Connective Tissue Flashcards
What type of cells are: fibroblast, mesenchymal cells, macrophage, and fat cells?
Resident cells
Connective tissue developed from which embryonic tissue?
Mesenchyme
4 fundamental tissue
Epithelial, connective, muscular, nervous
Originated locally from undifferentiated mesenchymal cells
Fibroblast
Permanent resident of connective tissue
Fixed cells
Mesenchyme is derived from which cell layer
Mesoder
Also known as histiocytes
Macrophage
Possesses the name signet ring
Fat cells
Stage of secretion and synthesis of ECM fibers and ground substance
Active stage
Mesenchymal cell is also known as
Pluripotential cells or multipotential
It is the storage of neutral fats or heat production
Fat cells
Stage where fibrocytes or mature fibroblast are in its inactive form
Quiescent stage
Transient emigrants from the blood stream
Wandering cells
A cell with features of both fibroblast and smooth muscle cells
Myofibroblast
Most common connective tissue
Fibroblast
Macrophage in the liver
Kupffer cell
Responsible for synthesis of fibers and ground substance
Fibroblast
Connective tissue cell widely sistributed in loose connective tissue
Fat cells
Macrophage in the skin
Langerhans cell
Responsible for synthesis of growth factors
Fibroblast
Macrophage in lymph nodes and spleen
Dendritic cells
Cell numerous in sites subject to penetration of bacteria and chronic inflammation
Plasma cell
Precursor of macrophage
Monocyte
Large ovoid cell, nucleus is spherical, and centrally located
Mast cell
Anti coagulant
Heparin
Fusion of several macrophage
Osteoclast
They are formed by proteins that polymerize into elongated structures
Connective tissue fibers
Several fused macrophage
Multinuclear giant cell
Cart wheel, spoke wheel or clock face appearance
Plasma cell
Present in the skin, bone, cartilage, smooth muscle, and basal lamina
Collagen fibers
Antigen processing and presenting cell
Macrophage
Precursor of plasma cell
B lymphocyte
Causes contraction of smooth muscle and increases vascular permeability
Histamine
Most numerous fibers in connective tissue
Collagen fibers
Primary function is anti bacterial
Neutrophil
Produces vasoconstriction and contraction of smooth muscle
Serotonin
Mast cell located near blood vessels
Perivascular mast cells
Fibril forming collagen resistant to tension
Type 1
Mast cell in the mucosa lining in digestive and respiratory tracts
Mucosal mast cell
Neutrophil migrate to connective tissue via
Diapedesis
Support epithelial cells
Type 4
When collagen is denatured in boiling water, it yields ____
Gelatin
Collagen resistant to pressure
Type 2
Compose of protein fibers and ground substance
Extracellular matrix
Example of mucous connective tissue
Whartons jelly of umbilical cord
Fetal or immature form of adipose tissue
Brown adipose tissue
Collagen for maintenance of expansible organs
Type 3
When elastin is treated with _____ it is selectively digested from tissue
Elastase
It is made of reticular cells and vascular smooth muscles
Reticular fibers
Elastin resist digestion by
Trypsin
Anchors basal lamina to underlying reticular lamina
Type 7
What acids does ground matrix contain?
Mucopolysacharide and glycosaminoglycan
Forms most of superficial fascia and stroma of organs
Loose connective tissue
Most numerous cells of loose connective tissue
Fibroblast and macrophage
Mucous connective tissue has an abundance of ground matrix composed chiefly of _____
Hyaluronic acid
Common adipose tissue
Yellow adipose tissue
Binds type 1 collagen fibrils, with type 5 and type 12 strengthening fiber formation
Type 14
2 unusual amino acid of elastin
Desmosine and isodesmosine
Composed of collagenous fibers arranged in bundles but are randomly oriented
Dense irregular connective tissue
Tissue found in tendons and ligaments
Elastic tissue
Supporting framework pf the bone marrow and most of lymphoid and hematopoietic organs
Reticular tissue
