Control and Regulation 2

Question 1

What are precursors?

Answer 1

Initial substrates for the metabolic pathway

Question 2

What are common intermediates?

Answer 2

Compounds which occur at cross-over or branching points in metabolic pathways

Question 3

What is the branching point?

Answer 3

Point at which an intermediate may proceed down one of several alternative pathways, depending on the cell’s needs. Pathways can be selected by altering activity of the enzymes at a branching point.

Question 4

How are metabolic processes controlled?

Answer 4

amount of enzyme
catalytic activity
accessibility of substrate

Question 5

What is the result of negative feedback
and positive feedback

Answer 5

Negative feedback - allosteric inhibition
Positive feedback - allosteric stimulation

Question 6

What are the 6 types of reactions ?

Answer 6

Oxidation-Reduction
Group transfer
Hydrolytic
Carbon bond cleavage
Isomerisation
Ligation requiring ATP cleavage

Question 7

What is energy?

Answer 7

Energy is defined as the capacity to do work.
The more reduced a molecule the more energy it contains
Hydrolysis of ATP releases energy