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OS 201 Exam 1 > Connective Tissue > Flashcards

Connective Tissue Flashcards

1
Q

Principal cell of connective tissue

A

Fibroblast

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2
Q

Produces matrix

A

Fibroblast

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3
Q

Abundant along the course of blood vessels

A

Adipose cells

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4
Q

Pluripotent connective tissue cell

A

Mesenchymal cell

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5
Q

Irregular surface cytoplasm

A

Macrophage

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6
Q

Deployed along collagen fibers

A

Fibroblast

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7
Q

Rarely divide in normal connective tissue

A

Fibroblast

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8
Q

Enumerate the fixed connective tissue cell

A
  1. Fibroblast
  2. Macrophage
  3. Adipose cells
  4. Mesenchymal cells
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9
Q

Enumerate the free cells

A
  1. Lymphocytes
  2. Plasma cells
  3. Eosinophils
  4. Mast cells
  5. Basophils
  6. Neutrophils
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10
Q

Cells that produce antibodies

A
  1. B lymphocytes

2. Plasma cells

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11
Q

Oval with eccentric nucleus

A

Plasma cells

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12
Q

Fusiform cells

A

Fibroblast

Mesenchymal cells

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13
Q

Responsible for cell mediated immunity

A

T-lymphocytes

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14
Q

Responsible for humoral immune system

A

B lymphocytes

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15
Q

Responsible for humoral immune system

A

B lymphocytes

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16
Q

Programmed to kill virus infected cells and tumor cells

A

Natural killer cells *similar to macrophage

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17
Q

Derived from B lymphocytes

A

Plasma cells

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18
Q

Round with bilobed nucleus and pink coarse cytoplasmic granules

A

Eosinophils

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19
Q

Eccentric bean shaped nucleus

A

Monocytes

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20
Q

Large ovoid with spherical nucleus

A

Mast cells

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21
Q

Basophilic granules contain histamine, heparin and eosinophilic chemotactic factor

A

Mast cells

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22
Q

Where is mast cell located?

A

Mucous membrane and skin

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23
Q

Abundance of Fc receptors for IgE antibodies in cell membrane

A

Basophils

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24
Q

What cell that causes hypersensitivity reaction allergy or anaphylaxis when granules are released?

A

Mast cells

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25
Q

Invades the CT when there is inflammation and infection

A

Neutrophils

26
Q

Present only in abnormal connective tissue

A

Neutrophils

27
Q

Multilobed nucleus with granules

A

Neutrophils

28
Q

3 parts of ECM

A

Ground substance
Basement membrane
Fibers

29
Q

Types of ground substance

A

Glycosaminoglycans

Structural glycoproteins

30
Q

Types of GAGs

A 
Hyaluronic acid
Dermatan sulfate
Chondroitin sulfate
Keratan sulfate
Heparan sulfate
31
Q

GAG + core protein

A

Proteoglycans

32
Q

Involved in the interaction of cells with ECM (adhesion)

A

Structural Glycoproteins

33
Q

Examples of structural glycoproteins

A

Fibronectin
Laminin
Thrombospondin

34
Q

Part of clotting cascade and adhesion of platelets

A

Thrombospondin

35
Q

Deployed along collagen fibers

A

Fibroblast

36
Q

Contains desmosine and isodesmosine

A

Elastic fibers (elastin)

37
Q

Give rise to differentiated cells that function in repair and formation of new tissue

A

Mesenchymal cells

38
Q

Associated with allergic reaction, parasitic infection and chronic inflammation

A

Eosinophils

39
Q

Derived from monocyte

A

Macrophage

40
Q

Precursor of macrophage

41
Q

Function as APC

42
Q

Differentiate Mast cell vs Basophils

A

non-lobe nucleus (mast cell) - bilobed nucleus (basophil)

43
Q

Components of Basement membrane

A

Type IV collagen
GAGs (heparan sulfate)
Structural glycoproteins

44
Q

Makes up 30% of dry BW

45
Q

Composition of Collagen

A

Glycine 33.5%
Proline 12%
Hydroxyproline 10%

46
Q

Give the Collagen Types and corresponding locations

A

Type 1: cartilage bone
Type 2: hyaline cartilage
Type 3: located in surroundings of organs (reticular fibers)
Type 4: basement mebrane

47
Q

Example of Type III collagen

A

Reticular fibers

48
Q

composition of type iii collagen

A

made up of fibrils

49
Q

abundant in smooth muscle covering spleen and liver

A

reticular fibers

50
Q

provide supporting framework

A

reticular fibers

51
Q

35 nm in diameters/ 0.5-2 um in diameter

A

reticular fibers

52
Q

0.2 - 1 um / 10 nm in diameters

A

Elastic fibers

53
Q

what structures compose elastic fibers?

A

Central core: elastin (desmosine and isodesmosine)

Surrounding: fibrillin - glycoprotein

54
Q

allow tissue to respond to stretch and distention

A

elastic fibers

55
Q

what is elastic fiber elastic?

A

due to unusual polypeptide backbone that causes random coiling

56
Q

cause of marfan syndrome

A

abberance in elastic fibers

57
Q

similarities between elastin and collagen

A

same synthesis pathway

58
Q

ennumerate the fibers

A

collagen
reticular fibers
elastic fibers

59
Q

ennumerate connective tissue proper

A

Loose connective tissue
Dense irregular connective tissue
dense connective tissue

60
Q

examples of dense regular connective tissue

A

tendons

ligaments

61
Q

impt role in oxygen diffusion and nutrients from vessel

A

Loose connective tissue

62
Q

describe LCT

A

abundant ground substance
thin and sparse collagen
located beneath epithelium

OS 201 Exam 1 (7 decks)

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