagnostic accuracy in Imp sub-groups
Submaximal testing

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11
Q

What is blood perfusion scanning?

A

Detects area of high and low blood perfusion, to identify the ischaemic part of the heart.

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12
Q

What are some pros/cons of perfusion imaging?

A

Pros- Non invasive, pharmological stress in less mobile patients, Risk stratification

Cons- Radiation, false -/+

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13
Q

What is a CT angiography?

A

CT scan used to look at specific blood vessels, mainly heart vessels.

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14
Q

Pros/Cons of CT angiography?

A

Pros- Non invasive, Anatomical data & risk stratification

Cons- Radiation, Angiogram more precise, especially if Ca present. Cost.

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15
Q

What is angiography?

A
  • Sheath inserted into artery
  • Catheter inserted into arm/groin and moved up, into coronary ostium.
  • X ray dye injected and marks the C arteries
  • Video fluoroscopy records images in multiple views.
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16
Q

Pros/Cons of angiography?

A

Pros- Gold standard, anatomical + risk stratification, follow up angioplasty.

Cons- V rare chance of death, stroke. Radiation
Contrast- renal dysfunction, rash , nausea

17
Q

What are the key factors in reducing risk of CHD?

A
  • Lifestyle
  • Drugs
  • Revascularisation: CABG, PCI
18
Q

What is CABG and PCI

A

Coronary Arterial bypass graft

Percutaneous coronary intervention (stent)

19
Q

What are some common drugs used + function?

A
  1. Aspirin- Anti-platelet
  2. B blocker- slows HR, O2 demand
  3. Statin- reduces cholesterol
  4. ACE inhibitor- reduces BP
20
Q

Main lifestyle interventions?

A
  1. Stop smoking

2. Have healthy diet.

21
Q

What are the main factors of diagnosing CHD?

A

Angina is a clinical diagnosis
Presence of coronary disease can be suggested or confirmed by tests
People may have coronary disease without angina