connective tissue Flashcards

1
Q

where does CT arise from

A

Mesoderm

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2
Q

name the 3 types of CT fibres

A

collagen, reticular, elastin

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3
Q

Where is collagen made and what are its uses

A

Made from fibroblasts and uses are: cushioning, strength, found info cartilage, tendons, ligaments

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4
Q

Structure of collagen

A

3 chains of alpha helices, rich in glycine and proline

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5
Q

Reticular: what is it made from and its uses

A

Made from fibroblasts, are short fibres, in lymph nodes and bone marrow. They produce scaffolding that cells can grow through

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6
Q

Elastic fibres: where is it found

A

bundles of elastin found in ECM and smooth muscle cells in arteries

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7
Q

Structure of elastin fibres

A

Held together by cross bridges, stretch and recoil

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8
Q

What are fibroblasts and their features

A

Fibroblasts are active. Round, euchromatic nucleus, lightly stained, abundant in cytoplasm, lots of RER e.g. found in umbilicus

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9
Q

What are Fibrocytes

A

Inactive, flat, heterochromatic nucleus, scant cytoplasm, little RER e.g. found in tendons

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10
Q

what are adipocytes and their features

A

fat cells
contain lots of SER and pinocytis vesicles for endocytosis
have sleeve of collagen 3 as a coat
Are negatively charged and retain Na + and other ions. Have pockets that can store water. Can from gels

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11
Q

Difference between white and brown fat cells?

A

White: Uniocular, one large fat droplet, nucleus to the side
Brown: multiocular, many smaller droplets

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12
Q

Use of thyroid hormones?

A

Liberty fat from cells to be metabolised

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13
Q

What are GAGs

A

Glycosaminoglycans (GAGs) are long unbranched polysaccharides consisting of a repeating disaccharide unit. Examples: Hyaluronic acid, Chondroitin sulphate, Heparin sulphate, keratan sulphate

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