Cord prolapse, abnormal fetal positioning, pre-term labour Flashcards
Pre-term labour is when…
Contraction occurs during pregnancy which can progress to cervical effacement + dilation <37 weeks.
Risk factors for pre-term labour
Maternal factors
- Genital tract infection
- Autoimmune condition
- Diabetes
Uterine/cervical factors
- Congenital uterine abnormalities
- Cervical incompetence
Others
- Antepartum haemorrhage
- Multiple pregnancy
- PROM
What investigations are carried out for pre-term labour in intact membranes >30 weeks
Transvaginal USS for cervical length
2nd line= Foetal fibronectin
Vaginal swab for infections
A foetal fibronectin level ______ indicates a _______ chance of labour
<50ng/mL = unlikely in labour
What two markers are investigated for in premature rupture of membranes
Placental Alpha-microglobulin- 1 (PAMG-1)
Insulin-like growth factor binding protein 1 (IGFBP-1)
Tocolysis is indicated in pre-term labour that is…
Between 26 - 33+6 weeks in NON-ruptured membranes
First line management of pre-term labout in 26- 33+6, non ruptured membranes
Tocolysis
- Nifedipine
What is the second line agent for preterm labour in intact membranes, weeks 25-33+6
Atosiban
Management of ruptured membranes in pre-term labour 26-33+6 weeks
Corticosteroids
- Fetal lung development
_______ should be given at weeks ________ in pre-term labour to reduce the risk of cerebral palsy
Magnesium sulfate IV,
weeks 24-34
- Offer in <30 weeks
- Consider in >30 weeks
In pre-term labour, c-section is indicated if the baby is _______ with a gestational age _____
Breech, <32 weeks
What medication is given in PROM
Erythromycin 250mcg 10 days/ until labour
Antenatal steroids from 24 weeks
At what gestational age is delivery considered for PROM
34 weeks
Extreme preterm is defined as gestation age…
<28 weeks
Medical prophylaxis for preterm labour
Vaginal progesterone (gel/ pessary) - Decreases contraction activity