Coronary Artery Disease Flashcards
What is the etiology of CAD?
HTN (most significant)
Hyperlipidemia
Cigarette smoking
Diabetes
Predictably reproducible, unchanging, consistent over time
precipitated by physical effort
relived by cessation of activity, rest, nitroglycerin
good prognosis
Stable angina
changing character, increase in intensity or frequency, precipitated by less effort, can occur at rest
resolution of symptoms not predictable with methods that previously worked (nitro, rest)
character of blocked arteries is evolving
poor prognosis …impending MI
Unstable angina
How is CAD diagnosed?
- electrocardiogram (ECG)
- exercise stress test
- cardiac catheterization with angiography
Cardiac catheterization with angiography is ___ and ___.
diagnostic and therapeutic
How is CAD treated?
- ID and treat associated diseases that worsen/precipitate angina
- reduction in risk factors for CV disease
- stress management, weight loss, exercise
- pharmacologic management
- revascularization
How can you pharmacolgically manage CAD?
- nitroglycerin
- beta blockers
- anti-platelet therapy
Nitroglycerin is a ___ that decreases cardiac load and oxygen demand. It can be used acutely and ____. What are the 4 different ways it can be administered?
venodilator; prophylactically
- tablet
- spray
- ointment
- transdermal patch
This medication decreases the HR and contractility to reduce the myocardial oxygen demand.
beta blockers
Aspirin (75-325 mg) is an example of this drug that is proven to have a reduction in fatal events and is for all patients.
anti-platelet
What are two examples of surgical revascularization of coronary arteries?
- angioplasty +/- stent
2. coronary artery bypass grafting (CABG)
What are the two types of stents?
- bare metal
2. drug eluting
10 - 50% of ___ ___ stents re-stenos within ___ months
bare metal; 6
These stents release anti-proliferative agents to inhibit re-stenosis.
drug-eluting
Drug eluting stents are at increased risk of ___ for ___ year so patients are placed on ___-____ therapy (aspirin and/or clopidogrel).
thrombosis; 1; anti-platelet