Cornea Flashcards
What do the images demonstrate? And what are the highlights?
The normal cornea. Epithelial basement membrane (EBM), Descemet memembrane, endothelium and pre-Descemet membrane layer.
What is this condition? And what are the features demonstrated?
Peters anomaly.
Central corneal opacity, peripheral flattening of the corneal curvature and opacification, and internal ulcer of von Hippel.
What is this condition? And what does histology shows?
Bacterial ulcer.
Acute necrotizing ulcerative keratitis, numerous gram-positive cocci, and scar from healed keratitis.
What condition is this? And what does the histology indicates?
Herpes simplex virus keratitis.
Stromal scarring and vascularization, a granulomatous reaction in the region of Descemet membrane, and a featureless corneal stroma with only rare keratocytes.
What is this condition? And what does the arrow indicates?
Fusarium keratitis and fungal hyphae.
What is this condition? And what does the histology shows?
Acanthamoeba keratitis, and cyst and trophozoite forms.
What type of keratopathy is this? And what do the arrows indicate?
Infectious pseudocrystalline keratopathy.
Crystalloid-appearing stromal infiltrate and gram-positive cocci interposed between stromal collagen lamellae.
What is this condition? And what do the arrows show?
Interstitial keratitis of congenital syphilis and ghost vessels.
What is this condition? And what does the histology shows?
Salzmann nodular degeneration and irregular epithelial thickness and diffuse loss of Bowman layer.
What type of keratopathy is this? And it is composed of what?
Calcific band keratopathy. Calcium deposits.
What is this condition? And what does the histology indicates?
Actinic keratopathy and lightly staining basophilic globules.
What condition is this?
Fibrovascular pannus.
What type of keratopathy is this? And what do the arrows noted?
Pseudophakic bullous keratopathy and subepithelial bullae.
What do the images describe?
A failed penetrating keratoplasty (PK) graft, fibrous down growth, a failed graft following Descemet-stripping automated endothelial keratoplasty (DSAEK).
What condition is described in this? And what do the stains demonstrate?
Corneal blood staining.
Erythrocytic debris and hemoglobin in the corneal stroma and hemosiderin within stromal keratocytes.
What condition is this? And what are the characteristics and highlights?
Epithelial basement membrane dystrophy (EBMD) or map-dot-fingerprint dystrophy.
Wavy lines and dot-like lesions, and folding and thickening of the epithelial basement membrane.
What is this condition? And what does the stain demonstrates?
Reis-Bucklers corneal dystrophy and Masson trichrome stain demonstrate diffuse loss of the Bowman layer, superficial stromal fibrosis, and numerous red deposits.
What type of dystrophy is this? And what is the arrangement of the epithelium?
Thiel-Behnke corneal dystrophy and saw-toothed configuration.
What type of dystrophy is this? And what are the deposited materials?
Lattice corneal dystrophy and eosinophilic material and amyloid.
What is this condition? And what do the arrows and stains represent?
Granular corneal dystrophy type 1.
Eosinophilic deposits and stromal collagen and granular deposits.
What is this condition? And what is the highlight of the other image?
Granular corneal dystrophy type 2 (Avellino) and hyaline deposits at the level of Bowman layer and anterior stroma.
What is this condition? And what are the characteristics and highlights?
Macular corneal dystrophy. And diffusely hazy cornea with focal opacities and mucopolysaccharides in the corneal endothelium.
What type of dystrophy is this? And what features are prominent?
Fuchs endothelial corneal dystrophy.
“Beaten bronze” appearance of Descemet membrane, endothelial cell loss, and numerous guttae.
What type of dystrophy is this? And what is the characteristic?
Congenital hereditary endothelial dystrophy with bilateral corneal clouding and diffuse edema with bullous keratopathy.
What condition is this? And what is the characteristic of the cells?
Posterior polymorphous corneal dystrophy. And overlapping or multilayering of endothelial cells.
What is this condition? And what do each image demonstrate?
Keratoconus. And apical stromal thinning, focal disruption of Bowman layer, intraepithelial iron deposition (Fleischer ring), and rupture of Descemet membrane, with rolled-up edges on either side.
