Contraception Flashcards

1
Q

List the methods of contraception

A
  1. Periodic Abstinence (rhythm method)
  2. Barrier techniques
  3. Spermicides (contain nonoxynol-9 chemical surfactants)
  4. Spermicides-implanted barrier technique (sponge with spermicide)
  5. Hormonal contraception
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2
Q

Disadvantages of male condoms

A

-Efficacy decreased by oil-based lubricants

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3
Q

Absolute contraindications for female condoms

A
  • Allergy to polyurethane

- History of toxic shock syndrome

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4
Q

What is important to remember about female and male condoms?

A

not meant to be used together

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5
Q

Why are spermicides no longer recommended?

A

No added benefit against pregnancy and may increase the risk of HIV transmission

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6
Q

What is important to remember about Diaphragm with spermicide?

A
  • Insert 6 hours before intercourse
  • Leave in place at least 6 hours after intercourse
  • DON’T leave in for >24 hours= risk of Toxic shock syndrome
  • Subsequent acts of intercourse, condom use recommended for additional protection
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7
Q

Diaphragm with spermicide: Absolute contraindications

A
  • allergy to latex, rubber, or spermacide
  • Recurrent UTI
  • History of TSS
  • Abnormal gynecologic anatomy
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8
Q

Diaphragm with spermicide: Advantages

A
  • Inexpensive
  • Decreased risk of cervical neoplasia
  • Some protection against STDs
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9
Q

Diaphragm with spermicide: Disadvantages

A
  • High user error/failure rate
  • Decreased efficacy with increase intercourse frequency
  • Increased vaginal yeast UTIs
  • Efficacy decreased by oil-based lubricants
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10
Q

What is a unique contraindication for Cervical cap (FemCap)?

A

Abnormal papanicolaou smear (due to increased risk for cervical dysplasia)***

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11
Q

What are 2 disadvantages with the cervical cap?

A
  • decreased efficacy in women who have given birth

- Can’t use during menses

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12
Q

In combined hormonal contraceptives, what hormone provides the most contraceptive effect?

A

Progestins

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13
Q

Name the effects progestins have to prevent pregnancy

A
  1. Thickening of cervical mucus
  2. Slow tubal motility (sperm transport)
  3. Induce endometrial atrophy
  4. Progestins block LH surge inhibiting ovulation**
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14
Q

What effects do estrogens have to prevent conception?

A
  • Stabilize endometrial lining to provide cycle control**

- Suppress FSH release from pituitary, contribute to blocking LH surge

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15
Q

Which form of synthetic estrogen is a prodrug?

A

Mestranol

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16
Q

Why would you consider Mestranol?

A

50% less potent than Ethinyl estradiol
so…

if you want less estrogen this one is good

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17
Q

Which is the most common synthetic estrogen?

A

Ethinyl estradiol (EE)

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18
Q

Name a 1st Generation progestin and downside

A

Ex. Norethindrone

  • well tolerated
  • Lower doses have more breakthrough bleeding
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19
Q

Name a 2nd Generation progestin and pros and cons

A

Ex. Levonorgestrel

  • long half-life (IUD*)
  • More androgenic activity - better for libido, worse for hirsutism/acne/lipids
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20
Q

Name 3rd Generation progestin and indication for use

A

Ex. Desogestrel

-Similar to 2nd gen but less androgenic activity–> so think about this in someone with slight libido benefit needed

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21
Q

Name 4th Generation progestin and benefit

A

Ex. Drospirenone (Yasmin)

  • anti-androgenic properties**
  • Advertised for acne
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22
Q

For progestin only, what is importnat to know about the dosing?

A
  • Must take at the same time every day (3 hr window)

- If window missed, need back up contraception for 48 hours

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23
Q

What is a main risk factor for progestin only birth control?

A

Higher risk of ectopic pregnancy

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24
Q

When might be a good time to use progestin only birth control?

