Core Microbiology - Drug Questions Flashcards

1
Q

Benzypenicillin, amoxicillin, flucloxacillin

A

Penicillins (cell wall synthesis inhibitors)

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2
Q

Cefuroxime, ceftazidime

A

Cephalosporins (cell wall synthesis inhibitors)

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3
Q

Meropenem, imipenem

A

Carbapenems (cell wall synthesis inhibitors)

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4
Q

Monobactams

A

Aztreonam (gram -ve activity only) (cell wall synthesis inhibitors)

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5
Q

Vancomycin and teicoplanin

A

Glycopeptides (cell wall synthesis inhibitors)

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6
Q

Gentamicin, amikacin

A

Aminoglycosides (protein synthesis inhibitors)

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7
Q

erythromycin and clarithromycin

A

Macrolides (protein synthesis inhibitors)

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8
Q

Clindamycin

A

Lincosamide (protein synthesis inhibitors)

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9
Q

Tetracycline, doxytetracycline

A

Tetracyline (protein synthesis inhibitors)

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10
Q

Linezolid

A

Oxazolidinones (protein synthesis inhibitors)

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11
Q

Trimethoprim

A

Trimethoprim(DNA Synthesis inhibitor)

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12
Q

Nalidixic acid, ciprofloaxcin, levofloxacin

A

Quinolone and Fluiroquinoles (DNA Synthesis inhibitor)

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13
Q

Rifampicin

A

RNA Polymerase/synthesis inhibitor

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14
Q

Colisitn

A

Gram -ve Plasma membrane agents

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15
Q

Daptomycin

A

Gram +ve plasma membrane agents

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16
Q

Treatment of S. aureus (not MRSA)

A

Flucloxacillin

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17
Q

Treatment of Strep pyogenes

A

Benzylpenicillin

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18
Q

Treatment of gram -ve bacilli

A

Cephalosporins (avoid in elderly)

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19
Q

Treatment of anaerobes

A

Metronidazole

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20
Q

Treatment of gram positives (MRSA)

A

Vancomycin

21
Q

Treatment of most clinically relevant bacteria

A

meropenem

22
Q

Last line treatment for multi-resistant gram -ves

A

Colistin

23
Q

What is pseudomonas resistant to

A

ceftazidime and cerbapenems

24
Q

what is MDR-TB

A

Multi drug resistant TB

Also have Extremely drug resistant (XDR-TB)

25
Q

What do we use to treat MRSA if resistant

A

Linezolid as opposed to flucoxacillin

26
Q

Last line treatment for enterbactericaea

A

Meropenem as opposed to ciprofloxacin

27
Q

AZT

A

Azidothymidine
Anti cancer drug that inhibits HIV
Reverse transcriptase inhibitor

28
Q

Zidovudine

A

Thymine analogue

29
Q

Lamivudine

A

Cytosine analogue

30
Q

Abacavir

A

Adenine analogue

31
Q

Tenofovir

A

Guanine analogue

32
Q

Efavirenz and neviropine

A

NNRTIs

33
Q

Atanzavir and ritonavir

A

Protease Inhibitors

34
Q

Enfuvirtide

A

Fusion inhibitor

35
Q

Raltegravir

A

Integrates , doesn’t cause toxicity

36
Q

Maraviroc

A

Chemokine receptor agonises, helps treat HIV

37
Q

Hep C treatment

A

Interferons and ribavarin

38
Q

Acivlovir treats

A

HSC and VZV

It is a nucleoside analogue (phosphorylated by herpes virus thymidine kinase)

39
Q

Ganciclovir treats

A

Cytomegalovirus

40
Q

Oseltamavir and zanamavir

A

Neuraminidase inhibitors treat influenze

41
Q

Ribavarin treas

A

Hep C and RSV

42
Q

Interferons treat

A

Hep B/C

43
Q

Polyenes

A

Nyastin and amphotericin B

44
Q

Terbinafine

A

Allyamine

45
Q

Clotrimazole

A

Imidazole

46
Q

Fluconazole, itraconazole, voricaonazole

A

Triazole

47
Q

Andilafungin

A

Echinocandin

48
Q

5-fluorocytosine

A

synthetic cytosine anaologue

49
Q

Griseofulvin

A

Inhibits fungal mitosis