Antenatal care Flashcards
When does screening for SCD and thalassaemia occur?
At the first booking clinic (<10 weeks)
When does the dating scan occur?
Weeks 10-13+6
When is the pertussis vaccine offered?
16-week antenatal appointment
Anomaly scan occurs at…
20 weeks (18-20+6)
When is Anti-D injections given for Rh- women
28-34 weeks
The combined test for Downs syndrome is done at…
11-14 weeks
The combined test for Downs syndrome is composed of…
Ultrasound for nuchal translucency
Blood tests for
- b-hCG
- Pregnancy associated plasma protein A (PAPP-A)
Nuchal translucency greater than ____ is associated with ______
> 6mm, Downs syndrome
(Elevated/ low) b-hCG is associated with an (increased/decreased) risk of Downs syndrome
Elevated b-hCG = higher risk
(Elevated/ low) PAPP-A is associated with an (increased/decreased) risk of Downs syndrome
Low PAPP-A = greater risk
The triple test for Down syndrome can be carried when?
14-20 weeks
The triple test for Downs syndrome is composed of…
3 bloods
- b-hCG
- Alpha-fetoprotein
- Serum oestriol
(Elevated/ low) alpha-fetoprotein is associated with an (increased/decreased) risk of Downs syndrome
Low alpha-fetoprotein = greater risk
(Elevated/ low) serum oestriol is associated with an (increased/decreased) risk of Downs syndrome
Low serum oestriol = greater risk
The quadruple test for Down syndrome can be carried when?
After 20 weeks
The quadruple test for Downs syndrome is composed of…
4 bloods
- b-hCG
- Alpha-fetoprotein
- Serum oestriol
- Inhibin A
(Elevated/ low) inhibin-A is associated with an (increased/decreased) risk of Downs syndrome
Higher inhibin A= greater risk.
Amniocentesis/ chorionic villus sampling is indicated when risk of Down syndrome is…
> 1 in 150
Amniocentesis/ chorionic villus sampling for Down syndrome can be carried out when?
<15 weeks
What is the most recent development for Downs syndrome screening?
Non-invasive prenatal test
- Detects placental DNA in maternal blood
What test is carried out to see how much fetal blood has passed into the mother’s blood?
Kleinhauer’s test
- Involves adding acid to maternal blood.
- Fetal Hb is more resistant.
- Greater percentage of Hb left= more fetal blood in maternal circulation.
What infections are routinely screened for in the booking clinic?
HIV
Syphillis
Hep B
Pregnant women with BMI >30 should be given _______ to prevent neural tube defects
high dose folic acid 5mg
What type of high risk women are offered more frequent scans in third trimester
Older women
Obese women
Diabetes/ gestational diabetes
Previous growth restriction
