Corneal Infiltrative Events (M2) Flashcards

1
Q

What are the differentials of keratitis?

A
  1. bacterial
  2. fungal
  3. acanthamoeba
  4. HSV
  5. CLPU/CLPI
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2
Q

What are the risk factors for bacterial keratitis?

A
  1. age
  2. male
  3. smoking
  4. case hygiene
  5. internet purchasing
  6. overnight wear
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3
Q

If a patient has acanthamoeba keratitis are the odds that it is due to CL higher or lower than bacterial?

A

higher

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4
Q

For which type of keratitis is wearing CLs not a risk factor?

A

HSV and HZV

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5
Q

Which type for sterile keratitis is usually with daily wear and is bilateral?

A

CLAIK

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6
Q

Which type for sterile keratitis is usually from overnight wear and unilateral?

A

CLARE

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7
Q

What are the traits that describe sterile CLPU compared to BK?

A
  1. no pain to moderate pain
  2. watery discharge
  3. photosensitive to photophobic
  4. less than 1mm
  5. peripheral to midperipheral
  6. midl AC reaction
    7 stain area less than infiltrative area
  7. flat to slightly elevated
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8
Q

What are the traits that describe BK compared to CLPU?

A
  1. pain
  2. photophobia
  3. water to mucopurulent discharge
  4. diffuse injection
  5. greater than 1mm
  6. paracentral to central
  7. AC reaction with or without hypopyon
  8. excavated
  9. lid edema
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9
Q

How can the infiltrates present during acantamoeba keratitis?

A
  1. perineural (along the nerves)

2. ring pattern (endstage)

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10
Q

What are the treatments for acanthamoeba keratitis?

A
  1. PHMB q2hrs
  2. Chlorhexidine q2hr
  3. Propamidine
  4. steroid with persistent inflammation
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11
Q

What percent of MK patients have a VA loss of 2 lines or greater?

A

10 to 15%

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12
Q

What are the non modifiable risk factors of MK?

A
  1. age
  2. refractive error (high errors)
  3. genetic
  4. gender
  5. socioeconomic status
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13
Q

What are the modifiable risk factors of MK?

A
  1. overnight wear
  2. lack of hand washing
  3. smoking
  4. case age
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14
Q

What are the cases solution related risk factors for MK?

A
  1. multipurpose solution (Renu and Complete Moisture Plus)
  2. topping off
  3. lack of disinfection
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15
Q

Why does overnight wear lead to increased risk of MK?

A
  1. stagnant tear film
  2. biodurden and biofilm
  3. hypoxia
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16
Q

Are silicone hydrogels more or less likely to cause a CIE? 1. Why? 2

A
  1. 2x more but shorter duration and less severe

2. hydrophobicity inc bacterial adhesion

17
Q

What are the major benefits of daily lenses in relation to MK?

A
  1. lower levels of bioburden
  2. no storage
  3. only handle lens twice
18
Q

Where is fungal keratitis extremely prevalent?

A

developing countries

19
Q

What climate is severe keratitis more likely?

A

warmer, humid regions