Corneal Infiltrative Events (M2) Flashcards
What are the differentials of keratitis?
- bacterial
- fungal
- acanthamoeba
- HSV
- CLPU/CLPI
What are the risk factors for bacterial keratitis?
- age
- male
- smoking
- case hygiene
- internet purchasing
- overnight wear
If a patient has acanthamoeba keratitis are the odds that it is due to CL higher or lower than bacterial?
higher
For which type of keratitis is wearing CLs not a risk factor?
HSV and HZV
Which type for sterile keratitis is usually with daily wear and is bilateral?
CLAIK
Which type for sterile keratitis is usually from overnight wear and unilateral?
CLARE
What are the traits that describe sterile CLPU compared to BK?
- no pain to moderate pain
- watery discharge
- photosensitive to photophobic
- less than 1mm
- peripheral to midperipheral
- midl AC reaction
7 stain area less than infiltrative area - flat to slightly elevated
What are the traits that describe BK compared to CLPU?
- pain
- photophobia
- water to mucopurulent discharge
- diffuse injection
- greater than 1mm
- paracentral to central
- AC reaction with or without hypopyon
- excavated
- lid edema
How can the infiltrates present during acantamoeba keratitis?
- perineural (along the nerves)
2. ring pattern (endstage)
What are the treatments for acanthamoeba keratitis?
- PHMB q2hrs
- Chlorhexidine q2hr
- Propamidine
- steroid with persistent inflammation
What percent of MK patients have a VA loss of 2 lines or greater?
10 to 15%
What are the non modifiable risk factors of MK?
- age
- refractive error (high errors)
- genetic
- gender
- socioeconomic status
What are the modifiable risk factors of MK?
- overnight wear
- lack of hand washing
- smoking
- case age
What are the cases solution related risk factors for MK?
- multipurpose solution (Renu and Complete Moisture Plus)
- topping off
- lack of disinfection
Why does overnight wear lead to increased risk of MK?
- stagnant tear film
- biodurden and biofilm
- hypoxia