consolidation lectures Flashcards
which antithyroid drug is used in pregnancy?
PTU
radioiodine may worsen…
thyroid eye disease
managmenet of thyroiditis ?
- NSAIDS
- Beta blockers
- steroids
- may need replacement if they become hypo
initial treatment of graves disease?
Carbimazole - if unsuccesful then go to radioiodine or surgery after 18 mo trial
initial treatment of toxic multinodular goitre?
radioidine therapy
what usually precipitates a thyrotoxic storm?
trauma, infection, other stressors in the setting of underlying thyroid problem
management of thyrotoxic storm
- call for help
- ABC
- anti-pyrtics and cooling blankets
- beta blocker
- PTU
- potassium iodide
- corticosteroid
- address underlying cause
What is the active form, T4 or T3?
T3
why is PTU preferred for treating thyroid storm over carbimazole?
PTU prevents peripheral conversion of T4 to T3
pres of myxoedema coma
-CNS - altered status, confusion, coma Hypothermia Bradycardia Lethargy Hypoventilation Seizures Generally unwell Transudates (pleural effusion, ascites, pericardial effusion)
acute management of severe hypercalcemia?
IV fluids
calcitonin
bisphosphonates
primary hyperPTH is most commonly caused by…
an adenoma
what type of anemia is seen in thalasemia?
microcytic
indications for blood transfusion?
- hemodynamically unstable
- <8 hb in stable patient
- active hemorhage
- trauma
what causes pseudo cushings?
- alcohol excess
- major depressive disorder
- primary obesity