Connective Tissue - Notes Flashcards
What is connective tissue proper?
Soft tissues; components in a fluid or gelatinous ground substance
What are examples of soft connective tissues?
Adipose
Blood
What are supportive connective tissues?
Hard tissues: components embedded in a solid ground substance
What are some examples of supportive connective tissues?
Bone
Cartilage
Classification of connective tissue is based on what two things?
Relative density of components
Characteristics of the extracellular matrix
What makes up extracellular matrix?
Ground substance + fibers
What are the 3 components of connective tissues?
Fibers
Ground substance
Cells
What are the 3 types of fibers found in connective tissue?
Collagen fibers
Elastic fibers
Reticular fibers
What do subtypes of connective tissue depend on?
Types and arrangements of fibers
What percent of total body protein is collagen fiber?
30-40%
Are collagen fibers capable of stretching or contracting?
No
Which type of fibers are heat labile?
Collagen fibers
What does heat labile mean?
With heat, collagen fibers become gelatinous and glue-like
Do collagen fibers have a high or low molecular weight?
High
Collagen fibers are composed primarily of which three amino acids?
Glycine
Proline
Hydroxyproline
What is the most abundant amino acid in collagen fibers?
Glycine
What is the monomer of collagen fiber called?
Tropocollagen
Are collagen fibers straight or wavy?
May be either
What determines whether collagen fibers are loosely or densely packed?
Location and function requirements
What is the most common type of collagen?
Type I
What is type II collagen?
Makes cartilage
Where is type III collagen found?
Smooth muscle Aorta Uterus Spleen Lungs
Where is type IV collagen found?
Basal lamina
In the basal lamina, what is the specific location where type IV collagen is found?
Between epithelial and connective tissues
Where is type V collagen found?
Placental membranes
What are the 2 main features of elastic fibers?
Stretch
Resistant to heat
In elastic fibers, what surrounds the elastin?
Microfibrils
Elastin proteins are rich in which amino acids?
Glycine
Proline
Also contains: Valine, desmosine and isodesmosine
Reticular fibers are usually found where ___ is found.
Collagen