COPD Flashcards
Define emphysema
enlargement of distal airways
destruction of acini
absence of fibrosis
DLCO in emphysema
reduced
Sensitivity of CXR for COPD
not good
Indications for oxygen therapy in COPD
PaO2< 55 or SpO2 < 88%
or
PaO2<90% if pulmonary HT,Polycythemia,heart failure is present
Vaccinations in COPD
influenza
pneumococcal
Indication for LVRS in emphysema
upper lobe predominant emphysema
DD for acute exacerbation of COPD
pneumothorax pneumonia pleural effusion CCF cardiac ischemia pulmonary embolism
Role of antibiotic therapy in Acute exacerbation of COPD
increased dyspnea, sputum volume, and sputum purulence
pts with a need for mechanical ventilation
Components of BODE index
BMI
FEV1
MMRC grading
Exercise tolerance(distance walked in 6 min)
Infections predisposing to asthma
RSV
rhino virus
Drugs that can cause exacerbation of asthma
Aspirin and other NSAID
betablockers
Conditions associated with asthma
Rhinosinusitis polyps OSA obesity vocal cord dysfunction GERD
Definition of reversibility in asthma
Improvement in FEV1 of 12% and 200 cc after 2 to 4 puffs of short acting bronchodilator therapy
Methacholine challange is considered positive if there is a drop in FEV1 of
20%
LTRM should be strongly considered for patients with
aspirin induced asthma