Coronary circulation Flashcards

1
Q

What do coronary arteries do?

A

Supply myocardium with oxygen

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2
Q

What do cardiac veins do?

A

Drain away deoxygenated blood

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3
Q

Where does circumflex artery come from?

A

Left artery

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4
Q

Where does posterior descending artery come from?

A

Right coronary artery

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5
Q

What is regurgitation?

A

Valve is incompetent - opens in abnormal way

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6
Q

Where does left coronary artery come from?

A

Aorta - left cusp of aortic valve

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7
Q

Where does right coronary artery come from?

A

Right cusp of aortic valve

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8
Q

Coronary arteries

A
  • Right coronary artery (RCA)
  • RCA ostium - 3.2mm
  • Left coronary artery (LCA)
  • LCA ostium - 4mm
  • Anterior interventricular artery (LAD)
  • Circumflex artery
  • Posterior interventricular artery (posterior descending)
  • Right marginal artery
  • Left marginal artery
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9
Q

Left coronary artery

A
  • Usually larger
  • Branches into LAD (comes off very quickly 2cm) (anterior interventricular artery)
  • Left circumflex - left marginal artery is a branch of this
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10
Q

Right coronary artery

A
  • In -85% of people, RCA gives off posterior descending artery, right dominant
  • Right marginal artery
  • Supplies SA nodal artery in 60% of people
  • Supplies atrioventricular nodal branch in 80-90% of people
  • (otherwise may be supplied by left circumflex, left dominant)
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11
Q

Venous drainage of heart

A

Small, middle and great cardiac veins and coronary sinus

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12
Q

What is coronary sinus?

A

Collection of veins draining together, drains blood from myocardium

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13
Q

Conduction in heart

A
  • SAN - heart’s internal pacemaker RA wall initiates cardiac cycle setting rhythm. Electrical impulse spreads to:
  • Atrioventricular node: connected top bundle of His
  • Electrical signals arise in SAN in RA, which stimulates the atria to contract. The signals travel to the AVN (interatrial septum). After a delay, signal diverges and is conducted through L and R bundle of His to respective Purkinje fibres
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14
Q

What does accelerator nerve do in heart?

A

Releases neurotransmitter at SAN to increase HR

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15
Q

What does vagus nerve do in heart?

A

Releases neurotransmitter at SAN to decrease HR

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16
Q

What do carotid bodies do?

A

Chemoreceptors near bifurcation of carotid artery. Detect changes in ppO2 and ppCO2. Send feedback via branches of glossopharyngeal nerve

17
Q

What do aortic bodies do?

A

Chemoreceptors in aortic arch send feedback via afferent branches of vagus nerve

18
Q

What does carotid sinus do?

A

Baroreceptors at base of internal carotid artery, innervated by branch of glossopharygneal

19
Q

What is P?

A

Atrial depolarisation

20
Q

What is QRS?

A

Ventricular depolarisation

21
Q

What is T?

A

Ventricular depolarisation

22
Q

What is the widow maker?

A

Blockage of left main coronary artery

23
Q

What is percutaneous coronary angioplasty?

A
  • Through skin and arteries, find a point that artery is blocked, pass wire across blockage
  • Inflate tube to push plaque against wall
  • Stent holds plaque away
  • Used to open blocked coronary artery, treat stenosis, restore arterial blood flow
  • Coronary catheterisation (visualise vessels on x-ray)
  • Coronary angioplasty
24
Q

What is CABG?

A
  • Take sliver of vein and bypass blockage
  • Can use left internal mammary artery which is diverted to LAD (pedicle)
  • Long saphenous vein is removed from a leg, one end is attached to aorta and the other to the obstructed artery immediately after obstruction
25
Q

Characteristics of cardiac pain

A
  • Shoulder and left arm because sympathetic afferent fibres travel along here to T1-4 of spinal cord
  • Jaw and neck pain too
  • Afferents from vagus (wandering) nerve also carry sensory fibres from heart
  • Vagus nerve synapse in medulla (nucleus tractus solitarius) then descend to excite upper cervical nerve cells (spinothalamic tract) which is felt as neck and jaw pain
  • Neural network between brain, emotion, memory centres and broken heart