Contraception and STIs Flashcards

1
Q

IUD mechanism? time until effective? Advantages? Disadv?

A

MECHANISM
Primary mode of action is prevention of fertilisation by causing decreased sperm motility and survival. Also foreign body reaction in the endometrium prevents implantation.
TIME UNTIL EFFECTIVE Immediate
ADVANTAGES Immediate effect, can be used for emergency and long term contraception, not affected by medication

DISADVANTAGES/RISKS
Ectopic pregnancy, HMB, avoid in women with structural disease

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2
Q

IUD complications?

A

Irregular PV bleeding, especially first 3–6mths.
• Risk of infection: screen for Chlamydia prior to insertion.
• IUCD expulsion: most common in the first 3mths after insertion.
• Perforation: poor insertion technique or <4wks post-partum.
• Dysmenorrhoea.

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3
Q

Timing of insertion normally, post-partum, following TOP of IUD

A

I nsert any time during cycle (as long as pregnancy excluded).
• Post-partum: safe to insert IUCD from 4wks after delivery.
• Following TOP: insert within first 48h after termination.

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4
Q

CIs of IUD?

A

P regnancy.
• U ndiagnosed genital tract bleeding.
• A ctive genital tract infection or PID.
• U terine anomalies or fi broids distorting cavity.
• C opper allergy.

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5
Q

How to use IUD as emergency contraception?

A

must be inserted within 5 days of UPSI, or
if a women presents after more than 5 days then an IUD may be fitted up to 5 days after the likely ovulation date

may be left in-situ to provide long-term contraception. If the client wishes for the IUD to be removed it should be at least kept in until the next period

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6
Q

Emergency hormonal contraception choices? Timing? SEs?

A

Levonorgestrel: Must be taken within 72hrs of UPSI
single dose of levonorgestrel 1.5mg (a progesterone)
the dose should be doubled for those with a BMI >26 or weight over 70kg
SEs: Disturbances of current menstrual cycle, vomiting (if occurs within 3hrs then dose should be repeated)
can be used more than once in a menstrual cycle if clinically indicated

Ullipristal = a selective progesterone receptor modulator
Use no later than 120hrs after intercourse
- may reduce the effectiveness of hormonal contraception. Contraception with the pill, patch or ring should be started, or restarted, 5 days after having ulipristal. Barrier methods should be used during this period
- Caution using ullipristal in patients with severe asthma

breastfeeding should be delayed for one week after taking ulipristal. There are no such restrictions on the use of levonorgestrel

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7
Q

Mechanism, time until effective, adv, disadv of mirena coil?

A

MECHANISM levonorgestrel prevents endometrial proliferation and causes cervical mucous thickening
TIME UNTIL EFFECTIVE
7 days
ADVANTAGES
Stays in for 5 years, treats menorrhagia, can be used for HRT in post-menopausal women

DISADVANTAGES/RISKS Initially – frequent uterine bleeding and spotting (first 3-4mnths)
Hormonal symptoms: nausea, headache, breast tenderness, bloating
uterine perforation
PID
expulsion
increased risk of ectopic

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8
Q

How many years can IUS be left in for?

A

the most common IUS (i.e. Mirena® - levonorgestrel 20 mcg/24 hrs) is effective for 5 years
if used as endometrial protection for women taking oestrogen-only hormone replacement therapy they are only licensed for 4 years

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9
Q

Ix for lost threads? Causes? Check?

A
  1. Exclude pregnancy
  2. USS
  3. If ultrasonography cannot locate the device, and pregnancy has been excluded, arrange for an abdominal and pelvic X-ray. – If cannot find on X-ray – its been expelled
    - if it is in abdomen - confirms perforation - arraneg elective laparoscopic removal - offer reinsertion min 4wks after perforation

Causes:

  • Device has moved superiorly into the uterus
  • Pregnancy
  • Perforation
  • Expulsion

After insertion – thread check at 3-4wks

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10
Q

POP mechanism, time until effective, Adv, Disadv?