A

right after giving birth, because with giving estrogen you would be concerned for increased risk of thrombotic events

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25
Progestin only contraindications:
- Gastric bypass - ischemic heart disease - Rifampin
26
Which type of populations should we be more cautious of for combined oral contraceptives/combined hormonal contraceptives
1. Women older than 35 2. Smokers* 3. Hypertension 4. Dyslipidemia 5. Diabetes 6. Migraine headaches 7. Breast cancer 8. Thromboembolism 9. Obesity 10. Systemic Lupus Erythematosus
27
What does 1 represent on the CDC contraceptives chart?
No restriction
28
What does 2 represent on the CDC contraceptives chart?
Advantages generally outweight theoretical or proven risks
29
What does 3 represent on the CDC contraceptives chart?
Theoretical or proven risks usually outweight the advantages
30
What does 4 represent on the CDC contraceptives chart?
Unacceptable health risk (method not to be used)
31
What are contraindications for CHC?
- Smoker >35 (>15 cigarettes/day) - Lupus - current breast cancer - Severe liver disesase (cirrhosis)/Liver adenoma - High risk of DVT/PE - Migraine headaches with aura - Hypertension - Vascular disease - Post partum <21 days
32
If a patient has no coexisting medical conditions, what oral contraceptive is recommended?
OC containing: 35 mcg or less of EE and less than 0.5mg of norethinodrone (1st gen)
33
How should you alter the OC dose for adolescents, underweight women, women older than 35 and perimenopausal women?
-Lower dose of EE | fewer side effects with 20-25mcg of EE
34
If a patient is nonadherent to her OC what should be considered?
increasing the estrogen dose
35
Which type of oral contraceptive is preferred at initiation of therapy?
Monophasic (not multiphasic)
36
If a patient on oral contraception is having weight gain what can you do?
-this typically improves after 2-3 cycles but can change to a lower estrogentic
37
If a patient has breakthrough bleeding what can you do to the oral contraceptive?
Change to higher estrogenic
38
Name the 5 symptoms that should make you immediately discontinue a combined hormonal contraceptive (CHC)?
ACHES ``` Abdominal pain Chest pain Headache Eye problems Severe leg pain ```
39
How long should someone be on OC before changing/making an adjustment?
2-3 months
40
What is the most common adverse effect of oral contraception?
irregular bleeding | especially first 6 months of extended-cycle regimens
41
Traditionally, when is it recommended for women to start OC?
"sunday start" - first sunday after menstrual cycle begins
42
With starting new oral contraception, how long do you recommend a second method of contraception?
at least 7 days after initiation
43
How long should breast feeding women avoid CHCs?
42 days (w/ risk factors) 30 days (no risk factors)
44
How long should you avoid giving CHCs to a women you just gave birth?
21 days (higher risk of thrombosis)
45
Mirena IUD: Key points
- good for 5 years - Reduces bleeding - 99% effective - Effective 7 days after insertion
46
ParaGard IUD: key points
- copper - Good for 10 years - Off label: emergency contraception - May cause MORE menstrual bleeding** - 99% effective, effective immediately
47
What are the contraindications for ParaGard IUD?
- SLE (with thrombocytopenia) | - Wilson's Disease
48
Nexplanon Implant: key points
- single rod - good for 3 years - 99% effective
49
Nexplanon IUD: contraindications
- cirrhosis | - ischemic heart disease
50
Depo-Provera (DMPA) indications
- sickle cell - older women smokers - seizures
51
Depo-Provera (DMOA) contraindications
currently with breast cancer
52
Depo-Provera: ADE
- Bone loss (should reverse after stoping shots - Weight gain - irregular menses (even after stopping)
53
Transdermal patch: OrthoEvra - key points
- don't wear over breasts - one patch a week for 3 weeks - one week off
54
Transdermal patch: contraindications
Higher risk for VTE
55
How much overlap between pill brands?
none
56
How much overlap needed between pill and patch?
one day overlap
57
How much overlap between pill and ring?
none
58
How much overlap between pill and shot?
1 week
59
How much overlap between pill to implant?
4 days
60
How much overlap from pill to hormone IUD?
1 week
61
How much time can pass between stopping oral pills and starting copper IUD?
5 days
62
If pregnancy already exists and you take emergency contraception- will it harm the embryo?
No
63
Levonorgestrel containing emergency contraception should be taken within what window after unprotected intercourse?
72 hours (3 days)
64
Levorgestrel emergency contraception: primary mechanism of action?
inhibiting or delaying ovulation (doesn't disrupt implantation)
65
What is the window of use for Ulipristal as an emergency contraceptive?
5 days after unprotected sex -Rx only