CONTRACEPTION Flashcards
10 Absolute Contraindications for Combined Hormonal Contraception (Estrogen)
• < 4 weeks post partum if breastfeeding
• <21d postpartum (0 breastfeeding)
• Smoker + >35 yo
• HTN (>160/100)
• CVA/CAD
• Valvular disease
• Acute VTE
• Hx of VTE w/ 0 anticoagulants
• Major sx w/ prolonged immobilization
• Thrombophilia
• SLE w/ +/unknown APA
• Current breast CA
• Migraine w/ aura
• DM with retinopathy/neuropathy/nephropathy
• Cirrhosis or liver tumor
4 Absolute Contraindications for Combined Hormonal Contraception (Progestin)
• Unexplained vaginal bleeding
• Current breast CA
• Severe cirrhosis
• Pregnant
3 Risks for Combined Hormonal Contraception
• VTE (3-4 fold increase in risk; AR 1.5/1000)
• MI / Stroke (greater w/ >50mcg)
• Breast CA (minimal)
5 Benefits for Combined Hormonal Contraception
• Menstrual:
o Cycle regulation & ↓ menstrual flow - > ↓Anemia
o ↓Dysmenorrhea / Pelvic Pain
o ↓PMS
o ↓ perimenopausal symptoms
• ↓acne / hirsutism
• ↓risk of ovarian / endometrial CA
• ↓fibroids / benign breast disease / ovarian cysts
5 side effects for Combined Hormonal Contraception
• Irregular Bleeding (1st 3 cycles) (12%)
• Nausea (7%)
• Wt gain (5%)
• Mood (5%)
• Breast Tenderness (4%)
Failure rate for Combined Hormonal Contraception (typical vs. perfect use)
o Typical: 9%
o Perfect Use: 0.3%
Give 3 delivery methods for Combined Hormonal Contraception
Combined oral contraception
Combined patch
Combined Ring
Give 3 examples of combined OCPs and their estrogen levels
Very Low: LOLO 10 mcg
Low: Alesse 20 mcg
Standard: Marvelon, 30 mcg
Give 3 examples of classes of medications that decrease the effectiveness of OCP’s
Anticonvulsants (phenytoin, phenobarbitol)
Antiretrovirals
Antibiotic (only Rifampin)
What is the mechanism of action for combine hormonal contraception?
Prevents ovulation (suppresses gonadotropin secretion)
Prevents implantation (causes endometrial atrophy)
Prevents sperm transportation (causes viscous cervical mucus plug)
Fallopian secretions
List 3 strategies to initiate OCPs
R/o Pregnancy
1st Sunday of Period
If started >/5 days from LMP, use backup x 7 days
Do OCPs: cause cancer, need to take pill breaks, affect fertility, cause birth defects, be used over the age of 35, cause acne?
Does NOT cause cancer
NO need for pill breaks
Does NOT affect fertility
Does NOT cause birth defects
CAN be used over the age of 35
Does NOT cause acne
Describe 2 strategies for continued combined hormonal contraception use and the benefit
Continue combined hormone until breakthrough bleed, then take 4 day break
4 packs (84 days)
Decreases menstrual symptoms
What specific measurement do you take when initiating OCPs?
Blood Pressure
Management if delayed taking OCP in < 24 hrs in ANY week
Take 1 active pill ASAP
Continue taking 1 pill daily until the end of the pack
Management If 1 or more missed pills in first week:
Take most recent pill ASAP (even if it means two pills the same day) and continue taking remaining pills until end of pack
Back up x 7d*
Management If less than 3 pills missed pills during second or third week
Take most recent pill ASAP (even if it means two pills the same day) and continue taking remaining pills until end of pack
start new cycle of OCP without a hormone-free interval
Management if 3 or more consecutive doses/days of OCP missed during second or third week
Take most recent pill ASAP (even if it means two pills the same day) and continue taking remaining pills until end of pack
start new cycle of OCP without a hormone-free interval
Back-up contraception for 7 days
Consider EC
Initiation strategy of Combined Patch (Evra)
R/o Pregnancy
1st Sunday of Period
If started >/5 days from LMP, use backup x 7 days
How is the Combined Patched used, where is it placed, how is it stored, is it okay to shower and exercise with?
1 patch / w x 3 weeks
1 week off
Place on buttocks / deltoid / lower abdomen / upper torso
DO NOT Keep in fridge
Okay for showering / exercise
What is the failure rate of the combined patch? What decreases the efficacy?
Typical: 9%
Perfect Use: 0.3%
Efficacy affected if weight >/ 90 kg
What are 3 side effects of the combined patch (in addition to side effects of combined hormonal contraception)
20% mild local rxn
increased breast tenderness
increased n/v
dysmenorrhea
What is an advantage of the combined patch compared to OCPs other than convenience
Less breakthrough bleeding
How is the Combined Ring (Nuvaring) used, how is it stored?
Insert x 3 weeks
1 week ring free
DONT Store in fridge