A

MECHANISM Prevents ovulation, thickens cervical mucus, thins endometrium (prevents implantation)

TIME UNTIL EFFECTIVE
if commenced up to and including day 5 of the cycle it provides immediate protection. If started any other time – use additional contraception for 48hrs after starting pill.
ADVANTAGES
No oestrogen
Can give trial of POP before infection/depot to see how well SEs are tolerated
very effective when taken correctly and is more effective than barrier methods of contraception

DISADVANTAGES/RISKS Irregular menstrual bleeding, other systemic progesterone SEs

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11
Q

Systemic progesterone SEs?

A

Irregular bleeding
Mood swings, low mood, headaches, poor sleep, fatigue
Acne, oily skin
Tender swollen breasts
Food cravings, abdo bloating, Constipation, diarrhoea
Menstrual cramps, decreased libido

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12
Q

When should POP be used over COCP?

A

where COCP is CI - D uring lactation—has no effect on quality or quantity of milk.
• Sickle cell disease.
• SLE and other autoimmune diseases.

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13
Q

POP CIs?

A
P regnancy.
• U ndiagnosed genital tract bleeding.
• S evere arterial disease.
• A ctive hepatic disease.
• H istory of recurrent follicular cysts.
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14
Q

How to switch from COCP to POP?

A

if switching from a combined oral contraceptive (COC) gives immediate protection if continued directly from the end of a pill packet (i.e. Day 21)

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15
Q

Missed POP?

A
Traditional POP  (Micronor, Noriday, Nogeston, Femulen)
if < 3 hours* late: continue as normal
if > 3 hours*: take missed pill as soon as possible, continue with rest of pack, extra precautions (e.g. Condoms) should be used until pill taking has been re-established for 48 hours

Cerazette (desogestrel):
If less than 12 hours late
no action required, continue as normal

If more than 12 hours late (i.e. more than 36 hours since the last pill was taken)
- take the missed pill as soon as possible. If more than one pill has been missed just take one pill. Take the next pill at the usual time, which may mean taking two pills in one day
continue with rest of pack
extra precautions (e.g. condoms) should be used until pill taking has been re-established for 48 hours

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16
Q

Mechanism, time until effective, adv, disadv of implant? SEs?

A

MECHANISM
Inhibits ovulation, also thickens cervical mucus
TIME UNTIL EFFECTIVE
If inserted up to and including day 5 of cycle – no additional contraception required. If not – advise woman to avoid intercourse or use barrier contraception for 7days
ADVANTAGES
Most effective form of contraception, lasts 3 years, no oestrogen, once removed fertility returns

DISADVANTAGES/RISKS Trained professional needed to insert it
systemic progesterone SEs
additional contraceptive methods are needed for the first 7 days if not inserted on day 1 to 5 of a woman’s menstrual cycle

SEs: Menstrual disturbance - amenorrhoea, erratic bleeding - Can be managed with co-prescription of COCP

17
Q

CIs of implant?

A

UKMEC 3*: ischaemic heart disease/stroke (for continuation, if initiation then UKMEC 2), unexplained, suspicious vaginal bleeding, past breast cancer, severe liver cirrhosis, liver cancer
UKMEC 4**: current breast cancer

18
Q

Depo injection Mechanism, time until effective, adv, disadv? SEs?

A

MECHANISM - contains medroxyprogesterone acetate 150mg
Inhibits ovulation
Also cervical mucus thickening and endometrial thinning
TIME UNTIL EFFECTIVE Immediate if 1st injection given up to and including day 5 after start of menstrual bleeding
If not possible - Advise the woman to avoid intercourse or use a barrier method of contraception (such as condoms) for 7 days.
ADVANTAGES
No oestrogen, don’ts have to take a pill every day

DISADVANTAGES/RISKS Missed appointments – degree of user compliance,

SEs:
weight gain,
irregular bleeding
delay in return of fertility (up to a year),
reduces BMD (osteoporosis), systemic progesterone SEs

19
Q

Admin of depo infection?

A

given every 12wks

a pregnancy test should be done if the interval is greater than 12 weeks and 5 days

20
Q

depo injection CIs?

A

breast cancer: current breast cancer is UKMEC 4, past breast cancer is UKMEC 3

21
Q

COCP Mechanism, time until effective, adv, disadv? SEs?

A

MECHANISM
Ovulation inhibition (–ve feedback on hypothalamus + pituitary).
• Thickened cervical mucus preventing sperm penetration.
• Thin endometrium preventing implantation.

