Conrad Flashcards
1 -
AMOVA
Analysis of Molecular Variance based on F stats
Haplotype
is a group of alleles in an organism that are inherited together from a single parent – identical in sequences!
Genotype
is the part of the genetic makeup of a cell, and therefore of any individual, which determines one of its characteristics (phenotype)
As distances between sampling sites increase, the genetic differences expressed as FSt also increase = genetically isolated by distance (IBD)
VT
Total Genetic Variance -represents the total genetic variability in the entire population, encompassing both within-population variation and between-population variation.
VS
Within-Population Genetic Variance - measures the genetic variation within each individual population. It reflects the diversity of alleles within populations.
VST
Between-Population Genetic Variance - reflects the genetic differentiation among populations. It quantifies how much genetic variation exists between populations compared to within populations.
FST measures
Variation within populations AND variation between populations
High Fst
mtDNA (variable markers)
Low Fst
Nuclear genes with low genetic variability
Fst equation
VBP-VWP// VBP
H = heterozygosity - calculated by using allele frequencies “p” derived from HW equilibrium – and it is the sum of the allele frequencies
FIT
inbreeding coefficient of individuals relative to the total population
FIS
Inbreeding coefficient of individuals relative to the subpopulation
FST
the proportion of the total genetic variance contained in a subpopulation (the S subscript) relative to the total genetic variance (the T subscript) (NEED RANDOM MATING TO MEET THE CRITERION)
