COPD Flashcards

1
Q

Define emphysema

A

enlargement of distal airways
destruction of acini
absence of fibrosis

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2
Q

DLCO in emphysema

A

reduced

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3
Q

Sensitivity of CXR for COPD

A

not good

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4
Q

Indications for oxygen therapy in COPD

A

PaO2< 55 or SpO2 < 88%
or
PaO2<90% if pulmonary HT,Polycythemia,heart failure is present

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5
Q

Vaccinations in COPD

A

influenza

pneumococcal

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6
Q

Indication for LVRS in emphysema

A

upper lobe predominant emphysema

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7
Q

DD for acute exacerbation of COPD

A
pneumothorax
pneumonia
pleural effusion
CCF
cardiac ischemia
pulmonary embolism
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8
Q

Role of antibiotic therapy in Acute exacerbation of COPD

A

increased dyspnea, sputum volume, and sputum purulence

pts with a need for mechanical ventilation

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9
Q

Components of BODE index

A

BMI
FEV1
MMRC grading
Exercise tolerance(distance walked in 6 min)

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10
Q

Infections predisposing to asthma

A

RSV

rhino virus

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11
Q

Drugs that can cause exacerbation of asthma

A

Aspirin and other NSAID

betablockers

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12
Q

Conditions associated with asthma

A
Rhinosinusitis
polyps
OSA
obesity
vocal cord dysfunction
GERD
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13
Q

Definition of reversibility in asthma

A

Improvement in FEV1 of 12% and 200 cc after 2 to 4 puffs of short acting bronchodilator therapy

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14
Q

Methacholine challange is considered positive if there is a drop in FEV1 of

A

20%

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15
Q

LTRM should be strongly considered for patients with

A

aspirin induced asthma

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16
Q

cromolyn is first line for

A

exercise induced asthma

17
Q

mech ventilation principles in asthma

A
large ET tube >7.5
low tidal volume
low RR
prolonged expiratory phase with high inspiratory flow
permissive hypercapnia
18
Q

side effects of SABA

A
tremor 
anxiety
tachycardia
low K+ and Mg+
long QT
mild lactic acidosis
19
Q

adverse effects of ziluton

A

reversible hepatitis

20
Q

risk factors associated with OSAS

A
obesity
nasal block
hypothyroidsm
acromegaly
adenoidal or tonsillar hypertrophy
retrognathia
micrognathia
macroglossia
Vocal cord paralysis
21
Q

DD for daytime sleepiness

A

OSAHAS
Periodic limb movement disorder
narcolepsy
sleep deprivation

22
Q

AHI of more than _______ with symptoms indicates sleep apnea

A

5

23
Q

contraindications to mandibular repositioning devices

A

TMJ dysfunction
bruxism
full dentures
inability to protrude mandible

24
Q

Complications of uvulopalatopharyngoplasty

A

nasopharyngeal stenosis
foreign body stenosis
change in voice
velopharyngeal insufficiency

25
Q

Definition of pulmonary HT

A

sustained elevation of Mean pulmonary artery pressure >= 25 mm Hg at rest

26
Q

Causes of acute PHT

A

Acute PE
Pulmonary edema
ARDS

27
Q

Important clue for hypoventilation syndrome

A

elevated PaCO2

28
Q

ATRIAL septostomy

A

palliative procedure performed in right heart failure

29
Q

drug interactions of PDE5 inhibitors

A

protease inhibitors

nitrates

30
Q

ILDs with expiratory airflow obstruction

A

sarcoidosis

hypersensitivity pneumonitis

31
Q

ILDs associated with smoking

A

DIP
Pulmonary Langerhan cell histiocytosis
Respiratory bronchiolitis-ILD

32
Q

antifibrotic drug

A

pirfenidone

33
Q

Lofgren syndrome

A

arthritis
erythema nodosum
B/L hilar adenopathy