Contraception Flashcards
what are some risk factors associated with contraceptive methods
Breast cancer: avoid any hormonal contraception and go for the copper coil or barrier methods
Cervical or endometrial cancer: avoid the intrauterine system (i.e. Mirena coil)
Wilson’s disease: avoid the copper coil
what are specific risk factors that should make you avoid the combined contraceptive pill
uncontrolled BP
migrane with aura
H.VTE
35 or above with 15 ciggars
vascular disease or stroke
IHD
Liver cirrhosis or liver tumors
SLE
Major surgery (4 weeks avoid)
In older woman after last period how long is contraception required for age +/- 50.
contraception is required for 2 years in women under 50 and 1 year in women over 50
How long can the COCP be used
The progestogen injection
Up to age 50 and can treat perimenopausal symptoms. DEPO-PROVERA should be stopped before 50 years due to risk of osteoporosis
how long should women who are amenorroheic and taking progestogen only contraception should continue for until the stop (menopause)
FSH blood test results are above 30 IU/L on two tests taken six weeks apart (continue contraception for 1 more year)
55 years of age
When does fertility return after labour and if they using combined pills or P-OP what precautions need to be taken
21 days before fertility,
with COCP- use 7 days condoms
with P-OP use for 2 days
what is the choice of contraception for women under 20 years and what is not recommended
combined and progestogen-only pills are unaffected by younger age
-coils have high rate of expulsion
-Proj-only injection can reduce bone mineral density
-Proj-only implant is a good choice of long-acting reversible contraception
How long is lactation amenorrhea effective for
98% effective form of contraception for 6 months after birth but women must be fully breastfeeding and amenorrhoeic
after childbirth when should the COCP be used and when can the P-OP or implant be started
COCP shouldn’t be started before 6 weeks in women who are breastfeeding
P-OP safe to use any time after birth
what is the time frame for copper coil pr intrauterine system (mirena) used
A copper coil or intrauterine system (e.g. Mirena) can be inserted either within 48 hours of birth or more than 4 weeks after birth (UKMEC 1), but not inserted between 48 hours and 4 weeks of birth (UKMEC 3).
how does COCP prevent pregnancy in 3 ways
Preventing ovulation (this is the primary mechanism of action)
Progesterone thickens the cervical mucus
Progesterone inhibits proliferation of the endometrium, reducing the chance of successful implantation
what affect does oestrogen and progesterone have on the hypothalamus
Oestrogen and progesterone have a negative feedback effect on the hypothalamus and anterior pituitary, suppressing the release of GnRH, LH and FSH. Without the effects of LH and FSH, ovulation does not occur. Pregnancy cannot happen without ovulation.
why would there be ‘withdrawal bleeding’ when COCP in stopped.
The lining of the endometrium is maintained in a stable state while taking the combined pill. When the pill is stopped the lining of the uterus breaks down and sheds. This leads to a “withdrawal bleed“. This is not classed as a menstrual period as it is not part of the natural menstrual cycle. “Breakthrough bleeding” can occur with extended use without a pill-free period.
what are the two type pf COCP
Monophasic pills contain the same amount of hormone in each pill
Multiphasic pills contain varying amounts of hormone to match the normal cyclical hormonal changes more closely
what is the ‘everyday’ formulation and what type of pill is it
Everyday formulations (e.g. Microgynon 30 ED) are monophasic pills, but the pack contains seven inactive pills, making it easier for women to keep track by simply taking the pills in order every day.
Name some monophasic COCP
Microgynon contains ethinylestradiol and levonorgestrel
Loestrin contains ethinylestradiol and norethisterone
Cilest contains ethinylestradiol and norgestimate
Yasmin contains ethinylestradiol and drospirenone
Marvelon contains ethinylestradiol and desogestrel
What type of pill is good to reduce risk of VTE
Levonorgestrel and norethisterone (Microgynon or loestrin)
what is suitable for premenstrual syndrome
yasmin and COCP: Drospirenone
Drospirenone has anti-mineralocorticoid and anti-androgen activity, and may help with symptoms of bloating, water retention and mood changes. Continuous use of the pill, as opposed to cyclical use, may be more effective for premenstrual syndrome.
what is the regime for COCP
21 days on and 7 days off
63 days on (three packs) and 7 days off (“tricycling“)
Continuous use without a pill-free period
what are some side effects and risks
Unscheduled bleeding is common in the first three months and should then settle with time
Breast pain and tenderness
Mood changes and depression
Headaches
Hypertension
Venous thromboembolism (the risk is much lower for the pill than pregnancy)
Small increased risk of breast and cervical cancer, returning to normal ten years after stopping
Small increased risk of myocardial infarction and stroke
what are some benefits of COCP
Effective contraception
Rapid return of fertility after stopping
Improvement in premenstrual symptoms, menorrhagia (heavy periods) and dysmenorrhoea (painful periods)
Reduced risk of endometrial, ovarian and colon cancer
Reduced risk of benign ovarian cysts
give some contraindications for COCP
It is worth noting that a BMI above 35 is UKMEC 3 for the combined pill (risks generally outweigh the benefits).
Uncontrolled hypertension
Migraine with aura (risk of stroke)
History of VTE
Aged over 35 and smoking more than 15 cigarettes per day
Major surgery with prolonged immobility
Vascular disease or stroke
Ischaemic heart disease, cardiomyopathy or atrial fibrillation
Liver cirrhosis and liver tumours
Systemic lupus erythematosus (SLE) and antiphospholipid syndrome