Coronary Artery Disease Flashcards
Ischemia
portion of body that is deprived from sufficient oxygen
Atherosclerosis
define, prognosis, risk factors
build up of plaque along artery walls, narrowing and constricting bloodflow
Prognosis: good with early detetion + treatment
Risk factors:
1. diabetes
2. obesity
3. sedentary lifestyle
4. elevated blood homocystine
5. fibrinogen levels
Caution: 2 or more of the preceding risk factors increase risk of CAD
4 CAD characteristics
- involves a spectrum of clinical entites ranging from angina to infarction to sudden cardiac death
- an imbalance of myocardial oxygen supply and demand resulting in ichemic chest pains
- subacute occlusion may produce no symptoms
- symptoms present when lumen is at least 70% occluded
Angina pectoris
Description, symptoms, duration
- precursor to heart attack
- symptoms: mild to mod. substernal chest pain/ discomfort, pressure or dull ache in chest + L arm, but maybe felt anywehere in UB, including neck,jaw, back, arm, epigastric area
- lasts less than 20 mins.
- increased demand on heart
chest pain inc. in severity, freq, duration=inc. of myocardial infart
or sudden death
stable angina
angina occuring during exercises or activity; relieved with rest and/or sublingual nitroglycerin (meds for angina pectoral is, a vasodilator)
unstable angina
- coronary insufficiency at rest without any precipitating factors or exertion
- pain is difficult to control
Variant angina (Prinzmetal’s angina)
- Caused by vasospsm of coronary arteries in the absence of occulsive disease.
- Responds will to nitroglycerin or calcium channel blocker long term
(vasospastic angina or variant angina) is a known clinical condition characterized by chest discomfort or pain at rest with transient electrocardiographic changes in the ST segment, and with a prompt response to nitrates. These symptoms occur due to abnormal coronary artery spasm.
Myocardial infarction (MI)
- Prolonged ischemia injury
- Death of an area of the myocardium caused by occlusion of one or more of the coronary arteries
- Results in necrosis of heart tissue
S&S of MI
- Severe substernal pain of more than 20 minutes duration which may radiate to neck, jaw, arm, and/or epigastric area.
- Dyspnea, rapid respiration, SOB
- Indigestion, nausea, and vomiting
- Pain unrelieved by rest and/or sublingual nitroglycerin
CAUTION: Pain may be misinterpreted as indigestion
Heart Failure (HF)
- A clinical syndrome in which the heart is unable to maintain adequate circulation of the blood to meet the metabolic needs of the body.
- Caused by CAD, valvlar disease, congenital heart disease, hypertension, infections
Left-sided HF (CHF)
Type of Heart Failure
- blood is not adequately pumped into systemic circulation
- Characterized by pulmonary congestion, edema, and low cardia output due to backup of blood from left ventrical (LV) to left atrium (LA) and lungs
- D/T excessive workload of heart; cardia arrhythmias; or heart damage
Right heart failure
Type of Heart Failure
- blood is not adequately returned from the systemic circulation to the heart
- Characterized by increased pressure load on the right ventricle (RV) with higher pulmonary vasuclar pressures
- D/T LV failure, mitral valve disease of chronic lung disease; produces hallmark signs of jugluar vein distension and peripheral edema
Type of Heart Failure
Biventricular failure
Type of Heart Failure
Severe LV pathology producing backup into the lungs, increased PA pressure, and RV signs of HF
Symptoms of Biventricular Failure
Type of Heart Failure
- Muscle wasting
- Myopathies
- Osteoporosis
Medical Management
- diagnostic procedures (x-ray, ECG, echocardiogram/ultrasound, cardiac stress test and catherterization, pulmary function test)
- Dietary and lifestyle interventions (exercise, low salt/low cholesterol diets, weight reduction, smoking cessation)
- pharmaceutical interventions