Coronary Artery Disease: MOB Flashcards
MOB stands for
Myocardial Oxygen Balance
What is MOB?
The ratio of oxygen supply to oxygen demand
How can we increase Oxygen supply?
-Increase arterial oxygen content
-Increase coronary blood flow:
increase pressure, HR, wall tension, inotropy (muscle contraction)
What is Myocardial Ischaemia?
Develops whern the blood supply to the myocardium is not sufficient to meet metabolic demands. Not enough blood means not enough Oxygen
What is the difference between ‘supply ischaemia’ and ‘demand ischemai’
Supply ischaemai is when the supply < demand = absolute reduction in blood flow at rest
Dmenad ischemai is when the Demand > supply = ok at rest but when demand increases e.g. excercise then supply isn’t sufficient.
What is Myocardial ischamia associated with in most cases?
In >95% of cases, myocardial ischaemia is associated with a critical stenosis which is a serious narrowing of the artery resulting in a significant reduction in maximal flow capacity.
