Control Of Blood Water Potentail Flashcards

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1
Q

Whta is osmoregution

A

Control of blood water potential bias homeostatic mechanisms

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2
Q

where does osmoregulation kidney

A

nephrons

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3
Q

describe the nephron structure

A

long tubules surrounded by capillaries

renal capsule with glomerulus - at the start of the nephron: cup shaped, surrounds glomerulus
proximal convoluted tubule - series of loops surrounded by capillaries walls, walls made up of epithelial cells with microvilli
loop of Henle - hairpin loop extends from cortex into medulla
distal convoluted tubule - similar to PCT but fewer capillaries
collecting ducts -DCT from several nephrons empty into collecting duct

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4
Q

function of the nephron

A

filter the blood to remove waste and selectively reabsorb useful substances back into the blood

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5
Q

what does urine contain

A

water
dissolved slats
urea
other small substances

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6
Q

what does urine not contain

A

protein and bloods = protein are too large to be filtered out of the blood
glucose = all glucose is absorbed at selective reabsorption in the PCT

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7
Q

how does filtering and reabsorption occur

A

stage 1: ultrafiltration
- occurs due high hydrostatic pressure, water and small molecules are forced out of the glomerulus capillaries into the renal capsule

stage2: selective reabsorption
- occurs in the proximal convoluted tubule
- 85% filtrate gets reabsorbed into blood

stage 3&4: the loop of Henle
- maintains a sodium ion gradient so water can be reabsorbed by the blood

stage 5&6
- water moves out of the distal convoluted tubule and collecting duct to return back to the blood
- the collecting duct then carries the remaining liquid(urine) to the ureter

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8
Q

what is ultrafiltration.

A
  • blood enter kidney via the renal artery at high pressure
  • renal artery divides into the afferent arteriole, then the glomerulus = cause high hydrostatic pressure of the blood
  • water and smaller molecules such eg glucose and mineral ions are forced out of the glomerulus down a pressure gradient into the bowman’s capsule
  • pressure gradient aided by the efferent article leaving the glomerulus being narrower than the afferent arteriole
  • proteins left behind in blood as they are too large
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9
Q

describe selective reabsorption

A
  • glucose re absorbed by co transport from epithelial cells of the proximal convoluted tube to blood capillaries
  • carried out by active transporting Na+ ions creating low Na+ conc in epithelial cells
  • Na+ moved from the PCT lumen by facilitated diffusion, which also brings in glucose
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10
Q

adaptions of proximal convoluted tubule

A

microvilli - large SA for reabsorption
lots of mitochondria - provide ATP for active transport

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11
Q

how is sodium ion gradient maintained by the loop of Henle

A
  • mitochondria in the walls of the cells provide energy to actively transport sodium ions out of the ascending limb out of the loop of henle
  • accumalauition of Na+ outside of the nephron in the medulla lower wp
  • water diffuses out by osmosis into the interstitial space and then the blood capillaries, water reabsorbed into the blood
  • at the base of the ascending limb some Na + are transported out by diffusion
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12
Q

reabsorption of water at the DCT and collecting duct

A
  • water moves out the DCT and collecting duct by osmosis
  • collect duct runs parallel to loop of Henle so ion conc increases as you moe down into medulla
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13
Q

Process of osmoregulation

A
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