connective tissue Flashcards
name some non- specific autoimmune diseases of connective tissue
- systemic lupus erythematosus
- rheumatoid disease
- mixed connective tissue disorders: polymyositis, dermatomyositis, sclerosis
name some tumours of the connective tissue
- lipoma
- fibroma
- osteoma
- chondroma
what type of cells make up the connective tissue
- adipocytes
- macrophages
- fibroblasts
- mast cells
what 3 things is the connective tissue made up of
cells, matrix and proteins
what does the connective tissue matrix consist of
water and solutes
what proteins (fibers) is the connective tissue made of
- collagen (for scars)
- elastic (found in aorta to withstand pressure)
- reticular (found in liver)
what is connective tissue split into
- fluid
- proper
- support
what is the fluid component of connective tissue split into
fluid and lymph
what does the support component of connective tissue split into
bone and cartilage
what does the proper component of connective tissue split into
- loose and dense
- loose splits into areolar, adipose and reticular
- dense splits into regular, irregular and elastic
why is extra-cellular matrix important in connective tissue
helps determine the physical properties of each type of connective tissue
what is the function of connective tissue
- provides metabolic and physical support to epithelial tissue
- contains blood vessels (so able to provide epithelial tissue with nutrients and oxygen)
- provides supporting network
- used as storage
- it mediates the exchange of metabolites
describe areolar tissue (type of loose connective tissue)
- areolar (small, circular area_
- vascularised (has blood vessels= provides epithelial tissue with oxygen and nutrients)
what is the function of loose connective tissue
- for physical and metabolic support
- acts as binding web
what is an example of where loose connective tissue is found
umbilical cord (wharton’s jelly)
describe adipose tissue (type of loose connective tissue)
- it is white and brown
what is the function of adipose tissue
- provides energy and insulation, acts like a cushion
describe reticular tissue (type of loose connective tissue)
- function: soft skeleton
- reticular fibers: collagen type 3
where can reticular tissue (type of loose connective tissue) be found
liver, kidneys, spleen
where can dense irregular tissue (type of dense connective tissue be found)
in the skin
where can dense regular tissue (dense connective tissue be found)
ligaments (bone to bone) and tendons (muscle to bone)
where can elastic tissue (type of dense connective tissue be found)
in the ears
where are all connective tissue derived from
from primitive mesenchyme
what can be used as musculoskeletal and cardiovascular regenerative medicine
- adult stem cells
- bioreactors
- multimodal imaging