Bones Flashcards
Collagen of bones
1 3 5 9 13
Non collagenous protein
Proteoglycan
Glue between collagen and hydroxy apetite crystals
Osteonectin
Mediate cell attachment and calcium phosphate formation
Sialoprotein 1 and 2
Mediate attachment of cell to bone matrix
Osteopontin
Also known as osteogenic protein
bMP 7
Assist removal of cells undergoing apoptosis
Protein S
Participates in development of vascular calcification
Matrix gla protein
Mature bones
Lamellar bones
Complex of concentric lamellae surrounding a small central canal
Harvesian system or osten
Immature bones
Wooven bones
Mineral component of bone
Calcium phosphate hydroxy apetite crystals
Space occupy by osteocytes
Lacuna
Composed of spongy bone covered by thin layer of compact bone
Epiphyses
Highly vascular and frequentyly contain red bone marrow where hematopoiesis occur
Spongy bone
Radiating through the lamellae which allow all cell to communicate with central canal
Canaliculi
Zone consist of hyaline cartilage with typical chondrocytes
Resting zone
Outer boundary pf each osteon with collagen rich fibers
Cement line
Zone where first bone tissues appear
Ossification zone
Connects central canal with each other
Volkmann canal
Zone where chondrocytes begin to divide rapidly and form columns of stack cells
Proliferative zone
Zone which contains swollen chodrocytes
Hyperthropic zone
Zone with loss of chondrocytes
Calcified cartilage zone
Process of bone formation
Osteogenesis
Dense fibrous outer layer of collagen bundles and fibroblast
Periosteum
Bone cells involved in maintaining bone mateix
Osteocytes
Thin layer of connective tissue containing flattened osteoprogenitor cells and osteoblast
Endosteum
Bone formation which forms directly from mesenchyme
Intramembranous ossification
Flat and almond shaped bone cell
Osteocytes
Bone formation within cartilage
Endochondral ossification
Rising calcium levels triggers _____ to release ____
Thyroid and calcitonin
Bone formation within membrane
Intramembranous ossification
Multinucleated cells found at sites where bone is being removed
Osteoclast
Promotes bone formation
Parathyroid hormone
Deposit new lamellae of bone matrix on the walls of these tunnels resulting in the formation of new harvesian canal
Osteoblast
Drill more or less circular tunnels within existing bone matrix
Osteoclast
______ inhibits bone resorption and stimulates calcium salt deposit in bone
Calcitonin
Falling blood calcium levels signal the ____ to release _____
Parathyroid gland and parathyroid hormone
Signals osteoclast to degrade bone matrix
Parathyroid hormone