TIME UNTIL EFFECTIVe
If inserted up to and including day 5 of cycle – no additional contraception required. If not – advise woman to avoid intercourse of use barrier contraception for 7days

ADVANTAGES
highly effective
doesn’t interfere with sex
contraceptive effects reversible upon stopping
usually makes periods regular, lighter and less painful
reduced risk of ovarian, endometrial - this effect may last for several decades after cessation
reduced risk of colorectal cancer
effective in reducing endometrial problems in PCOS

DISADVANTAGES people may forget to take it
offers no protection against sexually transmitted infections
increased risk of venous thromboembolic disease
increased risk of breast and cervical cancer
increased risk of stroke and ischaemic heart disease (especially in smokers)
temporary side-effects such as headache, nausea, breast tenderness may be seen

may get breakthrough bleeding esp. in first 3mos

22
Q

CIs for COCP?

A
Stroke: Previous stroke
uncontrolled HTN
migraine with aura
obesity
diabetes
IHD
smoking
VTE: 
previous VTE
smoking
obesity
post-partum
known thrombophilia
major surgery with prolonged immobilisation
23
Q

Situations that may reduce COCP efficacy?

A

if vomiting within 2 hours of taking COC pill
medication that induce diarrhoea or vomiting may reduce effectiveness of oral contraception (for example orlistat)
if taking liver enzyme-inducing drugs

24
Q

Missed pill rules for COCP?

A

If 1 pill is missed (at any time in the cycle)
take the last pill even if it means taking two pills in one day and then continue taking pills daily, one each day
no additional contraceptive protection needed

If 2 or more pills missed

  • take the last pill even if it means taking two pills in one day, leave any earlier missed pills and then continue taking pills daily, one each day
  • the women should use condoms or abstain from sex until she has taken pills for 7 days in a row.

if pills are missed in week 1 (Days 1-7): emergency contraception should be considered if she had unprotected sex in the pill-free interval or in week 1

if pills are missed in week 2 (Days 8-14): after seven consecutive days of taking the COC there is no need for emergency contraception*

if pills are missed in week 3 (Days 15-21): she should finish the pills in her current pack and start a new pack the next day; thus omitting the pill free interval

25
Q

List UKMEC 3 conditions for COCP. UKMEC4?

A

UKMEC 3:
more than 35 years old and smoking less than 15 cigarettes/day
BMI > 35 kg/m^2*
family history of thromboembolic disease in first degree relatives < 45 years
controlled hypertension
immobility e.g. wheel chair use
carrier of known gene mutations associated with breast cancer (e.g. BRCA1/BRCA2)
current gallbladder disease

UKMEC4:
more than 35 years old and smoking more than 15 cigarettes/day
migraine with aura
history of thromboembolic disease or thrombogenic mutation
history of stroke or ischaemic heart disease
breast feeding < 6 weeks post-partum
uncontrolled hypertension
current breast cancer
major surgery with prolonged immobilisation

26
Q

COCP admin after pregnancy, TOP?

A

P ost-partum (not breast-feeding): start day 21 after delivery.
Post-termination: within 7 days of termination.

27
Q

Post-partum contraception. IUS? emergency contrception? POP? COCP? implant?

A

IUS can be inserted within 48 hours of delivery, otherwise cannot be inserted until Day 28 due to the risk of expulsion.

Emergency contraception following UPSI is only needed from Day 21 postpartum onwards

COCP should not be used in breastfeeding women as it reduces milk production
POP – can start at any time after pregnancy.
- If started before day 21 postpartum, no additional contraception is required.
- If started after day 21 postpartum, advise the woman to abstain from sex or use a barrier method of contraception for 48 hours after starting the POP, unless she is using the lactational amenorrhoea method (LAM) of contraception

Implant –

  • Insert the progestogen-only implant on or before day 21 postpartum. No additional contraception is required.
  • If the implant is inserted after day 21 postpartum, advise the woman to abstain from sex or use a barrier method of contraception (such as condoms) for 7 days, unless menstruation has started and the implant is inserted on days 1-5.
28
Q

Criteria for Lactational awareness method?

A
  1. Amenorrhoea
  2. fully breast feeding (every 3-4hours day and night)
  3. Less than 6mo post-partum
29
Q

Different ways to give COCP?

A

COCP
transdermal patch
vaginal ring