Connective Tissues Flashcards
Fibroblasts
A large flat cell that secretes collagen, proteins, and fibers to maintain the framework (extracellular matrix and ground substance) of connective tissue in the body. (These are the usually the most numerous in connective tissues.)
Macrophages
These cells have an irregular shape with short branching projections. They play a vital role in consuming cellular debris and bacteria in a process called phagocytosis.
Plasma cells
Plasma cells secrete antibodies (proteins that attack or neutralize foreign substance in the body). They are an important part of the immune system. Mainly found in connective tissues. Also abundant in salivary glands, lymph nodes, the spleen, and bone marrow. (type of white blood cell)
Mast cells
Abundant alongside the blood vessels that supply connective tissue. They produce histamine, a chemical that dilates small blood vessels as a part of an inflammatory response, the body’s reaction to injury or infection. They can also bind to, ingest, and kill bacteria.
Adipocytes
Connective tissue cells that store triglycerides (fats). They are found deep to the skin and around organs such as the heart and kidneys.
Leukocytes
Not normally found in significant numbers in connective tissue however, in response to certain conditions they migrate from blood into connective tissue. (white blood cells)
Ground substance
the component of a connective tissue between the cells and fibers. The ground substance may be fluid, semifluid, gelatinous, or calcified. it supports cells, binds them together, stores water, and provides a medium of exchange of substances between the blood and cells.
Cartilage
dense network of collagen fibers and elastic fibers firmly embedded in chondroitin sulfate (a gel-like component of the ground substance). Can endure more stress than loose connective tissues. It has no nerves or blood cells in its extracellular matrix.
Chondrocytes
The only specialized cell type found in cartilage. They produce collagen and the extracellular matrix found in cartilage. They are only found in the lacunae in the extracellular matrix.
Areolar connective tissue
(loose connective tissue) one of the most widely distributed connective tissues; consists of fibers (collagen, elastic, reticular) and several kinds of cells (fibroblasts, macrophages, plasma cells, adipocytes, mast cells, and a few white blood cells, embedded in in a semifluid ground substance.
Location: in and around nearly every body structure
Function: Strength, elasticity, support.
Adipose connective tissue
(Loose connective tissue) has cells derived from fibroblasts that are specialized for storage of triglycerides (fats) as a large centrally located droplet. Cells fill up with a single, large, triglyceride droplet and cytoplasm and nucleus are pushed to the periphery of the cell. Most adipose tissue in adults is white adipose tissue (just described). Brown adipose tissue is darker due to higher blood supply and is found in fetus and infants (adults have a smaller amount).
Location: wherever areolar connective tissue is located.
Function: reduces heat loss through skin, serves as energy reserve, supports and protects organs.
Blood
blood plasma and formed elements: red blood cells. white blood cells (leukocytes), platelets.
Location: within blood vessels (arteries, arterioles, capillaries, venules, veins.) within chambers of heart.
function: red blood cells: transport oxygen. and some carbon dioxide. White blood cells: carry on phagocytosis and mediate allergic reactions and immune system responses. platelets: essential for blood clotting.
Bone
compact and spongey bone tissue.
location: both types of bones make up various parts of bones of the body.
Function: support, protection; houses blood-forming tissue; serves as lever that act with muscle tissue to enable movement.
Collagen fibers
very strong and resist tensions, but are not stiff which allows tissue flexibility. Collagen fiber properties vary from tissue to tissue. They normally occur in parallel bundles. They are primarily made up of the protein collagen. (found in most types of connective tissues, especially bones, cartilage, tendons and ligaments.
Elastic fibers
Smaller in diameter than collagen fibers, branch and join together to form a fibrous network within a connective tissue. Elastic fibers are strong but can be stretched to 150% of their relaxed length without breaking. They can also return to their natural state after being stretched a property known as elasticity. Plentiful in skin, blood vessel walls, and lung tissue.