Control De La Expresion Genica Flashcards

1
Q

Pasos principales del control transcripcional

A
  • capping
  • splicing
  • poli-A tail
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2
Q

Partes de la expresion genica

A
Nucleo
1. Control transcripcional
2. Control del prosesamiento de RNA
Citoplasma
3.transporte y localizacion del RNA
4. Control traduccional
5. Degradacion del mRNA
6. Activacion de proteina
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4
Q

Que es un gen constitutivo

A

Controlala reparacion, duplicacion y espresion del DNA

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5
Q

Que es un enhanser

A

Un potenciador

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6
Q

Los factores de la transcripcion pueden ser

A

Activadores o respresores

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7
Q

Dominios principales de la transcripcion

A

De union del dna

De activacion de transcripcion

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8
Q

Dominios de union del DNA

A

Helice-giro-helice
Cremallera de leucina
Dedos de zinc
Helice-bucle-helice

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9
Q

Dominios de activacion de transcripcion

A

Acido
Rico en glutamina
Rico en prolina

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10
Q

Cuanto mide la cromatina

A

300nm

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11
Q

Eurocromatina

A

Relajada y expresada

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12
Q

Heterocromatina

A

Compacta y no expresada

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13
Q

Genomic imprinting

A

Genes transcripcionalmente inactivos

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14
Q

Splicing

A

Rompimiento de los extremos 3’ y 5’ porlos spliceosomas

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15
Q

SnRNA y snRNP

A

SnRNA- reconoce la secuencia donde se lleva acabo el empalme

SnRNP-parte del espliceosoma

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16
Q

Funcion del micro RNA

A
Crecimiento celular
Diferenciacion de tejidos
Proliferacion celular
Desarrollo embrionario 
Apoptosis
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17
Q

MiRNA 21

A

Resistencia con agentes quimioterapeuticos

Inhibe CASPASAS apoptosis

18
Q

Caspasas

A

Probocan la apoptosis

19
Q

IRES

A

Internal ribosome entry site

20
Q

Chaperonas

A

Proteinas auxiliares del plegamiento

21
Q

Etiqueta de degradacion

A

Marcaje covalente de ubiquitina

22
Q

Tipos de vectores

A

De clonacion-DNA directo

Y moleculares- plasmidos

23
Q

Vectores de clonacion

A

Amplificar el DNA. De interes

24
Q

Vectores de expresion

A

Expresan DNA de interes

25
Q

Que es un gen regulador

A

Depende de como responden ante las moleculas que controlan su expresion

26
Q

Ejemplo de gen constitutivo y regulador

A

Cons. Cel hepatica

Regul. Neurona