Continuation of Lesson 2 Flashcards
is defined asthe smallest, basic unit of life that is responsible for all of life’s processes.”
Cell
the structure in a cell that contains the chromosomes.
Nucleus
threadlike structures made of protein and a single molecule of DNA that serve to carry the genomic information from cell to cell.
Chromosome
is the molecule that carries genetic information for the development and functioning of an organism.
DNA
are made up of sequences of DNA and are arranged, one after another, at specific locations on chromosomes in the nucleus of cells.
Gene
When was the first approved gene therapy case at the National Institute of Health, UK.
1990
Who was the four year girl that has been treated for a genetic defect that left her with an immune system deficiency.
Ashanti DaSilva
What are the Common Genetic Disorder:
Sickle cell
Patau syndrome
Down Syndrome
is a genetic disorder that affects red blood cells. People with this disease produce abnormal red blood cells that are shaped like crescents or sickles, rather than the usual round shape.
Sickle cell
also known as trisomy 13, is a rare genetic condition caused by the presence of an extra copy of chromosome 13. This extra chromosome can disrupt the normal development of various organs and tissues in the body.
Patau syndrome
is a genetic condition caused by the presence of an extra copy of chromosome 21. This extra chromosome can disrupt the normal development of various parts of the body.
Down syndrome
of mutated gene that causes disease with a healthy copy if the gene.
Replacement
of a mutated gene that is functioning improperly.
Inactivation
a new gene into the body to help fight a disease.
Introducing
What are the basic process of DNA
Replacement
Inactivation
Introducing
A type of experimental treatment in which foreign genetic material ( DNA or RNA) is inserted into a person’s cells to prevent or fight disease. It is being studied in the treatment of certain types of cancer or diseases. It involves altering genes inside your body’s cells in an effort to treat or stop a disease.
Gene therapy
Obtaining blood cells with a genetic disease then introduce a normal gene into the defective cell Has to be done several times because the effects does not last long, can’t pass to the next generation.
Somatic Gene therapy
Involves genetic modification of the gametes (reproductive cells, the egg cells and the sperm cells) that will pass to the next generation Can be done once because it is permanent.
Germline Gene Therapy
vehicles that delivers the gene to the cells
Vectors
have the natural ability to deliver genetic materials into cells.
Viruses
inserts its genetic code directly into the chromosomes of the host cell
Retrovirus
introduce the deoxyribonucleic acid (DNA) they carry to the nucleus but not into the chromosomes
Adenovirus
outside the living, cells are modified outside the body and then transplanted back again.
Ex Vivo
inside the living, vector can be injected or given intravenously (IV) directly to the specific tissue in the body
In Vivo
are the mother cells that have the potential to become any type of cell in the body. They have the ability to self-renew or multiply.
Stem Cell
cells that are self-replicating, derived from human embryos or human petal tissue and able to differentiate into 3 primary germ cell layers, and into any type of cell in the body
Embryonic Cells
Any cell of the body except sex cells. Can differentiate only into different cell types present in the tissue of their origin
Somantic Cells
What is the inside of Cells
Nucleus
What is the inside of Nucleus
Chromosome
What is the inside of Chromosome
DNA
What is the inside of DNA
Gene (Segment of DNA)
