Contraception Flashcards
Pill - contents
Estrogen + Progestin
Progestin only
Estrogen - ethinyl estradiol
Prevent ovulation by suppressing GnR factors
Prevents FSH and LH secretion
Hepatic metabolism
Progestin - synthetic progesterone-like compound
Suppresses LH
Thickens cervical mucus
Endometrium incapable of implantation
Some hepatic metabolism
Progestin - Drosperinone
Aldosterone antagonism analog
~25 mg spironolactone
Monitor K
Caution with ACEIs and ARBs
Pill - other components
Iron - anemia
Folate - prevent neural tube defects
Pill - Monophasic
Consistent estrogen and progestin dose throughout cycle
Pill - Biphasic
Estrogen/progestin ratio varies one time during cycle
Pill - Triphasic
Estrogen/progestin ratio varies twice during cycle
Pill - Four-phasic
Initial high estrogen - dose red durign proliferative/follicular phase
Initial low progestin - dose increase during secretory/luteal phase
Pill - extended cycle
Monophasic with 84 days active/7 days placebo or 24 days active/4 days placebo
Pill - continuous cycle
No placebo
Pill - drug interactions
rifampin, griseofulvin, phenytoin, phenobarbital, carbamazepine, primidone, ethosuximide, tetracyclin, doxycycline, PCNs, cipro, ofloxacin, telaprevic, tipranavir, elvitegravir
Pill - not recommended for
Women > 35 w/ uncontrolled HTN, DM + vascular dz, smoking
Pill - thromboembolism risks
Protein C/S deficiency
HTN, obesity, DM, smoker, sedentary lifestyle
How long is the patch effective for?
9 days