Core Microbiology - Drug Questions

Question 1

Benzypenicillin, amoxicillin, flucloxacillin

Answer 1

Penicillins (cell wall synthesis inhibitors)

Question 2

Cefuroxime, ceftazidime

Answer 2

Cephalosporins (cell wall synthesis inhibitors)

Question 3

Meropenem, imipenem

Answer 3

Carbapenems (cell wall synthesis inhibitors)

Question 4

Monobactams

Answer 4

Aztreonam (gram -ve activity only) (cell wall synthesis inhibitors)

Question 5

Vancomycin and teicoplanin

Answer 5

Glycopeptides (cell wall synthesis inhibitors)

Question 6

Gentamicin, amikacin

Answer 6

Aminoglycosides (protein synthesis inhibitors)

Question 7

erythromycin and clarithromycin

Answer 7

Macrolides (protein synthesis inhibitors)

Question 8

Clindamycin

Answer 8

Lincosamide (protein synthesis inhibitors)

Question 9

Tetracycline, doxytetracycline

Answer 9

Tetracyline (protein synthesis inhibitors)

Question 10

Linezolid

Answer 10

Oxazolidinones (protein synthesis inhibitors)

Question 11

Trimethoprim

Answer 11

Trimethoprim(DNA Synthesis inhibitor)

Question 12

Nalidixic acid, ciprofloaxcin, levofloxacin

Answer 12

Quinolone and Fluiroquinoles (DNA Synthesis inhibitor)

Question 13

Rifampicin

Answer 13

RNA Polymerase/synthesis inhibitor

Question 14

Colisitn

Answer 14

Gram -ve Plasma membrane agents

Question 15

Daptomycin

Answer 15

Gram +ve plasma membrane agents

Question 16

Treatment of S. aureus (not MRSA)

Answer 16

Flucloxacillin

Question 17

Treatment of Strep pyogenes

Answer 17

Benzylpenicillin

Question 18

Treatment of gram -ve bacilli

Answer 18

Cephalosporins (avoid in elderly)

Question 19

Treatment of anaerobes

Answer 19

Metronidazole

Question 20

Treatment of gram positives (MRSA)

Answer 20

Vancomycin

Question 21

Treatment of most clinically relevant bacteria

Answer 21

meropenem

Question 22

Last line treatment for multi-resistant gram -ves

Answer 22

Colistin

Question 23

What is pseudomonas resistant to

Answer 23

ceftazidime and cerbapenems

Question 24

what is MDR-TB

Answer 24

Multi drug resistant TB

Also have Extremely drug resistant (XDR-TB)

Question 25

What do we use to treat MRSA if resistant

Answer 25

Linezolid as opposed to flucoxacillin

Question 26

Last line treatment for enterbactericaea

Answer 26

Meropenem as opposed to ciprofloxacin

Question 27

AZT

Answer 27

Azidothymidine Anti cancer drug that inhibits HIV Reverse transcriptase inhibitor

Question 28

Zidovudine

Answer 28

Thymine analogue

Question 29

Lamivudine

Answer 29

Cytosine analogue

Question 30

Abacavir

Answer 30

Adenine analogue

Question 31

Tenofovir

Answer 31

Guanine analogue

Question 32

Efavirenz and neviropine

Answer 32

NNRTIs

Question 33

Atanzavir and ritonavir

Answer 33

Protease Inhibitors

Question 34

Enfuvirtide

Answer 34

Fusion inhibitor

Question 35

Raltegravir

Answer 35

Integrates , doesn't cause toxicity

Question 36

Maraviroc

Answer 36

Chemokine receptor agonises, helps treat HIV

Question 37

Hep C treatment

Answer 37

Interferons and ribavarin

Question 38

Acivlovir treats

Answer 38

HSC and VZV | It is a nucleoside analogue (phosphorylated by herpes virus thymidine kinase)

Question 39

Ganciclovir treats

Answer 39

Cytomegalovirus

Question 40

Oseltamavir and zanamavir

Answer 40

Neuraminidase inhibitors treat influenze

Question 41

Ribavarin treas

Answer 41

Hep C and RSV

Question 42

Interferons treat

Answer 42

Hep B/C

Question 43

Polyenes

Answer 43

Nyastin and amphotericin B

Question 44

Terbinafine

Answer 44

Allyamine

Question 45

Clotrimazole

Answer 45

Imidazole

Question 46

Fluconazole, itraconazole, voricaonazole

Answer 46

Triazole

Question 47

Andilafungin

Answer 47

Echinocandin

Question 48

5-fluorocytosine

Answer 48

synthetic cytosine anaologue

Question 49

Griseofulvin

Answer 49

Inhibits fungal mitosis