COPD Flashcards

1
Q

Define emphysema

A

enlargement of distal airways
destruction of acini
absence of fibrosis

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2
Q

DLCO in emphysema

A

reduced

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3
Q

Sensitivity of CXR for COPD

A

not good

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4
Q

Indications for oxygen therapy in COPD

A

PaO2< 55 or SpO2 < 88%
or
PaO2<90% if pulmonary HT,Polycythemia,heart failure is present

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5
Q

Vaccinations in COPD

A

influenza

pneumococcal

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6
Q

Indication for LVRS in emphysema

A

upper lobe predominant emphysema

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7
Q

DD for acute exacerbation of COPD

A
pneumothorax
pneumonia
pleural effusion
CCF
cardiac ischemia
pulmonary embolism
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8
Q

Role of antibiotic therapy in Acute exacerbation of COPD

A

increased dyspnea, sputum volume, and sputum purulence

pts with a need for mechanical ventilation

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9
Q

Components of BODE index

A

BMI
FEV1
MMRC grading
Exercise tolerance(distance walked in 6 min)

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10
Q

Infections predisposing to asthma

A

RSV

rhino virus

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11
Q

Drugs that can cause exacerbation of asthma

A

Aspirin and other NSAID

betablockers

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12
Q

Conditions associated with asthma

A
Rhinosinusitis
polyps
OSA
obesity
vocal cord dysfunction
GERD
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13
Q

Definition of reversibility in asthma

A

Improvement in FEV1 of 12% and 200 cc after 2 to 4 puffs of short acting bronchodilator therapy

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14
Q

Methacholine challange is considered positive if there is a drop in FEV1 of

A

20%

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15
Q

LTRM should be strongly considered for patients with

A

aspirin induced asthma

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16
Q

cromolyn is first line for

A

exercise induced asthma

17
Q

mech ventilation principles in asthma

A
large ET tube >7.5
low tidal volume
low RR
prolonged expiratory phase with high inspiratory flow
permissive hypercapnia
18
Q

side effects of SABA

A
tremor 
anxiety
tachycardia
low K+ and Mg+
long QT
mild lactic acidosis
19
Q

adverse effects of ziluton

A

reversible hepatitis

20
Q

risk factors associated with OSAS

A
obesity
nasal block
hypothyroidsm
acromegaly
adenoidal or tonsillar hypertrophy
retrognathia
micrognathia
macroglossia
Vocal cord paralysis
21
Q

DD for daytime sleepiness

A

OSAHAS
Periodic limb movement disorder
narcolepsy
sleep deprivation

22
Q

AHI of more than _______ with symptoms indicates sleep apnea

23
Q

contraindications to mandibular repositioning devices

A

TMJ dysfunction
bruxism
full dentures
inability to protrude mandible

24
Q

Complications of uvulopalatopharyngoplasty

A

nasopharyngeal stenosis
foreign body stenosis
change in voice
velopharyngeal insufficiency

25
Definition of pulmonary HT
sustained elevation of Mean pulmonary artery pressure >= 25 mm Hg at rest
26
Causes of acute PHT
Acute PE Pulmonary edema ARDS
27
Important clue for hypoventilation syndrome
elevated PaCO2
28
ATRIAL septostomy
palliative procedure performed in right heart failure
29
drug interactions of PDE5 inhibitors
protease inhibitors | nitrates
30
ILDs with expiratory airflow obstruction
sarcoidosis | hypersensitivity pneumonitis
31
ILDs associated with smoking
DIP Pulmonary Langerhan cell histiocytosis Respiratory bronchiolitis-ILD
32
antifibrotic drug
pirfenidone
33
Lofgren syndrome
arthritis erythema nodosum B/L hilar adenopathy