Connective tissues Flashcards

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1
Q

What is the structure of the subcutaneous layer?

A

Loose connective tissue attached to underlying bone and muscle

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2
Q

What is the function of the subcutaneous layer?

A

Supplies skin with vessels, nerves, fibroblasts, adipocytes, macrophages; contains half the body’s stored lipids

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3
Q

What are loose connective tissues?

A

Adipose and reticular tissue

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4
Q

What are dense connective tissues?

A

Blood, bone, cartilage, muscle and nervous tissue

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5
Q

What are chondrocytes?

A

Cartilage cells, which produce collagen and proteoglycans, to maintain cartilage ECM

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6
Q

Describe the structure of cartilage.

A

Chondrocytes in a matrix, surrounded by collagenous pericondrium. No blood vessels or nerves.

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7
Q

Where is hyaline cartilage found and what is is it for?

A

Sternum, trachea, bronchi, ribs, synovial joints.
For support and flexibility.
Contains evenly dispersed collagen.

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8
Q

Where is elastic cartilage found and what is it for?

A

Larynx, epiglottis, ear, auditory canal.

For support and elasticity.

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9
Q

Where is fibrocartilage found and what is it for?

A

Knees, pelvis, intervertebral discs.
Resists compression, movement and bone-bone contact.
Contains thick bundles of collagen.

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10
Q

What does an osteoblast do?

A

Forms bone, secretes Type I collagen and HA

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11
Q

What does an osteoclast do?

A

Destroy bone by secreting acid

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12
Q

What is the structure of an osteoclast?

A

Large, multinucleated, macrophage like, derived from monocytes in bone marrow

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13
Q

What is an osteocyte?

A

An osteoblast suspended in the bone matrix, has long cell processes which communicate with other cells at gap junctions

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14
Q

Describe the structure of an osteon (Haversian system).

A

Blood vessels + lamellae + osteocytes

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15
Q

What are the names of the transverse and longitudinal canals that connect osteons?

A

Haversian (longitudinal) and Volkmann (transverse) canals.

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16
Q

What is the role of vitamin A in bone formation?

A

Stimulates osteoblast activity

17
Q

What is the role of vitamin C in bone formation

A

Stimulates production of collagen

18
Q

What is the role of vitamin D in bone formation?

A

Stimulates Ca2+ absorption

19
Q

Describe the function of calcitonin.

A

Released from thyroid gland in response to high blood calcium. Causes:

  • Increased excretion of calcium from the kidneys
  • Calcium deposition in bone
20
Q

Describe the function of PTH.

A

Released from parathyroid gland in response to low blood calcium. Causes:

  • Increased reabsorption of calcium by the kidneys
  • Calcium release from bone
  • Increased calcitriol production
21
Q

What is the function of calcitriol?

A

Increased Ca2+ absorption of calcium by the digestive system

22
Q

What are lamellae?

A

Concentric rings of lamellar (compact) bone

23
Q

What are the two types of bone?

A

Lamellar (compact) bone and spongy (cancellous) bone. Cancellous bone is found at the ends of long bones, and lamellar at the shafts.

24
Q

Which types of collagen are found in cartilage and in bone?

A

Type II and Type I respectively.