CONSTIPATION AND IBS Flashcards

1
Q

laxatives (bulk forming type)

cause elimination of soft semisolid stools

A

helps distend colon & stim peristalsis

wheat bran
psyilium husk
isapughula husk
semisyenthetic cellulose

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2
Q

osmotic type

A

cause inc in fecal fluid causing inc. stoll liquidity

lactulose
sorbitol

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3
Q

lubricant type

A

retard water from leavng the stool thus softening it

liquid paraffin

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4
Q

surfactant type

A

allow water, lipid to penetrate the stool softening it

docusate sodium

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5
Q

purgative type

osmotic

A

prompt bowel evacuation byrapid water movement into small intestines and colon giving high volume of liquid stools

magnesium salts
polyethylene glycol

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6
Q

irritant type

A

anthraquinone
hydrolysed in colon giving bowel movement
senna
cascara
aloe

organic irritants
phenolphtalein
bisacodyl
sodium picosulfate

oil type
castor oil that becomes ricolinic acid

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7
Q

bisacodyl ADR

A

allergy reaction
Steven-Johnson syndrome
mucosal damage
inflammation

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8
Q

senna ADR

A

skin rash
brown pigmentation of colonic mucosa
urine disolouration
colonic atony in chronic use

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9
Q

senna ADR

A

skin rash
brown pigmentation of colonic mucosa
urine disolouration
colonic atony in chronic use

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10
Q

Magnesium salt ADR

A

nausea
mild abdominal cramps
unpleasant taste

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11
Q

lactulose ADR

A

flatulence
cramp
nausea

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12
Q

bedridden patients

A

prevent constipation (4 class of laxatives)
psyilium
lactulose
liquid paraffin
docusate

treat constipation
bisacodyl
senna
soap water/ glycerine enema

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13
Q

functional constipation

A

senna
bisacodyl
dietary fibre

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14
Q

post-operative patients

A

psyilium
lactulose
docusates

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15
Q

bowel prep

A

mg sailts
senna

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16
Q

IBS DRUGS

A

antidiarrheal–antispasmodis
dicyclomine
loperamide
diphenoxylate
fedotozine
hyoscyamine
mebeverine

antidepresants
amitriptyline
desipramine

5–HT3 antagonist
alosteron

chlofide channel activators
lubiprostone

miscellaneous
clonidinw
buspirone
loxiglumide
sumatriptan
methylnaltrexone
alvimopan