Contact Dermatitis Exam 3 Flashcards
Characterized by inflammation, redness, burning, itching, and pustule formation on skin
Contact Dermatitis
2 Types of Contact Dermatitis
Irritant Contact Dermatitis (ICD)
Allergic Contact Dermatitis (ACD)
Inflammatory reaction due to exposure to irritant substances
Irritant Contact Dermatitis (ICD)
Immunologic reaction caused by exposure to an antigen
Allergic Contact Dermatitis (ACD)
Mechanisms of ICD`
Disruption of skin barrier
Changes in cells of epidermis
Release of pro-inflammatory cytokines
Most commonly affected areas are __________ (often due to exposure)
Hands and face
______ % of cases have hand involvement
80%
Existing skin conditions ____________ can result in worse cases of ICD
Atopic Dermatitis
Can effect individuals of any age
Infants and elderly more at risk due to ________
thinner epidermal layers
________ can play a role in type of exposure
occupation
Substances associated with ICD
Strong acids (hydrochloric, sulfuric) Strong bases (sodium, potassium) Detergents, soaps Fiberglass Oils Urine/feces Wood dust
Clinical Presentation of ICD
Inflammation and swelling Itching and burning Rash Hyper/hypo-pigmentation Scaling of skin, dryness
Goals of Therapy ICD
Remove the offending agent
Relieve inflammation and irritation
Educate patient on prevention and treatment
Non-Pharmacologic Therapy for ICD
Flush area with tepid water and mild soap
Non-Pharmacologic Prevention for ICD
Wear protective clothing
Use of emollients and barrier creams
Pharmacologic Treatment Options
Emollients
Colloidal Oatmeal Baths
Topical Corticosteroids
Immunologic reaction caused by allergen-specific T lymphocytes
Allergic Contact Dermatitis (ACD)
T cells migrate to site of contact and release inflammatory mediators
Allergic Contact Dermatitis (ACD)
ACD requires ________
sensitization
Induction Phase of ACD
Immune system sensitized by first exposure to antigen
Elicitation Phase of ACD
Cell-mediated, type IV delayed hypersensitivity reaction
Rash and symptoms typically appear within 24-48 hours, can take days
Epidemiology of ACD is frequency based on exposure such as
Occupation
Hobbies/Habits
Regional allergens
Epidemiology of ACD affects all ages, races and sexes and usually start to see around ______ years old
2-3 years old
Clinical Presentation of ACD
Localized to site of skin contact with allergen
Symptoms may not appear for hours to days
delayed hypersensitivity with ACD
Symptoms of ACD
Severe itching Rash (skin red, swollen, and hot) Excessively dry skin Fluid-filled blisters Oozing blister that leave crust or scales
Substances Associated with ACD
Poison Ivy, Oak, Sumac Metal (Nickel) Lanolin Latex Neomycin Rubber Fragrances Adhesives
Among most common causes of ACD
Poison Ivy, Oak, Sumac
Dermatitis reaction is caused by exposure to
urushiol
urushiol can only be released through damage to the
plant