Connective Tissue Flashcards
1
Q
Types of Connective Tissue (6)
A
- bone
- cartilage
- blood cells
- adipose
- regular - tendons, ligaments
- irregular (fascia) - fibroblasts, collagen, elastin
2
Q
Collagen (7)
A
- loose CT
- type 1 - tendons, ligaments, fascia, capsule
- high tensile strength (3-8% creep), 50% of bone
- 1/2 life 300-600 days
- amino acids proline, glycine, lysine bond via covalent bonds - triple helix
- strong single fiber, put together = weave/extensibility
- collagen health: regular stress, nutrition, vit C; bad = steroids, nerve root impingement
3
Q
Elastin (8)
A
- protein elastin
- stretches 150% with perfect recoil, compresses to 50%
- skin, cartilage, aorta, lig flavum
- hydrophobic
- double helix
- smaller, more uniform fibers
- 80% tensile strength of collagen
- can calcify / over-stretch (elasto-calcinosis)
4
Q
Fibroblasts (5)
A
- fiber production
- combine amino acids + H-bond to make tropocollagen
- form hydrostatic covalent bonds to strengthen structures
- lie down perpendicular to stress - cross friction massage
- make ground substance (viscous gel formed by fibroblasts)
5
Q
Ground substance (4)
A
- viscous gel formed by fibroblasts
- 60-70% water
- proteoglycan:
- —-core protein bonded to GAG
- —-hydration and stabiliy
- —-resists compressive forces
- glycosaminoglycan (GAG)
- —-hyaloronic acid - holds water like cotton ball
- —-chondroitin - like gel, holds water in place
6
Q
Connectve Tissue Healing (4 phases)
A
- Reaction phase: 10 min
- Inflammatory phase: 10 min -> weeks (highest in first 2-3 days)
- Proliferation phase: 5 days (fibrogenesis)
- Maturation phase: 2-3 weeks -> 1 year+
7
Q
Scar Tissue Healing (4)
A
- 3-21 days: high production of scar tissue (manual therapy = stress to tissues to lie down properly)
- 6-8 weeks: tensile strength poor (don’t use force)
- 14 weeks: scar elongation poor (best at 3 weeks; move scar on surrounding areas)
- 6 mths-1 year: 80-100% of tensile strength
