ANTIPSYCHOTIC DRUGS

Question 1

typical antipsychotics

Answer 1

high potency
haloperidol
fluphenazine
trifluoperazine
prochloperazine

low potency drug
chlorpromazine
thiothixene
thioridazine

Question 2

treat parkinsonism (EPS)
& perioral tremors (rabbit’s syndrome)

Answer 2

antimuscarinic drug’
triHexyphenidyl
procyclidine
benzatropine

Question 3

clozapine

Answer 3

agranulocytosis
paradoxical hypersalivation
risk of diabetes
weight gain
low seizure threshold

Question 4

risperidone

Answer 4

hyperprolactinaemia
EPS at high dose
weight gain
postural hypotension

Question 5

oolanzapine

Answer 5

few EPS
weight gain
risk of hyperlipidemia
new onset of DM and seizures

Question 6

ziprasidone

Answer 6

QT prologation

Question 7

quetiapine

Answer 7

interaction with macrolides, antifungal, aniconvulsants
weight gain
drowsiness
orthostatic hypotension

Question 8

non-psychotic conditions

Answer 8

intracable hiccups
chlorpromazole

antiemetic
prochlorperazine

pruritis
promethazine

pre operative sedative
droperidol + fentanyl

Question 9

good of
CLOZAPINE

Answer 9

efficacy in refractory case
inc suicide risk in schizophrenia

Question 10

treat acute mania, bipolar disorder

Answer 10

olanzapine

aripiprazole

Question 11

aripiprazole ADR

Answer 11

prolonged QTc interval
EPS
weight gain
hyperglycaemia
hypotension